PL2322183T3 - Wykorzystanie proleku do podawania doocznego, śródszklistkowego - Google Patents

Wykorzystanie proleku do podawania doocznego, śródszklistkowego

Info

Publication number
PL2322183T3
PL2322183T3 PL10177375T PL10177375T PL2322183T3 PL 2322183 T3 PL2322183 T3 PL 2322183T3 PL 10177375 T PL10177375 T PL 10177375T PL 10177375 T PL10177375 T PL 10177375T PL 2322183 T3 PL2322183 T3 PL 2322183T3
Authority
PL
Poland
Prior art keywords
prodrugs
ocular
intravitreous administration
intravitreous
administration
Prior art date
Application number
PL10177375T
Other languages
English (en)
Inventor
Grégory Lambert
Laura Rabinovich-Guilatt
Original Assignee
Santen Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Sas filed Critical Santen Sas
Publication of PL2322183T3 publication Critical patent/PL2322183T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL10177375T 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego PL2322183T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06290902A EP1864668B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration
EP10177375.2A EP2322183B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration
EP06290901.5A EP1864667B1 (en) 2006-06-01 2006-06-01 Use of prodrugs for ocular intravitreous administration
US11/444,349 US20070280902A1 (en) 2006-06-01 2006-06-01 Method for treating eye disease or conditions affecting the posterior segment of the eye
US11/444,337 US20070281914A1 (en) 2006-06-01 2006-06-01 Use of a steroid prodrug for the treatment of disease of the posterior segment of the eye

Publications (1)

Publication Number Publication Date
PL2322183T3 true PL2322183T3 (pl) 2015-01-30

Family

ID=39712456

Family Applications (4)

Application Number Title Priority Date Filing Date
PL10177375T PL2322183T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL10177382T PL2319517T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL06290902T PL1864668T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do okulistycznego podawania śródszklistkowego
PL06290901T PL1864667T3 (pl) 2006-06-01 2006-06-01 Zastosowanie proleków do podania do ciała szklistego oka

Family Applications After (3)

Application Number Title Priority Date Filing Date
PL10177382T PL2319517T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do podawania doocznego, śródszklistkowego
PL06290902T PL1864668T3 (pl) 2006-06-01 2006-06-01 Wykorzystanie proleku do okulistycznego podawania śródszklistkowego
PL06290901T PL1864667T3 (pl) 2006-06-01 2006-06-01 Zastosowanie proleków do podania do ciała szklistego oka

Country Status (14)

Country Link
US (4) US20070280902A1 (pl)
EP (4) EP2322183B1 (pl)
JP (2) JP5455624B2 (pl)
KR (1) KR101408317B1 (pl)
CN (1) CN101553235B (pl)
AU (1) AU2007267079B2 (pl)
CA (1) CA2653902C (pl)
DK (2) DK2319517T3 (pl)
ES (1) ES2399976T3 (pl)
IL (1) IL195626A (pl)
PL (4) PL2322183T3 (pl)
PT (2) PT1864667E (pl)
SI (1) SI1864668T1 (pl)
WO (2) WO2007138113A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322183B1 (en) 2006-06-01 2014-10-22 Santen SAS Use of prodrugs for ocular intravitreous administration
EP2214646B1 (en) 2007-10-05 2021-06-23 Wayne State University Dendrimers for sustained release of compounds
US8623852B2 (en) 2007-12-04 2014-01-07 Santen Sas Topical methods and compositions for the treatment of eye diseases and conditions
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP5591226B2 (ja) 2008-05-12 2014-09-17 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 眼内薬物送達装置および関連する方法
UA111867C2 (uk) 2011-11-11 2016-06-24 Аллерган, Інк. ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ І СПОСІБ ЗАСТОСУВАННЯ ПОХІДНИХ 4-ПРЕГНЕН-11β-17-21-ТРІОЛ-3,20-ДІОНУ
CN107260679B (zh) * 2012-02-10 2020-07-31 台湾微脂体股份有限公司 用以减少眼用类固醇的并发症的药物组合物
CN110944668A (zh) 2017-06-16 2020-03-31 学校法人同志社 用于治疗或预防眼部症状、障碍或疾病的包含mTOR抑制剂的药物及其应用
CA3082121C (en) 2017-11-10 2023-01-24 The Johns Hopkins University Dendrimer delivery system and methods of use thereof
CN111068071A (zh) * 2018-10-22 2020-04-28 武汉纽福斯生物科技有限公司 基因治疗Leber遗传学视神经病变
MA54325A (fr) 2019-06-05 2022-05-11 Regeneron Pharma Dispositifs et procédés pour l'administration précise de doses
EP3871662B1 (en) * 2020-02-25 2023-06-07 Labomed Pharmaceutical Company S.A. Oral solutions comprising fludrocortisone acetate
CN116367824A (zh) 2020-09-16 2023-06-30 桑腾股份有限公司 用于玻璃体内施用的水包油乳剂
USD1120314S1 (en) 2022-11-30 2026-03-24 Regeneron Pharmaceuticals, Inc. Dose delivery device
WO2024167694A2 (en) * 2023-02-06 2024-08-15 Celularity Inc. Placental extracellular matrices for ocular delivery of ophthalmic therapeutic agents

Family Cites Families (29)

