PL2152667T3 - Sposoby wytwarzania pochodnych N-izobutylo-N-(2-hydroksy-3-amino-4-fenylo-butylo)-p-nitrobenzenosulfonyloamidu - Google Patents
Sposoby wytwarzania pochodnych N-izobutylo-N-(2-hydroksy-3-amino-4-fenylo-butylo)-p-nitrobenzenosulfonyloamiduInfo
- Publication number
- PL2152667T3 PL2152667T3 PL08749718T PL08749718T PL2152667T3 PL 2152667 T3 PL2152667 T3 PL 2152667T3 PL 08749718 T PL08749718 T PL 08749718T PL 08749718 T PL08749718 T PL 08749718T PL 2152667 T3 PL2152667 T3 PL 2152667T3
- Authority
- PL
- Poland
- Prior art keywords
- hydroxy
- phenylbutyl
- isobutyl
- amino
- preparation
- Prior art date
Links
- RXZQKCYDYRLICS-UHFFFAOYSA-N [3-hydroxy-4-(2-methylpropylamino)-1-phenylbutan-2-yl]carbamic acid Chemical class CC(C)CNCC(O)C(NC(O)=O)CC1=CC=CC=C1 RXZQKCYDYRLICS-UHFFFAOYSA-N 0.000 abstract 1
- -1 p-nitrophenylsulfonyl halide Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07107177 | 2007-04-27 | ||
| PCT/EP2008/055042 WO2008132154A1 (en) | 2007-04-27 | 2008-04-25 | Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives |
| EP08749718A EP2152667B1 (en) | 2007-04-27 | 2008-04-25 | Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2152667T3 true PL2152667T3 (pl) | 2011-06-30 |
Family
ID=38924830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08749718T PL2152667T3 (pl) | 2007-04-27 | 2008-04-25 | Sposoby wytwarzania pochodnych N-izobutylo-N-(2-hydroksy-3-amino-4-fenylo-butylo)-p-nitrobenzenosulfonyloamidu |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US8076513B2 (pl) |
| EP (1) | EP2152667B1 (pl) |
| JP (1) | JP2010525029A (pl) |
| CN (1) | CN101668734A (pl) |
| AT (1) | ATE498606T1 (pl) |
| AU (1) | AU2008244306A1 (pl) |
| BR (1) | BRPI0810609A2 (pl) |
| CA (1) | CA2682616A1 (pl) |
| CY (1) | CY1111457T1 (pl) |
| DE (1) | DE602008005012D1 (pl) |
| DK (1) | DK2152667T3 (pl) |
| ES (1) | ES2360654T3 (pl) |
| HR (1) | HRP20110290T1 (pl) |
| IL (1) | IL200811A0 (pl) |
| MX (1) | MX2009011574A (pl) |
| PL (1) | PL2152667T3 (pl) |
| PT (1) | PT2152667E (pl) |
| RU (1) | RU2009143867A (pl) |
| SI (1) | SI2152667T1 (pl) |
| WO (1) | WO2008132154A1 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8921415B2 (en) | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
| CN102725295A (zh) | 2010-01-28 | 2012-10-10 | Mapi医药公司 | 制备达芦那韦和达芦那韦中间体的方法 |
| WO2011158259A1 (en) * | 2010-06-18 | 2011-12-22 | Matrix Laboratories Ltd | Novel process for the preparation of (3s)-tetrahydrofuran-3-yl (is, 2r)-3-[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-(phosphonooxy) propylcarbamate and its pharmaceutically acceptable salts thereof |
| WO2012070057A1 (en) | 2010-11-23 | 2012-05-31 | Matrix Laboratories Ltd | Process for the preparation of (3r, 3as, 6ar)-hexahydrofuro [2, 3- b] furan-3-ol |
| CN105315178B (zh) * | 2014-07-09 | 2018-07-06 | 浙江九洲药业股份有限公司 | 达芦那韦相关物质及其制备方法 |
| CN117142989A (zh) * | 2020-12-30 | 2023-12-01 | 上海飞腾医药科技有限公司 | 一种抗hiv类药物中间体晶体a的生长方法和所得晶体 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3000377A1 (de) * | 1980-01-07 | 1981-07-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue sulfonamide, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| JPH07110846B2 (ja) * | 1987-12-23 | 1995-11-29 | アグロカネショウ株式会社 | 置換ベンジルスルホアミド誘導体、その製法及び選択性除草剤 |
| DK0810209T3 (da) * | 1992-08-25 | 2002-08-12 | Monsanto Co | Alpha - and beta-aminosyre-hydroxyethylaminosulfonamider til anvendelse som inhibitorer af retrovirale proteaser |
| IS2334B (is) | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
| AU7669794A (en) | 1993-08-24 | 1995-03-21 | G.D. Searle & Co. | Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors |
