PL1994005T3 - Pochodne tetrahydronaftalenu, procesy ich wytwarzania i ich zastosowanie jako środków przeciwzapalnych - Google Patents
Pochodne tetrahydronaftalenu, procesy ich wytwarzania i ich zastosowanie jako środków przeciwzapalnychInfo
- Publication number
- PL1994005T3 PL1994005T3 PL07723399T PL07723399T PL1994005T3 PL 1994005 T3 PL1994005 T3 PL 1994005T3 PL 07723399 T PL07723399 T PL 07723399T PL 07723399 T PL07723399 T PL 07723399T PL 1994005 T3 PL1994005 T3 PL 1994005T3
- Authority
- PL
- Poland
- Prior art keywords
- tetrahydronaphthaline
- derivatives
- production
- methods
- inflammatory agents
- Prior art date
Links
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- CXWXQJXEFPUFDZ-UHFFFAOYSA-N tetralin Chemical class C1=CC=C2CCCCC2=C1 CXWXQJXEFPUFDZ-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/20—Polycyclic condensed hydrocarbons
- C07C15/24—Polycyclic condensed hydrocarbons containing two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
- C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06090031A EP1834948A1 (de) | 2006-03-15 | 2006-03-15 | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US78444106P | 2006-03-22 | 2006-03-22 | |
| EP07723399A EP1994005B9 (de) | 2006-03-15 | 2007-03-15 | Tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
| PCT/EP2007/002432 WO2007104582A1 (de) | 2006-03-15 | 2007-03-15 | Tetrahydronaphthalinderivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1994005T3 true PL1994005T3 (pl) | 2012-01-31 |
Family
ID=36754173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL07723399T PL1994005T3 (pl) | 2006-03-15 | 2007-03-15 | Pochodne tetrahydronaftalenu, procesy ich wytwarzania i ich zastosowanie jako środków przeciwzapalnych |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US7880042B2 (pl) |
| EP (2) | EP1834948A1 (pl) |
| JP (1) | JP2009532337A (pl) |
| KR (1) | KR20080112233A (pl) |
| CN (1) | CN101553472A (pl) |
| AR (1) | AR059896A1 (pl) |
| AT (1) | ATE517092T1 (pl) |
| AU (1) | AU2007224593A1 (pl) |
| BR (1) | BRPI0708860A2 (pl) |
| CA (1) | CA2637597A1 (pl) |
| CR (1) | CR10286A (pl) |
| CU (1) | CU23744B7 (pl) |
| CY (1) | CY1111954T1 (pl) |
| DK (1) | DK1994005T3 (pl) |
| DO (1) | DOP2007000050A (pl) |
| EA (1) | EA015834B1 (pl) |
| EC (1) | ECSP088740A (pl) |
| ES (1) | ES2370176T3 (pl) |
| GT (1) | GT200800182A (pl) |
| IL (1) | IL193155A0 (pl) |
| MX (1) | MX2008011790A (pl) |
| MY (1) | MY146671A (pl) |
| NO (1) | NO20084301L (pl) |
| NZ (1) | NZ570407A (pl) |
| PA (1) | PA8718801A1 (pl) |
| PE (1) | PE20071024A1 (pl) |
| PL (1) | PL1994005T3 (pl) |
| PT (1) | PT1994005E (pl) |
| SG (1) | SG136072A1 (pl) |
| SI (1) | SI1994005T1 (pl) |
| TW (1) | TW200804287A (pl) |
| UA (1) | UA94603C2 (pl) |
| UY (1) | UY30211A1 (pl) |
| WO (1) | WO2007104582A1 (pl) |
| ZA (1) | ZA200808754B (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7638515B2 (en) * | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| EA010186B1 (ru) * | 2003-10-08 | 2008-06-30 | Шеринг Акциенгезельшафт | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств |
| US20080153859A1 (en) * | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20060084652A1 (en) * | 2004-09-09 | 2006-04-20 | Stefan Baeurle | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20060229305A1 (en) * | 2005-03-22 | 2006-10-12 | Markus Berger | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| EP2072509A1 (en) * | 2007-12-18 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents |
| WO2011146610A2 (en) * | 2010-05-19 | 2011-11-24 | Dr. Reddy's Laboratories Ltd. | An enantioselective synthesis of chiral amines for the production of rotigotine |