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JPS609726B2 (ja) 1980-05-15 1985-03-12 株式会社 ミドリ十字 ステロイド製剤
JPS5716818A (en) 1981-04-25 1982-01-28 Green Cross Corp:The Steroid fatty emulsion
AU531588B2 (en) 1981-08-17 1983-09-01 Yoshitomi Pharmaceutical Industries, Ltd. Emulsifying water-insoluble steroid
EP0244178A3 (en) 1986-04-28 1989-02-08 Iolab, Inc Intraocular dosage compositions and method of use
WO1990001933A1 (en) 1988-08-26 1990-03-08 Alcon Laboratories, Inc. Combination of quinolone antibiotics and steroids for topical ophthalmic use
JPH05132498A (ja) 1991-11-08 1993-05-28 Asahi Glass Co Ltd ステロイド誘導体およびその製剤
IL101241A (en) 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
CA2125060C (en) 1993-07-02 1999-03-30 Henry P. Dabrowski Ophthalmic solution for artificial tears
WO1995004030A1 (en) * 1993-08-02 1995-02-09 Commonwealth Scientific And Industrial Research Organisation Therapeutic compound - fatty acid conjugates
ES2094688B1 (es) 1994-08-08 1997-08-01 Cusi Lab Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
DE69807281T2 (de) 1997-05-14 2003-04-17 Mitsubishi Chemical Corp., Tokio/Tokyo Difluprednat enthaltende Zusammensetzungen
JP3410364B2 (ja) 1997-05-14 2003-05-26 千寿製薬株式会社 ジフルプレドナート含有組成物
IL121647A (en) * 1997-08-28 2001-07-24 Pharmateam Dev Ltd Pharmaceutical compositions for the treatment of ocular inflammation comprising dexamethasone palmitate
AU9281698A (en) 1997-10-01 1999-04-23 Wakamoto Pharmaceutical Co., Ltd. O/w emulsion compositions
JP2000212067A (ja) * 1999-01-19 2000-08-02 Towa Yakuhin Kk 薬物含有エマルジョン製剤
IL161588A0 (en) 2001-11-01 2004-09-27 Yissum Res Dev Co Method and composition for dry eye treatment
JP2006513217A (ja) * 2002-12-20 2006-04-20 コントロール・デリバリー・システムズ・インコーポレイテッド 眼内用途のためのステロイド組成物
US20050009910A1 (en) * 2003-07-10 2005-01-13 Allergan, Inc. Delivery of an active drug to the posterior part of the eye via subconjunctival or periocular delivery of a prodrug
ATE416761T1 (de) * 2003-09-22 2008-12-15 Onepharm Res & Dev Gmbh Prävention und behandlung von durch entzündung ausgelöstem und/oder immunvermitteltem knochenschwund
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ATE439123T1 (de) * 2004-07-02 2009-08-15 Novagali Pharma Sa Verwendung von emulsionen zur intra- und periocularen injection
CA2573668A1 (en) 2004-07-12 2006-02-16 Allergan, Inc. Ophthalmic compositions and methods for treating ophthalmic conditions
EP3173072A1 (en) * 2004-10-01 2017-05-31 Ramscor, Inc. Conveniently implantable sustained release drug compositions
US20060094700A1 (en) * 2004-11-02 2006-05-04 Allergan, Inc. Heat sterilization of a steroid in the presence of phosphate
KR101319772B1 (ko) 2004-11-09 2013-10-23 노바갈리 파르마 에스 에이 면역 억제제를 포함하는 안과용 유제
CN1905012A (zh) 2005-07-31 2007-01-31 新科实业有限公司 具有微驱动器的磁头折片组合及其磁盘驱动装置
US8109884B2 (en) 2005-09-23 2012-02-07 Kitchener Clark Wilson Dynamic metabolism monitoring system
EP2322183B1 (en) 2006-06-01 2014-10-22 Santen SAS Use of prodrugs for ocular intravitreous administration

Also Published As

Publication number Publication date
CA2653902C (en) 2015-03-17
DK2319517T3 (da) 2013-12-09
US20070280995A1 (en) 2007-12-06
PL1864668T3 (pl) 2013-04-30
KR20090031373A (ko) 2009-03-25
HK1110221A1 (en) 2008-07-11
EP2322183A1 (en) 2011-05-18
EP1864668B1 (en) 2012-11-21
EP2319517A1 (en) 2011-05-11
ES2399976T3 (es) 2013-04-04
EP1864667B1 (en) 2013-09-04
CA2653902A1 (en) 2007-12-06
KR101408317B1 (ko) 2014-06-17
JP2009538879A (ja) 2009-11-12
US20070281913A1 (en) 2007-12-06
EP2322183B1 (en) 2014-10-22
PT1864668E (pt) 2013-02-26
CN101553235B (zh) 2012-12-05
PL1864667T3 (pl) 2014-01-31
AU2007267079A1 (en) 2007-12-06
WO2007138114A1 (en) 2007-12-06
US9192567B2 (en) 2015-11-24
AU2007267079B2 (en) 2013-01-31
EP1864667A1 (en) 2007-12-12
JP5455624B2 (ja) 2014-03-26
US20070280902A1 (en) 2007-12-06
CN101553235A (zh) 2009-10-07
HK1110219A1 (en) 2008-07-11
SI1864668T1 (sl) 2013-04-30
IL195626A (en) 2017-05-29
JP2009538880A (ja) 2009-11-12
DK1864668T3 (da) 2013-03-04
US8227452B2 (en) 2012-07-24
JP5284953B2 (ja) 2013-09-11
EP1864668A1 (en) 2007-12-12
EP2319517B1 (en) 2013-09-11
PL2319517T3 (pl) 2014-01-31
IL195626A0 (en) 2009-09-01
WO2007138113A1 (en) 2007-12-06
US20070281914A1 (en) 2007-12-06
PT1864667E (pt) 2013-11-18

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