WO2010004580A3 - Process for preparing indole derivatives - Google Patents
Process for preparing indole derivatives Download PDFInfo
- Publication number
- WO2010004580A3 WO2010004580A3 PCT/IN2009/000385 IN2009000385W WO2010004580A3 WO 2010004580 A3 WO2010004580 A3 WO 2010004580A3 IN 2009000385 W IN2009000385 W IN 2009000385W WO 2010004580 A3 WO2010004580 A3 WO 2010004580A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- indole derivatives
- preparing indole
- formula
- indole
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Abstract
The present invention provides a process for the preparation of indole derivatives, specifically N- methyl-1H-indole-5-ethanesulfonamide of formula (I), involving novel intermediate, which is used as key intermediate for the synthesis of naratriptan of formula (II), and its pharmaceutically acceptable salts thereof high yield and purity.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1671/DEL/2008 | 2008-07-11 | ||
IN1671DE2008 | 2008-07-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010004580A2 WO2010004580A2 (en) | 2010-01-14 |
WO2010004580A3 true WO2010004580A3 (en) | 2011-03-31 |
Family
ID=41507516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2009/000385 WO2010004580A2 (en) | 2008-07-11 | 2009-07-08 | Process for preparing indole derivatives |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2010004580A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102964287B (en) * | 2012-11-13 | 2014-04-09 | 苏州永健生物医药有限公司 | Synthesis method of 3-(4-chlorobutyl)-5-cyanoindole |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0303507A2 (en) * | 1987-08-13 | 1989-02-15 | Glaxo Group Limited | Indole derivatives |
WO2008056378A2 (en) * | 2006-11-09 | 2008-05-15 | Natco Pharma Limited | Novel process for the preparation of naratriptan hydrochloride |
-
2009
- 2009-07-08 WO PCT/IN2009/000385 patent/WO2010004580A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0303507A2 (en) * | 1987-08-13 | 1989-02-15 | Glaxo Group Limited | Indole derivatives |
WO2008056378A2 (en) * | 2006-11-09 | 2008-05-15 | Natco Pharma Limited | Novel process for the preparation of naratriptan hydrochloride |
Also Published As
Publication number | Publication date |
---|---|
WO2010004580A2 (en) | 2010-01-14 |
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