PL2707366T3 - Ko-kryształy (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorofenylo)tiofen-2-ylo)metylo)-4-metylofenylo)-6-(hydroksymetylo)tetrahydro-2H-pirano-3,4,5-triolu z L-proliną i z kwasem cytrynowym - Google Patents

Ko-kryształy (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorofenylo)tiofen-2-ylo)metylo)-4-metylofenylo)-6-(hydroksymetylo)tetrahydro-2H-pirano-3,4,5-triolu z L-proliną i z kwasem cytrynowym

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Publication number
PL2707366T3
PL2707366T3 PL12723013T PL12723013T PL2707366T3 PL 2707366 T3 PL2707366 T3 PL 2707366T3 PL 12723013 T PL12723013 T PL 12723013T PL 12723013 T PL12723013 T PL 12723013T PL 2707366 T3 PL2707366 T3 PL 2707366T3
Authority
PL
Poland
Prior art keywords
thiophen
triol
pyran
fluorophenyl
proline
Prior art date
Application number
PL12723013T
Other languages
English (en)
Inventor
Minh Nguyen
Edwin A Collier
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46147741&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2707366(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PL2707366T3 publication Critical patent/PL2707366T3/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/22—Tricarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL12723013T 2011-05-09 2012-05-09 Ko-kryształy (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorofenylo)tiofen-2-ylo)metylo)-4-metylofenylo)-6-(hydroksymetylo)tetrahydro-2H-pirano-3,4,5-triolu z L-proliną i z kwasem cytrynowym PL2707366T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161483887P 2011-05-09 2011-05-09
PCT/US2012/037062 WO2012154812A1 (en) 2011-05-09 2012-05-09 L-proline and citric acid co-crystals of (2s, 3r, 4r, 5s, 6r )- 2- (3- ((5- (4-fluorophenyl)thiophen-2-yl) methyl) -4-methylphenyl)-6- (hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol
EP12723013.4A EP2707366B1 (en) 2011-05-09 2012-05-09 L-proline and citric acid co-crystals of (2s, 3r, 4r, 5s, 6r )- 2- (3- ((5- (4-fluorophenyl)thiophen-2-yl) methyl) -4-methylphenyl)-6- (hydroxymethyl)tetrahydro-2h-pyran-3,4,5-triol

Publications (1)

Publication Number Publication Date
PL2707366T3 true PL2707366T3 (pl) 2015-11-30

Family

ID=46147741

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12723013T PL2707366T3 (pl) 2011-05-09 2012-05-09 Ko-kryształy (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorofenylo)tiofen-2-ylo)metylo)-4-metylofenylo)-6-(hydroksymetylo)tetrahydro-2H-pirano-3,4,5-triolu z L-proliną i z kwasem cytrynowym

Country Status (32)

Country Link
US (1) US9035044B2 (pl)
EP (1) EP2707366B1 (pl)
JP (1) JP6106661B2 (pl)
KR (1) KR101795514B1 (pl)
CN (2) CN103502245B (pl)
AR (1) AR086320A1 (pl)
AU (1) AU2012253613B2 (pl)
BR (1) BR112013028744B1 (pl)
CA (2) CA3050525C (pl)
CL (1) CL2013003209A1 (pl)
CY (1) CY1116550T1 (pl)
DK (1) DK2707366T3 (pl)
EA (1) EA023496B1 (pl)
ES (1) ES2546904T3 (pl)
HR (1) HRP20151011T1 (pl)
HU (1) HUE027642T2 (pl)
IL (1) IL229232A (pl)
ME (1) ME02175B (pl)
MX (1) MX347178B (pl)
MY (1) MY166774A (pl)
PH (1) PH12013502274A1 (pl)
PL (1) PL2707366T3 (pl)
PT (1) PT2707366E (pl)
RS (1) RS54205B1 (pl)
SG (1) SG194767A1 (pl)
SI (1) SI2707366T1 (pl)
SM (1) SMT201500194B (pl)
TW (1) TWI542596B (pl)
UA (1) UA111199C2 (pl)
UY (1) UY34061A (pl)
WO (1) WO2012154812A1 (pl)
ZA (1) ZA201309212B (pl)

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CN105503802A (zh) * 2016-01-15 2016-04-20 中山大学 一种达格列净-柠檬酸共晶的制备方法
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CN109563024B (zh) * 2016-06-13 2023-06-06 心悦生医股份有限公司 苯甲酸锂的共晶及其用途
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KR20210065974A (ko) * 2018-09-26 2021-06-04 렉시컨 파마슈티컬스 인코퍼레이티드 N-(1-((2-(디메틸아미노)에틸)아미노)-2-메틸-1-옥소프로판-2-일)-4-(4-(2-메틸-5-((2s,3r,4r,5s,6r)-3,4,5-트리히드록시-6-(메틸티오)테트라히드로-2h-피란-2-일)벤질)페닐)부탄아미드의 결정질 형태 및 그의 합성 방법
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