| US5929284A (en) | 1995-02-03 | 1999-07-27 | Kaneka Corporation | Processes for producing α-halo ketones, α-halohydrins and epoxides |
| JP2000515488A (ja) | 1995-11-15 | 2000-11-21 | ジー．ディー．サール アンド カンパニー | 置換スルホニルアルカノイルアミノヒドロキシエチルアミノスルホンアミド レトロウイルスプロテアーゼ阻害剤 |
| AU767728B2 (en) | 1998-06-19 | 2003-11-20 | Vertex Pharmaceuticals Incorporated | Sulfonamide inhibitors of aspartyl protease |
| ES2604662T3 (es) | 1998-06-23 | 2017-03-08 | The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Ensayo de acondicionamiento físico y métodos para reducir la resistencia del VIH a la terapia |
| AU4828199A (en) | 1998-06-23 | 2000-01-10 | Board Of Trustees Of The University Of Illinois, The | Multi-drug resistant retroviral protease inhibitors and associated methods |
| ATE269314T1 (de) | 1998-08-25 | 2004-07-15 | Kaneka Corp | Verfahren zur herstellung von (2r, 3s)-amino-1,2- oxiran |
| EP1067125B1 (en) | 1999-01-29 | 2006-07-26 | Kaneka Corporation | PROCESSES FOR THE PREPARATION OF threo-1,2-EPOXY-3-AMINO-4-PHENYLBUTANE DERIVATIVES |
| ES2254156T3 (es) | 1999-02-12 | 2006-06-16 | Vertex Pharmaceuticals Incorporated | Inhibidores de aspartil-proteasa. |
| AR031520A1 (es) | 1999-06-11 | 2003-09-24 | Vertex Pharma | Un compuesto inhibidor de aspartilo proteasa, una composicion que lo comprende y un metodo para tratar un paciente con dicha composicion |
| KR100708221B1 (ko) | 1999-08-31 | 2007-04-17 | 아지노모토 가부시키가이샤 | 에폭사이드 결정의 제조방법 |
| WO2001046120A1 (en) | 1999-12-23 | 2001-06-28 | Aerojet Fine Chemicals Llc | Improved preparation of 2s,3s-n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide hydrochloride and other derivatives of 2-hydroxy-1,3-diamines |
| US6764545B2 (en) | 2000-12-12 | 2004-07-20 | Ajinomoto Co., Inc. | Production method of epoxide crystal |
| JP2002332270A (ja) * | 2001-03-07 | 2002-11-22 | Ajinomoto Co Inc | スルホンアミド誘導体の製造方法 |
| JP4521185B2 (ja) | 2001-09-10 | 2010-08-11 | テイボテク・フアーマシユーチカルズ・リミテツド | ヘキサヒドロ−フロ［２，３−ｂ］フラン−３−オールの製造法 |
| AU2003287038A1 (en) | 2002-10-09 | 2004-05-04 | The Board Of Trustees Of The University Of Illinois | METHOD OF PREPARING (3R, 3aS, 6aR) -3- HYDROXYHEXAHYDROFURO (2, 3-b) FURAN AND RELATED COMPOUNDS |
| AU2003275675A1 (en) | 2002-12-27 | 2004-07-29 | Sumitomo Chemical Company, Limited | Process for producing hexahydrofurofuranol derivative, intermediate thereof and process for producing the same |
| UA79404C2 (en) * | 2003-10-02 | 2007-06-11 | Basf Ag | 2-cyanobenzenesulfonamide for controlling pests |
| HRP20090488T1 (hr) * | 2003-12-23 | 2009-10-31 | Tibotec Pharmaceuticals Ltd. | Postupak za pripravu (3r,3as,6ar)-heksahidrofuro[2,3-b]furan-3-il(1s,23)-3-[[(4-aminofenil)sulfonil](izobutil)amino]-1-benzil-2-hidroksipropilkarbamata |
| TWI383975B (zh) | 2004-03-31 | 2013-02-01 | 悌柏泰克醫藥有限公司 | 製備（３Ｒ，３ａＳ，６ａＲ）六氫-呋喃并〔２，３-ｂ〕呋喃-３-醇之方法 |
-
2008
- 2008-04-25 PL PL08749718T patent/PL2152667T3/pl unknown
- 2008-04-25 BR BRPI0810609-6A2A patent/BRPI0810609A2/pt not_active IP Right Cessation
- 2008-04-25 CN CN200880013559A patent/CN101668734A/zh active Pending
- 2008-04-25 AT AT08749718T patent/ATE498606T1/de active
- 2008-04-25 MX MX2009011574A patent/MX2009011574A/es active IP Right Grant
- 2008-04-25 HR HR20110290T patent/HRP20110290T1/hr unknown
- 2008-04-25 DK DK08749718.6T patent/DK2152667T3/da active
- 2008-04-25 CA CA002682616A patent/CA2682616A1/en not_active Abandoned
- 2008-04-25 ES ES08749718T patent/ES2360654T3/es active Active
- 2008-04-25 EP EP08749718A patent/EP2152667B1/en not_active Not-in-force
- 2008-04-25 PT PT08749718T patent/PT2152667E/pt unknown
- 2008-04-25 JP JP2010504703A patent/JP2010525029A/ja active Pending
- 2008-04-25 DE DE602008005012T patent/DE602008005012D1/de active Active
