PL207877B1 - Sól acetylo L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania - Google Patents
Sól acetylo L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywaniaInfo
- Publication number
- PL207877B1 PL207877B1 PL371130A PL37113002A PL207877B1 PL 207877 B1 PL207877 B1 PL 207877B1 PL 371130 A PL371130 A PL 371130A PL 37113002 A PL37113002 A PL 37113002A PL 207877 B1 PL207877 B1 PL 207877B1
- Authority
- PL
- Poland
- Prior art keywords
- acetyl
- carnitine
- fumarate
- crystalline
- solution
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2001RM000729A ITRM20010729A1 (it) | 2001-12-12 | 2001-12-12 | Sale di acetil l-carnitina con un acido organico dicarbossilico e procedimento per la sua preparazione. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL371130A1 PL371130A1 (en) | 2005-06-13 |
| PL207877B1 true PL207877B1 (pl) | 2011-02-28 |
Family
ID=11455916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL371130A PL207877B1 (pl) | 2001-12-12 | 2002-11-25 | Sól acetylo L-karnityny z organicznymi kwasami dikarboksylowymi oraz metody jej otrzymywania |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6673837B2 (enExample) |
| EP (1) | EP1453791B1 (enExample) |
| JP (1) | JP4902940B2 (enExample) |
| KR (1) | KR100860386B1 (enExample) |
| CN (1) | CN1250521C (enExample) |
| AT (1) | ATE457300T1 (enExample) |
| AU (1) | AU2002358989A1 (enExample) |
| CA (1) | CA2468234C (enExample) |
| CY (1) | CY1110684T1 (enExample) |
| DE (1) | DE60235318D1 (enExample) |
| DK (1) | DK1453791T3 (enExample) |
| ES (1) | ES2339432T3 (enExample) |
| HU (1) | HU230034B1 (enExample) |
| IT (1) | ITRM20010729A1 (enExample) |
| PL (1) | PL207877B1 (enExample) |
| PT (1) | PT1453791E (enExample) |
| SI (1) | SI1453791T1 (enExample) |
| WO (1) | WO2003053911A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
| CN101209975B (zh) * | 2006-12-29 | 2010-12-01 | 沈阳科硕营养科技有限公司 | 左旋肉碱富马酸钙及其制备方法与用途 |
| US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
| JP2012092036A (ja) * | 2010-10-26 | 2012-05-17 | Mitsubishi Rayon Co Ltd | カルニチンの塩の製造方法 |
| JP2014525324A (ja) * | 2011-08-31 | 2014-09-29 | ザ プロクター アンド ギャンブル カンパニー | 接着された強化層を有するファスニング部材 |
| JP5933383B2 (ja) * | 2012-07-26 | 2016-06-08 | ロート製薬株式会社 | 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法 |
| JP6100939B2 (ja) * | 2016-02-26 | 2017-03-22 | ロート製薬株式会社 | 内服用固形製剤の吸湿性・流動性の改善方法、吸湿性・流動性が改善されてなる内服用固形製剤、及び該内服用固形製剤の製造法 |
| JP6964876B2 (ja) * | 2017-11-27 | 2021-11-10 | 株式会社古川リサーチオフィス | オロット酸−カルニチン混合体粉体又はフマル酸−カルニチン混合体粉体の製造方法 |
| CN119351483B (zh) * | 2024-12-03 | 2025-05-30 | 北京佰依源生物科技有限公司 | 一种长碳链二元酸生产强度提高的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0150688B1 (en) * | 1983-12-28 | 1987-04-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same |
-
2001
- 2001-12-12 IT IT2001RM000729A patent/ITRM20010729A1/it unknown
-
2002
- 2002-07-31 US US10/207,993 patent/US6673837B2/en not_active Expired - Lifetime
- 2002-11-25 DE DE60235318T patent/DE60235318D1/de not_active Expired - Lifetime
- 2002-11-25 EP EP02793335A patent/EP1453791B1/en not_active Expired - Lifetime
- 2002-11-25 PT PT02793335T patent/PT1453791E/pt unknown
- 2002-11-25 CA CA2468234A patent/CA2468234C/en not_active Expired - Fee Related
- 2002-11-25 PL PL371130A patent/PL207877B1/pl unknown
- 2002-11-25 ES ES02793335T patent/ES2339432T3/es not_active Expired - Lifetime
- 2002-11-25 WO PCT/IT2002/000743 patent/WO2003053911A1/en not_active Ceased
- 2002-11-25 AT AT02793335T patent/ATE457300T1/de active
- 2002-11-25 JP JP2003554628A patent/JP4902940B2/ja not_active Expired - Fee Related
- 2002-11-25 AU AU2002358989A patent/AU2002358989A1/en not_active Abandoned
- 2002-11-25 SI SI200230893T patent/SI1453791T1/sl unknown
- 2002-11-25 KR KR1020047008307A patent/KR100860386B1/ko not_active Expired - Fee Related
- 2002-11-25 DK DK02793335.7T patent/DK1453791T3/da active
- 2002-11-25 HU HU0402545A patent/HU230034B1/hu not_active IP Right Cessation
- 2002-11-25 CN CNB028248260A patent/CN1250521C/zh not_active Expired - Fee Related
-
2010
- 2010-04-27 CY CY20101100377T patent/CY1110684T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1602294A (zh) | 2005-03-30 |
| KR20040064721A (ko) | 2004-07-19 |
| HU230034B1 (hu) | 2015-05-28 |
| WO2003053911A1 (en) | 2003-07-03 |
| JP2005513122A (ja) | 2005-05-12 |
| HK1073295A1 (en) | 2005-09-30 |
| HUP0402545A3 (en) | 2012-09-28 |
| ITRM20010729A1 (it) | 2003-06-12 |
| JP4902940B2 (ja) | 2012-03-21 |
| DK1453791T3 (da) | 2010-05-25 |
| PL371130A1 (en) | 2005-06-13 |
| HUP0402545A2 (hu) | 2005-04-28 |
| ATE457300T1 (de) | 2010-02-15 |
| EP1453791B1 (en) | 2010-02-10 |
| PT1453791E (pt) | 2010-04-14 |
| CY1110684T1 (el) | 2015-06-10 |
| CN1250521C (zh) | 2006-04-12 |
| SI1453791T1 (sl) | 2010-11-30 |
| US20030119904A1 (en) | 2003-06-26 |
| DE60235318D1 (de) | 2010-03-25 |
| CA2468234A1 (en) | 2003-07-03 |
| CA2468234C (en) | 2010-02-23 |
| US6673837B2 (en) | 2004-01-06 |
| ES2339432T3 (es) | 2010-05-20 |
| AU2002358989A1 (en) | 2003-07-09 |
| KR100860386B1 (ko) | 2008-09-26 |
| EP1453791A1 (en) | 2004-09-08 |
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