WO2009116072A3 - Process for preparation of pyridinylmethylsulphinyl benzimidazole compounds and pyridine intermediates - Google Patents

Process for preparation of pyridinylmethylsulphinyl benzimidazole compounds and pyridine intermediates Download PDF

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Publication number
WO2009116072A3
WO2009116072A3 PCT/IN2009/000080 IN2009000080W WO2009116072A3 WO 2009116072 A3 WO2009116072 A3 WO 2009116072A3 IN 2009000080 W IN2009000080 W IN 2009000080W WO 2009116072 A3 WO2009116072 A3 WO 2009116072A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
pyridinylmethylsulphinyl
benzimidazole compounds
pyridine intermediates
intermediates
Prior art date
Application number
PCT/IN2009/000080
Other languages
French (fr)
Other versions
WO2009116072A2 (en
Inventor
Ashok Kumar
Kishor Ramdas More
Palani Muniyan Gounder
Pushkar Naresh Patil
Tatyaba Dashrath Bhor
Santosh Shankar Chikane
Sangharakshit Nusa Darunde
Original Assignee
Ipca Laboratories Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipca Laboratories Limited filed Critical Ipca Laboratories Limited
Publication of WO2009116072A2 publication Critical patent/WO2009116072A2/en
Publication of WO2009116072A3 publication Critical patent/WO2009116072A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

Process for preparing 4-chloro-substituted pyridine intermediates of Formula (I), useful for preparation of pyridinylmethylsulphinyl benzimidazole compounds, especially Rabeprazole is disclosed herein. The invention, further describes process for preparation of stable Rabeprazole sodium of high purity in a reproducible & consistent manner.
PCT/IN2009/000080 2008-02-08 2009-02-05 Process for preparation of pyridinylmethylsulphinyl benzimidazole compounds and pyridine intermediates WO2009116072A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN278/MUM/2008 2008-02-08
IN278MU2008 2008-02-08

Publications (2)

Publication Number Publication Date
WO2009116072A2 WO2009116072A2 (en) 2009-09-24
WO2009116072A3 true WO2009116072A3 (en) 2012-10-04

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ID=41091333

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000080 WO2009116072A2 (en) 2008-02-08 2009-02-05 Process for preparation of pyridinylmethylsulphinyl benzimidazole compounds and pyridine intermediates

Country Status (1)

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WO (1) WO2009116072A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102838537B (en) * 2012-09-18 2014-04-09 寿光富康制药有限公司 Preparation method of lansoprazole intermediate
CN105294652A (en) * 2012-10-25 2016-02-03 天津汉瑞药业有限公司 Rabeprazole sodium compound
WO2014091450A1 (en) 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Process for the preparation of rabeprazole
CN105085481B (en) * 2014-05-19 2017-09-29 南京长澳医药科技有限公司 A kind of recrystallization method of RABEPRAZOLE SODIUM
CN106083705A (en) * 2016-06-14 2016-11-09 上药康丽（常州）药业有限公司 The preparation method of 2 methylol 4 (methoxy propoxy) 3 methyl pyridinium chloride

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU447405A1 (en) * 1973-01-08 1974-10-25 Донецкое Отделение Физико-Органической Химии Института Физической Химии Им.Л.В.Писаржевского Ан Украинской Сср Method for preparing 3-alkylamino or 3-dialkylamino-4-chloropyridine-α-oxides
EP0175464A1 (en) * 1984-08-16 1986-03-26 Takeda Chemical Industries, Ltd. Benzimidazole derivatives and their production

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU447405A1 (en) * 1973-01-08 1974-10-25 Донецкое Отделение Физико-Органической Химии Института Физической Химии Им.Л.В.Писаржевского Ан Украинской Сср Method for preparing 3-alkylamino or 3-dialkylamino-4-chloropyridine-α-oxides
EP0175464A1 (en) * 1984-08-16 1986-03-26 Takeda Chemical Industries, Ltd. Benzimidazole derivatives and their production

Also Published As

Publication number Publication date
WO2009116072A2 (en) 2009-09-24

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