PT2123276E - Composição farmacêutica que contem um derivado de pirazina, e processo de utilização de um derivado de pirazina em associação - Google Patents
Composição farmacêutica que contem um derivado de pirazina, e processo de utilização de um derivado de pirazina em associaçãoInfo
- Publication number
- PT2123276E PT2123276E PT87112678T PT08711267T PT2123276E PT 2123276 E PT2123276 E PT 2123276E PT 87112678 T PT87112678 T PT 87112678T PT 08711267 T PT08711267 T PT 08711267T PT 2123276 E PT2123276 E PT 2123276E
- Authority
- PT
- Portugal
- Prior art keywords
- pyrazine derivative
- combination
- pharmaceutical composition
- pyrazine
- derivative
- Prior art date
Links
- 150000003216 pyrazines Chemical class 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007035975 | 2007-02-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2123276E true PT2123276E (pt) | 2013-01-16 |
Family
ID=39690101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87112678T PT2123276E (pt) | 2007-02-16 | 2008-02-14 | Composição farmacêutica que contem um derivado de pirazina, e processo de utilização de um derivado de pirazina em associação |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8759354B2 (pt) |
| EP (1) | EP2123276B1 (pt) |
| JP (1) | JP5255456B2 (pt) |
| KR (1) | KR101479083B1 (pt) |
| CN (1) | CN101610772B (pt) |
| AU (1) | AU2008215397B2 (pt) |
| BR (1) | BRPI0807597B8 (pt) |
| CA (1) | CA2677905C (pt) |
| CY (1) | CY1113435T1 (pt) |
| DK (1) | DK2123276T3 (pt) |
| ES (1) | ES2396595T3 (pt) |
| HR (1) | HRP20130111T1 (pt) |
| IL (1) | IL200285A (pt) |
| MX (1) | MX2009008779A (pt) |
| NZ (1) | NZ578989A (pt) |
| PL (1) | PL2123276T3 (pt) |
| PT (1) | PT2123276E (pt) |
| RU (1) | RU2463051C2 (pt) |
| SI (1) | SI2123276T1 (pt) |
| WO (1) | WO2008099874A1 (pt) |
| ZA (1) | ZA200905536B (pt) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2417617A4 (en) * | 2009-04-09 | 2012-09-26 | Lg Electronics Inc | DISPLAY APPARATUS |
| CN104777301B (zh) * | 2010-05-10 | 2018-04-20 | 中央研究院 | 具有抗流感活性的扎那米韦膦酸酯同类物及流感病毒的奥司他韦易感性的测定 |
| PL2623498T3 (pl) * | 2010-09-30 | 2016-05-31 | Toyama Chemical Co Ltd | Sól sodowa 6-fluoro-3-hydroksy-2-pirazynokarboksamidu |
| HUE026794T2 (en) | 2010-09-30 | 2016-07-28 | Toyama Chemical Co Ltd | The oleum salt of 6-fluoro-3-hydroxy-2-pyrazinecarboxamide |
| AT510585B1 (de) | 2010-11-18 | 2012-05-15 | Apeptico Forschung & Entwicklung Gmbh | Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase |
| WO2014186465A1 (en) * | 2013-05-14 | 2014-11-20 | Biocryst Pharmaceuticals, Inc. | Anti-influenza compositions and methods |
| CN104402833B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104447585B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 吡嗪类化合物及其组合物及用途 |
| CN104447583B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104447584B (zh) * | 2014-11-20 | 2016-08-24 | 广东东阳光药业有限公司 | 含有环丁烷取代基的吡嗪类化合物及其组合物及用途 |
| CN104496918B (zh) * | 2014-12-10 | 2016-08-24 | 广东东阳光药业有限公司 | 吡嗪衍生物及其用途 |
| CN104817511B (zh) * | 2015-04-27 | 2017-04-19 | 济南大学 | 一种丁烯二酸酐制备法匹拉韦关键中间体的方法 |
| RU2745071C2 (ru) * | 2015-12-15 | 2021-03-18 | Сионоги Энд Ко., Лтд. | Лекарственный препарат для лечения гриппа, характеризующийся тем, что в нем объединены ингибитор кэп-зависимой эндонуклеазы и лекарственное средство против гриппа |
| WO2020138067A1 (ja) | 2018-12-25 | 2020-07-02 | 富士フイルム富山化学株式会社 | ピラジン誘導体と細胞内におけるピラジン誘導体リボース三リン酸体の量を増加させる化合物とを組み合わせてなるｒｎａウイルス感染症治療剤 |
