PL2123276T3 - Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji - Google Patents
Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacjiInfo
- Publication number
- PL2123276T3 PL2123276T3 PL08711267T PL08711267T PL2123276T3 PL 2123276 T3 PL2123276 T3 PL 2123276T3 PL 08711267 T PL08711267 T PL 08711267T PL 08711267 T PL08711267 T PL 08711267T PL 2123276 T3 PL2123276 T3 PL 2123276T3
- Authority
- PL
- Poland
- Prior art keywords
- pyrazine derivative
- combination
- pharmaceutical composition
- pyrazine
- derivative
- Prior art date
Links
- 150000003216 pyrazines Chemical class 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Emergency Medicine (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007035975 | 2007-02-16 | ||
| EP08711267A EP2123276B1 (en) | 2007-02-16 | 2008-02-14 | Pharmaceutical composition comprising pyrazine derivative, and method of using pyrazine derivative in combination |
| PCT/JP2008/052425 WO2008099874A1 (ja) | 2007-02-16 | 2008-02-14 | ピラジン誘導体を含有する医薬組成物およびピラジン誘導体を組み合わせて使用する方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2123276T3 true PL2123276T3 (pl) | 2013-04-30 |
Family
ID=39690101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08711267T PL2123276T3 (pl) | 2007-02-16 | 2008-02-14 | Kompozycja farmaceutyczna zawierająca pochodną pirazyny oraz sposób stosowania pochodnej pirazyny w kombinacji |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8759354B2 (pl) |
| EP (1) | EP2123276B1 (pl) |
| JP (1) | JP5255456B2 (pl) |
| KR (1) | KR101479083B1 (pl) |
| CN (1) | CN101610772B (pl) |
| AU (1) | AU2008215397B2 (pl) |
| BR (1) | BRPI0807597B8 (pl) |
| CA (1) | CA2677905C (pl) |
| CY (1) | CY1113435T1 (pl) |
| DK (1) | DK2123276T3 (pl) |
| ES (1) | ES2396595T3 (pl) |
| HR (1) | HRP20130111T1 (pl) |
| IL (1) | IL200285A (pl) |
| MX (1) | MX2009008779A (pl) |
| NZ (1) | NZ578989A (pl) |
| PL (1) | PL2123276T3 (pl) |
| PT (1) | PT2123276E (pl) |
| RU (1) | RU2463051C2 (pl) |
| SI (1) | SI2123276T1 (pl) |
| WO (1) | WO2008099874A1 (pl) |
| ZA (1) | ZA200905536B (pl) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010117114A1 (en) * | 2009-04-09 | 2010-10-14 | Lg Electronics Inc. | Display apparatus |
| KR101745386B1 (ko) * | 2010-05-10 | 2017-06-09 | 아카데미아 시니카 | 항-인플루엔자 활성을 가진 자나미비르 포스포네이트 동족체 및 인플루엔자 바이러스의 오셀타미비르 감수성을 확인하는 방법 |
| RS54408B1 (en) | 2010-09-30 | 2016-04-28 | Toyama Chemical Co. Ltd. | SODIUM SO 6-FLUOR-3-HYDROXY-2-PYRAZINE CARBOXAMIDE |
| EP2623497B1 (en) | 2010-09-30 | 2016-01-20 | Toyama Chemical Co., Ltd. | Meglumine salt of 6-fluoro-3-hydroxy-2-pyrazine carboxamide |
| AT510585B1 (de) * | 2010-11-18 | 2012-05-15 | Apeptico Forschung & Entwicklung Gmbh | Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase |
| JP6417568B2 (ja) * | 2013-05-14 | 2018-11-07 | バイオクリスト ファーマスーティカルズ，インコーポレイテッドＢｉｏｃｒｙｓｔ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． | 抗インフルエンザ組成物及び方法 |
| CN104447585B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 吡嗪类化合物及其组合物及用途 |
| CN104447584B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104402833B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104447583B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104496918B (zh) * | 2014-12-10 | 2016-08-24 | 广东东阳光药业有限公司 | 吡嗪衍生物及其用途 |
| CN104817511B (zh) * | 2015-04-27 | 2017-04-19 | 济南大学 | 一种丁烯二酸酐制备法匹拉韦关键中间体的方法 |
| SG10201911957QA (en) * | 2015-12-15 | 2020-02-27 | Shionogi & Co | Medicine for treating influenza characterized by comprising combination of cap-dependent endonuclease inhibitor with anti-influenza drug |
| US20220096468A1 (en) | 2018-12-25 | 2022-03-31 | Fujifilm Toyama Chemical Co., Ltd. | Therapeutic agent for RNA viral infection comprising a combination of pyrazine derivative and compound which increases amount of pyrazine derivative ribose triphosphate in cell |