| JP6115303B2 (ja) * | 2012-05-18 | 2017-04-19 | Jnc株式会社 | 隣接基としてカルボニル基を有するフェノール化合物およびその用途 |
| PL233977B1 (pl) * | 2018-01-10 | 2019-12-31 | Politechnika Warszawska | Sposób otrzymywania 7-metoksy-1,2,3-tris(4-metoksyfenylo)- 1,2,3,4-tetrahydronaftalenu |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791474A (fr) | 1971-11-25 | 1973-03-16 | Yamanouchi Pharma Co Ltd | Procede de preparation de derives d'acides cycloalcoylaminoarylcarboxyliques |
| JPS63220242A (ja) | 1987-03-10 | 1988-09-13 | Fuji Photo Film Co Ltd | フオトレジスト組成物 |
| US5225436A (en) | 1987-05-15 | 1993-07-06 | Schering Corporation | Aryl substituted naphthalene derivatives |
| AU617672B2 (en) | 1987-05-15 | 1991-12-05 | Schering Corporation | Aryl substituted naphthalene, benzoxepine, benzazepine, benzocycloheptene derivatives |
| US5112834A (en) | 1987-07-16 | 1992-05-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Imidazole protectorant for the stomach and intestine |
| US5059609A (en) | 1987-10-19 | 1991-10-22 | Pfizer Inc. | Substituted tetralins, chromans and related compounds in the treatment of asthma, arthritis and related diseases |
| JPH0717589B2 (ja) | 1990-01-22 | 1995-03-01 | ファイザー製薬株式会社 | 新規１，３―ジカルボニル化合物およびその組成物 |
| JPH0641038A (ja) | 1992-07-17 | 1994-02-15 | Mitsubishi Kasei Corp | カルボン酸誘導体 |
| US5489584A (en) | 1994-12-29 | 1996-02-06 | Allergan, Inc. | Acetylenes disubstituted with a 5-amino or substituted 5-amino substituted tetrahydronaphthyl group and with an aryl or heteroaryl group having retinoid-like biological activity |
| CA2208844A1 (en) | 1994-12-29 | 1996-07-11 | Alan T. Johnson | Acetylenes disubstituted with a 5 or 8 substituted tetrahydronaphthyl or dihydronaphthyl group and with an aryl or heteroaryl groups having retinoid-like biological activity |
| UA61102C2 (uk) | 1997-03-24 | 2003-11-17 | Бік Гульден Ломберг Хеміше Фабрік Гмбх | Сполука тетрагідропіридину та лікарський засіб на її основі |
| CA2297906A1 (en) | 1997-07-22 | 1999-02-04 | Bret Eugene Huff | Pharmaceutical compounds |
| GB9716244D0 (en) | 1997-07-31 | 1997-10-08 | Electrophoretics International | Pharmaceutical compounds |
| US6333337B1 (en) | 1998-01-27 | 2001-12-25 | Icagen, Inc. | Potassium channel inhibitors |
| US7468422B2 (en) * | 1998-03-05 | 2008-12-23 | Centre National De La Recherche Scientifique - Cnrs | Mechanosensitive mammalian potassium channel activatable by polyunsaturated fatty acids |
| US6013830A (en) | 1998-03-30 | 2000-01-11 | Sepracor Inc. | Asymmetric grignard synthesis with cyclic 1,2 aminoalcohols |
| AU5682299A (en) | 1998-08-21 | 2000-03-14 | Scripps Research Institute, The | Catalytic asymmetric aminohydroxylation with amino-substituted heterocycles |
| JP2000256255A (ja) | 1999-03-10 | 2000-09-19 | Kuraray Co Ltd | （±）−トランス−ペルメトリン酸の光学分割法 |
| SE9903930D0 (sv) | 1999-10-29 | 1999-10-29 | Astra Pharma Inc | Novel compounds and a novel process for their preparation |
| DE10038639A1 (de) | 2000-07-28 | 2002-02-21 | Schering Ag | Nichtsteroidale Entzündungshemmer |
| AU8022901A (en) | 2000-08-21 | 2002-03-04 | Pacific Corp | Novel thiourea derivatives and the pharmaceutical compositions containing the same |
| ES2193839B1 (es) | 2001-06-22 | 2005-02-16 | Almirall Prodesfarma, S.A. | Nuevos derivados de 6-fenildihidropirrolpirimidindiona. |
| EP1436249B1 (en) | 2001-09-21 | 2013-11-06 | Eli Lilly And Company | Muscarinic agonists |
| GT200200188A (es) | 2001-09-24 | 2003-06-25 | Preparacion y uso de derivados de imidazol para el tratamiento de la obesidad | |