- 2008-04-25 US US12/597,088 patent/US8076513B2/en not_active Expired - Fee Related
- 2008-04-25 AU AU2008244306A patent/AU2008244306A1/en not_active Abandoned
- 2008-04-25 RU RU2009143867/04A patent/RU2009143867A/ru not_active Application Discontinuation
- 2008-04-25 SI SI200830232T patent/SI2152667T1/sl unknown
- 2008-04-25 WO PCT/EP2008/055042 patent/WO2008132154A1/en not_active Ceased
-
2009
- 2009-09-08 IL IL200811A patent/IL200811A0/en unknown
-
2011
- 2011-05-16 CY CY20111100463T patent/CY1111457T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1111457T1 (el) | 2015-08-05 |
| BRPI0810609A2 (pt) | 2014-10-21 |
| CA2682616A1 (en) | 2008-11-06 |
| EP2152667A1 (en) | 2010-02-17 |
| US8076513B2 (en) | 2011-12-13 |
| JP2010525029A (ja) | 2010-07-22 |
| IL200811A0 (en) | 2010-05-17 |
| RU2009143867A (ru) | 2011-06-10 |
| EP2152667B1 (en) | 2011-02-16 |
| DE602008005012D1 (de) | 2011-03-31 |
| CN101668734A (zh) | 2010-03-10 |
| DK2152667T3 (da) | 2011-05-16 |
| PT2152667E (pt) | 2011-04-06 |
| ATE498606T1 (de) | 2011-03-15 |
| MX2009011574A (es) | 2009-11-09 |
| US20100121094A1 (en) | 2010-05-13 |
| HRP20110290T1 (hr) | 2011-05-31 |
| WO2008132154A1 (en) | 2008-11-06 |
| AU2008244306A1 (en) | 2008-11-06 |
| SI2152667T1 (sl) | 2011-06-30 |
| ES2360654T3 (es) | 2011-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2011008946A (es) | Un complejo de haluro de hidrogeno de agomelatina y la preparacion del mismo. | |
| IL200811A0 (en) | Methods for the preparation of n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives | |
| MX2009001840A (es) | Procedimiento para la preparacion de derivados de acido 3-dihalometilpirazol-4-carboxilico. | |
| MY158251A (en) | Method for the preparation of nalmefene hydrochloride | |
| WO2012031045A3 (en) | Phosphonate ester derivatives and methods of synthesis thereof | |
| IL192847A (en) | The history of benzamide and the trower, a process for making them and their pharmaceutical preparations | |
| CY1111690T1 (el) | Μεθοδος για την παρασκευη δροσπιρενονης | |
| EP4417605A3 (en) | Method for synthesis of eliglustat and intermediate compounds thereof | |
| PH12012500287A1 (en) | K5 heparosan fermentation and purification | |
| NZ603653A (en) | Processes for the preparation of dipyridamole | |
| WO2008099286A3 (en) | Improved process for preparing ethyl (s)-2-ethoxy-4-[n-[1-(2- piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of repaglinide | |
| MY155962A (en) | Photochemical process for producing artemisinin | |
| PH12013500609A1 (en) | Novel method of preparing benzoimidazole derivatives | |
| MY146357A (en) | Process for the preparation of pleuromutilins | |
| WO2014133291A9 (ko) | (2rs)-아미노-(3s)-히드록시-부티르산 또는 이의 유도체의 제조방법 | |
| NZ589496A (en) | Processes and compounds for the preparation of normorphinans | |
| WO2011048612A3 (en) | Process for preparation of propargylated aminoindans or pharmaceutically acceptable salts thereof | |
| WO2010110771A3 (en) | Substituted thiol-containing alkyl fatty acids and process for synthesizing derivatives thereof | |
| EP1572657A4 (en) | PROCESS FOR THE PREPARATION OF CHINOLONCARBOXYLATE DERIVATIVES | |
| DK1828178T3 (da) | Fremgangsmåde til fremstilling af meloxicam og meloxicamkaliumsalt med høj renhed | |
| WO2008152518A3 (en) | Process for the preparation of risedronic acid or risedronate sodium | |
| WO2007015257A3 (en) | A process for the preparation of gemcitabine using novel intermediates | |
| WO2010004580A3 (en) | Process for preparing indole derivatives | |
| WO2009066317A3 (en) | Process for the preparation of pantoprazole sodium | |
| MX2009001508A (es) | Un proceso novedoso para preparar ester de acido 3-amino-5-fluoro-4-dialcoxipentanoico. |