| JP7449379B2 (ja) | 2020-05-27 | 2024-03-13 | 富士フイルム富山化学株式会社 | ピラジン誘導体とチオプリン誘導体を組み合わせてなるｒｎａウイルス感染症治療剤 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01197437A (ja) * | 1988-01-29 | 1989-08-09 | Dso Pharmachim | 抗ウイルス薬 |
| BRPI9913097B8 (pt) * | 1998-08-20 | 2021-05-25 | Fujifilm Toyama Chemical Co Ltd | derivado heterocíclico de carboxamida contendo nitrogênio ou um sal do mesmo |
| WO2003015798A1 (en) | 2001-08-14 | 2003-02-27 | Toyama Chemical Co., Ltd. | Novel virus proliferation inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue |
| JP2005354833A (ja) * | 2004-06-11 | 2005-12-22 | Fujinon Corp | アクチュエータ |
| JP4689989B2 (ja) * | 2004-08-27 | 2011-06-01 | オリンパス株式会社 | 振動波リニアモータ及びそれを用いたレンズ装置 |
| DE102008031715A1 (de) | 2008-07-04 | 2010-01-07 | Henkel Ag & Co. Kgaa | Haarkonditionierende Mittel mit Imidazolinen |
-
2008
- 2008-02-14 PT PT87112678T patent/PT2123276E/pt unknown
- 2008-02-14 ZA ZA200905536A patent/ZA200905536B/xx unknown
- 2008-02-14 PL PL08711267T patent/PL2123276T3/pl unknown
- 2008-02-14 ES ES08711267T patent/ES2396595T3/es active Active
- 2008-02-14 BR BRPI0807597A patent/BRPI0807597B8/pt active IP Right Grant
- 2008-02-14 EP EP08711267A patent/EP2123276B1/en active Active
- 2008-02-14 SI SI200830895T patent/SI2123276T1/sl unknown
- 2008-02-14 CN CN200880005061XA patent/CN101610772B/zh active Active
- 2008-02-14 NZ NZ578989A patent/NZ578989A/en unknown
- 2008-02-14 DK DK08711267.8T patent/DK2123276T3/da active
- 2008-02-14 AU AU2008215397A patent/AU2008215397B2/en active Active
- 2008-02-14 MX MX2009008779A patent/MX2009008779A/es active IP Right Grant
- 2008-02-14 RU RU2009134516/15A patent/RU2463051C2/ru active
- 2008-02-14 KR KR20097017506A patent/KR101479083B1/ko active IP Right Grant
- 2008-02-14 JP JP2008558114A patent/JP5255456B2/ja active Active
- 2008-02-14 WO PCT/JP2008/052425 patent/WO2008099874A1/ja active Application Filing
- 2008-02-14 US US12/527,260 patent/US8759354B2/en active Active
- 2008-02-14 CA CA2677905A patent/CA2677905C/en active Active
-
2009
- 2009-08-06 IL IL200285A patent/IL200285A/en not_active IP Right Cessation
-
2012
- 2012-12-03 CY CY20121101175T patent/CY1113435T1/el unknown
-
2013
- 2013-02-07 HR HRP20130111AT patent/HRP20130111T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5255456B2 (ja) | 2013-08-07 |
| US8759354B2 (en) | 2014-06-24 |
| PL2123276T3 (pl) | 2013-04-30 |
| RU2463051C2 (ru) | 2012-10-10 |
| JPWO2008099874A1 (ja) | 2010-05-27 |
| KR101479083B1 (ko) | 2015-01-07 |
| IL200285A0 (en) | 2010-04-29 |
| US20100087447A1 (en) | 2010-04-08 |
| EP2123276B1 (en) | 2012-11-28 |
| HRP20130111T1 (hr) | 2013-02-28 |
| ES2396595T3 (es) | 2013-02-22 |
| ZA200905536B (en) | 2010-10-27 |
| KR20090121289A (ko) | 2009-11-25 |
| WO2008099874A1 (ja) | 2008-08-21 |
| CN101610772B (zh) | 2013-01-16 |
| CN101610772A (zh) | 2009-12-23 |
| SI2123276T1 (sl) | 2013-03-29 |
| CA2677905A1 (en) | 2008-08-21 |
| RU2009134516A (ru) | 2011-03-27 |
| AU2008215397B2 (en) | 2012-09-06 |
| EP2123276A1 (en) | 2009-11-25 |
| CY1113435T1 (el) | 2016-06-22 |
| IL200285A (en) | 2014-06-30 |
| BRPI0807597B8 (pt) | 2021-05-25 |
| BRPI0807597B1 (pt) | 2021-03-02 |
| DK2123276T3 (da) | 2013-01-02 |
| CA2677905C (en) | 2015-03-24 |
| EP2123276A4 (en) | 2011-05-18 |
| MX2009008779A (es) | 2009-11-05 |
| NZ578989A (en) | 2011-07-29 |
| BRPI0807597A2 (pt) | 2014-05-06 |
| AU2008215397A1 (en) | 2008-08-21 |
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