| CA2467870A1 (en) | 2001-11-21 | 2003-06-05 | Pharmacia & Upjohn Company | Substituted aryl 1,4-pyrazine derivatives |
| US6875866B2 (en) | 2002-02-21 | 2005-04-05 | Schering Corporation | Process for synthesis of D1 receptor antagonists |
| EP1497300A2 (en) | 2002-03-21 | 2005-01-19 | Schering Aktiengesellschaft | Plasma carboxypeptidase b inhibitors |
| MXPA04009329A (es) | 2002-03-26 | 2005-01-25 | Boehringer Ingelheim Pharma | Mimeticos de glucocorticoides, metodos para su preparacion, composiciones farmaceuticas y usos de los mismos. |
| US6897224B2 (en) | 2002-04-02 | 2005-05-24 | Schering Ag | Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors |
| DE10215316C1 (de) | 2002-04-02 | 2003-12-18 | Schering Ag | Chinolin- und Isochinolin-Derivate, ein pharmazeutisches Mittel und ihre Verwendung als Entzündungshemmer |
| US7291366B2 (en) | 2002-08-26 | 2007-11-06 | Merck Patent Gmbh | Cyclopenta[b]naphthalene derivatives |
| US7579469B2 (en) | 2003-01-03 | 2009-08-25 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US20040224992A1 (en) | 2003-02-27 | 2004-11-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| WO2005003098A1 (de) | 2003-07-01 | 2005-01-13 | Schering Aktiengesellschaft | Heterozyklisch substituierte pentanol-derivate, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer |
| US20050090559A1 (en) | 2003-07-01 | 2005-04-28 | Markus Berger | Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004037387B4 (de) | 2003-08-22 | 2014-11-20 | Merck Patent Gmbh | Cyclopenta[a]naphthalinderivate |
| CN1239441C (zh) | 2003-09-12 | 2006-02-01 | 中国科学院上海有机化学研究所 | 利用固载化的双辛可尼类生物碱配体催化不对称羟胺化和双羟化反应的方法 |
| US7638515B2 (en) * | 2003-10-08 | 2009-12-29 | Bayer Schering Pharma Aktiengesellschaft | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| EA010186B1 (ru) | 2003-10-08 | 2008-06-30 | Шеринг Акциенгезельшафт | Производные тетрагидронафталина, способ их получения и их применение в качестве противовоспалительных средств |
| US7662821B2 (en) | 2003-10-08 | 2010-02-16 | Bayer Schering Pharma Ag | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US7179919B2 (en) | 2004-03-18 | 2007-02-20 | Boehringer Ingelheim Pharmaceuticals, Inc. | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
| US20080153859A1 (en) | 2004-04-05 | 2008-06-26 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20050222154A1 (en) | 2004-04-05 | 2005-10-06 | Hartmut Rehwinkel | Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
| DE102004044680B3 (de) | 2004-09-09 | 2006-06-08 | Schering Ag | Alkyliden-Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer sowie diese enthaltende pharmazeutische Präparate |
| US20060084652A1 (en) | 2004-09-09 | 2006-04-20 | Stefan Baeurle | Alkylidene-tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102004063227A1 (de) | 2004-12-22 | 2006-07-06 | Schering Ag | Tricylische Aminoalkohole, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US20060167025A1 (en) | 2004-12-22 | 2006-07-27 | Markus Berger | Tricyclic amino alcohols, processes for synthesis of same and use of same as anti-inflammatory drugs |
| US20060229305A1 (en) | 2005-03-22 | 2006-10-12 | Markus Berger | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20060247292A1 (en) * | 2005-03-22 | 2006-11-02 | Hartmut Rehwinkel | Benzocycloheptene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102005014089A1 (de) | 2005-03-22 | 2006-09-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| US20070129359A1 (en) | 2005-04-14 | 2007-06-07 | Christoph Huwe | Tetrahydronaphthalene derivatives, processes for their preparation and their use as antiinflammatory agents |
