WO2009075516A3 - Process for preparing pantoprazole sodium sesquihydrate - Google Patents

Process for preparing pantoprazole sodium sesquihydrate Download PDF

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Publication number
WO2009075516A3
WO2009075516A3 PCT/KR2008/007294 KR2008007294W WO2009075516A3 WO 2009075516 A3 WO2009075516 A3 WO 2009075516A3 KR 2008007294 W KR2008007294 W KR 2008007294W WO 2009075516 A3 WO2009075516 A3 WO 2009075516A3
Authority
WO
WIPO (PCT)
Prior art keywords
pantoprazole sodium
sodium sesquihydrate
preparing pantoprazole
preparing
sesquihydrate
Prior art date
Application number
PCT/KR2008/007294
Other languages
French (fr)
Other versions
WO2009075516A2 (en
Inventor
Kyu-Jung Wang
Young-Deuck Kim
Original Assignee
Dongwoo Syntech Co., Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dongwoo Syntech Co., Ltd filed Critical Dongwoo Syntech Co., Ltd
Publication of WO2009075516A2 publication Critical patent/WO2009075516A2/en
Publication of WO2009075516A3 publication Critical patent/WO2009075516A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole

Abstract

Disclosed herein is a process for preparation of pantoprazole sodium sesquihydrate represented by Formula 1 from pantoprazole as a starting material.
PCT/KR2008/007294 2007-12-11 2008-12-10 Process for preparing pantoprazole sodium sesquihydrate WO2009075516A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020070127993A KR100939216B1 (en) 2007-12-11 2007-12-11 Process for preparing Pantoprazole Sodium Sesquihydrate
KR10-2007-0127993 2007-12-11

Publications (2)

Publication Number Publication Date
WO2009075516A2 WO2009075516A2 (en) 2009-06-18
WO2009075516A3 true WO2009075516A3 (en) 2009-09-03

Family

ID=40755981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/007294 WO2009075516A2 (en) 2007-12-11 2008-12-10 Process for preparing pantoprazole sodium sesquihydrate

Country Status (2)

Country Link
KR (1) KR100939216B1 (en)
WO (1) WO2009075516A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584790B (en) * 2011-12-31 2014-04-02 江苏奥赛康药业股份有限公司 S-pantoprazole sodium trihydrate, and preparation method and application thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006514108A (en) 2002-12-19 2006-04-27 テバ ファーマシューティカル インダストリーズ リミティド Solid state of pantoprazole sodium, process for preparing them, and process for preparing known pantoprazole sodium hydrate
CN103467451A (en) * 2012-06-07 2013-12-25 上海汇伦生命科技有限公司 Preparation method for S-pantoprazole sodium
EP3397630B1 (en) * 2015-12-30 2021-05-26 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of pantoprazole sodium sesquihydrate
EP3187494A1 (en) * 2015-12-30 2017-07-05 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of pantoprazole sodium sesquihydrate
CN113461664A (en) * 2020-03-30 2021-10-01 北京新领先医药科技发展有限公司 Method for preparing pantoprazole sodium sesquihydrate

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6933389B2 (en) * 2002-09-02 2005-08-23 Dr. Reddy's Laboratories Limited Process for preparation of crystalline form-1 of pantoprazole sodium sesquihydrate
US7081534B2 (en) * 2003-09-23 2006-07-25 Dipharma S.P.A. Process for the preparation of pantoprazole and salts thereof
EP1795530A1 (en) * 2002-12-19 2007-06-13 Teva Pharmaceutical Industries Limited Process for preparing known pantoprazole sodium sesquihydrate

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006514108A (en) 2002-12-19 2006-04-27 テバ ファーマシューティカル インダストリーズ リミティド Solid state of pantoprazole sodium, process for preparing them, and process for preparing known pantoprazole sodium hydrate
WO2007017890A2 (en) * 2005-05-04 2007-02-15 Rpg Life Sciences Limited Process for preparation of pantoprazole sodium sesquihydrate and product prepared therby
KR101170940B1 (en) * 2005-06-25 2012-08-03 에이치 엘 지노믹스(주) A process for preparing a crystalline pantoprazole sodium sesquihydrate

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6933389B2 (en) * 2002-09-02 2005-08-23 Dr. Reddy's Laboratories Limited Process for preparation of crystalline form-1 of pantoprazole sodium sesquihydrate
EP1795530A1 (en) * 2002-12-19 2007-06-13 Teva Pharmaceutical Industries Limited Process for preparing known pantoprazole sodium sesquihydrate
US7081534B2 (en) * 2003-09-23 2006-07-25 Dipharma S.P.A. Process for the preparation of pantoprazole and salts thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102584790B (en) * 2011-12-31 2014-04-02 江苏奥赛康药业股份有限公司 S-pantoprazole sodium trihydrate, and preparation method and application thereof

Also Published As

Publication number Publication date
WO2009075516A2 (en) 2009-06-18
KR20090061127A (en) 2009-06-16
KR100939216B1 (en) 2010-01-28

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