| JP7449379B2 (ja) | 2020-05-27 | 2024-03-13 | 富士フイルム富山化学株式会社 | ピラジン誘導体とチオプリン誘導体を組み合わせてなるｒｎａウイルス感染症治療剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01197437A (ja) * | 1988-01-29 | 1989-08-09 | Dso Pharmachim | 抗ウイルス薬 |
| CN1275947C (zh) * | 1998-08-20 | 2006-09-20 | 富山化学工业株式会社 | 含氮杂环羧酰胺衍生物或其盐 |
| BR0211900A (pt) * | 2001-08-14 | 2004-08-24 | Toyama Chemical Co Ltd | Método para inibição do desenvolvimento de vìrus e/ou virucida, análogos de nucleotìdeo de pirazina e de nucleosìdeo de pirazina, precursor do inibidor da polimerase de rna, inibidor da polimerase de rna, método para tratar pacientes infectados por vìrus, e, usos de um análogo de nucleotìdeo de pirazina ou um sal deste e de um análogo de nucleosìdeo de pirazina ou um sal deste |
| JP2005354833A (ja) * | 2004-06-11 | 2005-12-22 | Fujinon Corp | アクチュエータ |
| JP4689989B2 (ja) * | 2004-08-27 | 2011-06-01 | オリンパス株式会社 | 振動波リニアモータ及びそれを用いたレンズ装置 |
| DE102008031715A1 (de) | 2008-07-04 | 2010-01-07 | Henkel Ag & Co. Kgaa | Haarkonditionierende Mittel mit Imidazolinen |
-
2008
- 2008-02-14 NZ NZ578989A patent/NZ578989A/en unknown
- 2008-02-14 MX MX2009008779A patent/MX2009008779A/es active IP Right Grant
- 2008-02-14 JP JP2008558114A patent/JP5255456B2/ja active Active
- 2008-02-14 ZA ZA200905536A patent/ZA200905536B/xx unknown
- 2008-02-14 EP EP08711267A patent/EP2123276B1/en active Active
- 2008-02-14 SI SI200830895T patent/SI2123276T1/sl unknown
- 2008-02-14 DK DK08711267.8T patent/DK2123276T3/da active
- 2008-02-14 PL PL08711267T patent/PL2123276T3/pl unknown
- 2008-02-14 AU AU2008215397A patent/AU2008215397B2/en active Active
- 2008-02-14 BR BRPI0807597A patent/BRPI0807597B8/pt active IP Right Grant
- 2008-02-14 WO PCT/JP2008/052425 patent/WO2008099874A1/ja active Application Filing
- 2008-02-14 CA CA2677905A patent/CA2677905C/en active Active
- 2008-02-14 KR KR20097017506A patent/KR101479083B1/ko active IP Right Grant
- 2008-02-14 RU RU2009134516/15A patent/RU2463051C2/ru active
- 2008-02-14 PT PT87112678T patent/PT2123276E/pt unknown
- 2008-02-14 CN CN200880005061XA patent/CN101610772B/zh active Active
- 2008-02-14 ES ES08711267T patent/ES2396595T3/es active Active
- 2008-02-14 US US12/527,260 patent/US8759354B2/en active Active
-
2009
- 2009-08-06 IL IL200285A patent/IL200285A/en not_active IP Right Cessation
-
2012
- 2012-12-03 CY CY20121101175T patent/CY1113435T1/el unknown
-
2013
- 2013-02-07 HR HRP20130111AT patent/HRP20130111T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2123276B1 (en) | 2012-11-28 |
| CY1113435T1 (el) | 2016-06-22 |
| IL200285A0 (en) | 2010-04-29 |
| WO2008099874A1 (ja) | 2008-08-21 |
| KR20090121289A (ko) | 2009-11-25 |
| DK2123276T3 (da) | 2013-01-02 |
| KR101479083B1 (ko) | 2015-01-07 |
| MX2009008779A (es) | 2009-11-05 |
| NZ578989A (en) | 2011-07-29 |
| ES2396595T3 (es) | 2013-02-22 |
| EP2123276A4 (en) | 2011-05-18 |
| BRPI0807597B8 (pt) | 2021-05-25 |
| CN101610772A (zh) | 2009-12-23 |
| IL200285A (en) | 2014-06-30 |
| SI2123276T1 (sl) | 2013-03-29 |
| AU2008215397B2 (en) | 2012-09-06 |
| US20100087447A1 (en) | 2010-04-08 |
| HRP20130111T1 (hr) | 2013-02-28 |
| AU2008215397A1 (en) | 2008-08-21 |
| JPWO2008099874A1 (ja) | 2010-05-27 |
| CA2677905C (en) | 2015-03-24 |
| JP5255456B2 (ja) | 2013-08-07 |
| EP2123276A1 (en) | 2009-11-25 |
| PT2123276E (pt) | 2013-01-16 |
| US8759354B2 (en) | 2014-06-24 |
| CN101610772B (zh) | 2013-01-16 |
| BRPI0807597A2 (pt) | 2014-05-06 |
| CA2677905A1 (en) | 2008-08-21 |
| ZA200905536B (en) | 2010-10-27 |
| RU2009134516A (ru) | 2011-03-27 |
| RU2463051C2 (ru) | 2012-10-10 |
| BRPI0807597B1 (pt) | 2021-03-02 |
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