| EP1869003B1 (en) | 2005-04-14 | 2013-05-15 | Glaxo Group Limited | Indazoles as glucocorticoid receptor ligands |
| US20070015761A1 (en) | 2005-04-14 | 2007-01-18 | Anne Mengel | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| US20070015750A1 (en) | 2005-04-14 | 2007-01-18 | Stefan Baeurle | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents |
| DE102005017286B3 (de) | 2005-04-14 | 2006-12-28 | Schering Ag | Tetrahydronaphthalinderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Entzündungshemmer |
| CN101326169B (zh) | 2005-12-09 | 2011-11-16 | 霍夫曼-拉罗奇有限公司 | 作为抗炎剂的糖皮质激素受体调节剂 |
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2006
- 2006-03-15 EP EP06090031A patent/EP1834948A1/de not_active Withdrawn
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2007
- 2007-03-13 DO DO2007000050A patent/DOP2007000050A/es unknown
- 2007-03-13 PA PA20078718801A patent/PA8718801A1/es unknown
- 2007-03-14 PE PE2007000278A patent/PE20071024A1/es not_active Application Discontinuation
- 2007-03-14 SG SG200701912-8A patent/SG136072A1/en unknown
- 2007-03-14 UY UY30211A patent/UY30211A1/es not_active Application Discontinuation
- 2007-03-14 US US11/717,782 patent/US7880042B2/en not_active Expired - Fee Related
- 2007-03-14 AR ARP070101030A patent/AR059896A1/es not_active Application Discontinuation
- 2007-03-15 SI SI200730751T patent/SI1994005T1/sl unknown
- 2007-03-15 WO PCT/EP2007/002432 patent/WO2007104582A1/de active Application Filing
- 2007-03-15 DK DK07723399.7T patent/DK1994005T3/da active
- 2007-03-15 CA CA002637597A patent/CA2637597A1/en not_active Abandoned
- 2007-03-15 MX MX2008011790A patent/MX2008011790A/es active IP Right Grant
- 2007-03-15 JP JP2008558734A patent/JP2009532337A/ja active Pending
- 2007-03-15 PT PT07723399T patent/PT1994005E/pt unknown
- 2007-03-15 KR KR1020087022516A patent/KR20080112233A/ko not_active Ceased
- 2007-03-15 EP EP07723399A patent/EP1994005B9/de active Active
- 2007-03-15 AU AU2007224593A patent/AU2007224593A1/en not_active Abandoned
- 2007-03-15 PL PL07723399T patent/PL1994005T3/pl unknown
- 2007-03-15 EA EA200801893A patent/EA015834B1/ru not_active IP Right Cessation
- 2007-03-15 NZ NZ570407A patent/NZ570407A/en not_active IP Right Cessation
- 2007-03-15 CN CNA2007800091776A patent/CN101553472A/zh active Pending
- 2007-03-15 UA UAA200811918A patent/UA94603C2/ru unknown
- 2007-03-15 ES ES07723399T patent/ES2370176T3/es active Active
- 2007-03-15 TW TW096108956A patent/TW200804287A/zh unknown
- 2007-03-15 BR BRPI0708860-4A patent/BRPI0708860A2/pt not_active IP Right Cessation
- 2007-03-15 MY MYPI20083569A patent/MY146671A/en unknown
- 2007-03-15 AT AT07723399T patent/ATE517092T1/de active
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2008
- 2008-07-31 IL IL193155A patent/IL193155A0/en unknown
- 2008-09-12 CR CR10286A patent/CR10286A/es not_active Application Discontinuation
- 2008-09-15 CU CU20080169A patent/CU23744B7/es active IP Right Grant
- 2008-09-15 EC EC2008008740A patent/ECSP088740A/es unknown
- 2008-09-16 GT GT200800182A patent/GT200800182A/es unknown
- 2008-10-14 ZA ZA200808754A patent/ZA200808754B/xx unknown
- 2008-10-14 NO NO20084301A patent/NO20084301L/no not_active Application Discontinuation
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2010
- 2010-07-30 US US12/847,277 patent/US20100298311A1/en not_active Abandoned
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2011
- 2011-10-19 CY CY20111100988T patent/CY1111954T1/el unknown
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