PL194589B1 - Sposób wytwarzania trombiny - Google Patents

Sposób wytwarzania trombiny

Info

Publication number
PL194589B1
PL194589B1 PL98340300A PL34030098A PL194589B1 PL 194589 B1 PL194589 B1 PL 194589B1 PL 98340300 A PL98340300 A PL 98340300A PL 34030098 A PL34030098 A PL 34030098A PL 194589 B1 PL194589 B1 PL 194589B1
Authority
PL
Poland
Prior art keywords
thrombin
solution
prothrombin
sodium
concentration
Prior art date
Application number
PL98340300A
Other languages
English (en)
Polish (pl)
Other versions
PL340300A1 (en
Inventor
Trung Bui-Khac
Original Assignee
Haemacure Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haemacure Corp filed Critical Haemacure Corp
Publication of PL340300A1 publication Critical patent/PL340300A1/xx
Publication of PL194589B1 publication Critical patent/PL194589B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0017—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10—Polypeptides; Proteins
    • A61L24/106—Fibrin; Fibrinogen
    • A61L2103/05—
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/908—Mechanical repair performed/surgical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Materials For Medical Uses (AREA)
PL98340300A 1997-10-30 1998-10-29 Sposób wytwarzania trombiny PL194589B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/960,660 US5981254A (en) 1997-10-30 1997-10-30 Process for producing thrombin from plasma
PCT/CA1998/001008 WO1999023111A1 (en) 1997-10-30 1998-10-29 Process for the production of highly viral safe components for forming fibrin glue from a pool of human plasma

Publications (2)

Publication Number Publication Date
PL340300A1 PL340300A1 (en) 2001-01-29
PL194589B1 true PL194589B1 (pl) 2007-06-29

Family

ID=25503448

Family Applications (1)

Application Number Title Priority Date Filing Date
PL98340300A PL194589B1 (pl) 1997-10-30 1998-10-29 Sposób wytwarzania trombiny

Country Status (16)

Country Link
US (1) US5981254A (OSRAM)
EP (1) EP1027371B1 (OSRAM)
JP (1) JP4278861B2 (OSRAM)
AT (1) ATE305011T1 (OSRAM)
AU (1) AU759145B2 (OSRAM)
CA (1) CA2307380A1 (OSRAM)
DE (1) DE69831684T2 (OSRAM)
DK (1) DK1027371T3 (OSRAM)
ES (1) ES2249843T3 (OSRAM)
IL (1) IL135812A (OSRAM)
IN (1) IN185759B (OSRAM)
NO (1) NO323299B1 (OSRAM)
NZ (1) NZ504246A (OSRAM)
PL (1) PL194589B1 (OSRAM)
RU (1) RU2236237C2 (OSRAM)
WO (1) WO1999023111A1 (OSRAM)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT407484B (de) * 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
JP5080713B2 (ja) * 1999-12-20 2012-11-21 田辺三菱製薬株式会社 多孔性膜処理によるウイルスの除去された血漿蛋白組成物の製造方法、ウイルスの除去された血漿蛋白組成物およびウイルス除去方法
AU779126B2 (en) * 1999-12-23 2005-01-06 Csl Limited Separation of fibrinogen from plasma proteases
WO2001048016A1 (en) * 1999-12-23 2001-07-05 Csl Limited Separation of fibrinogen from plasma proteases
JP2002114799A (ja) * 2000-08-01 2002-04-16 Nihon Pharmaceutical Co Ltd ウイルス除去方法
US7411006B2 (en) 2000-10-23 2008-08-12 Shanbrom Technologies, Llc Enhanced production of blood clotting factors and fibrin fabric
US7365173B2 (en) * 2002-02-04 2008-04-29 American National Red Cross Method for the production of pure virally inactivated butyrylcholinesterase
DE10211632A1 (de) * 2002-03-15 2003-10-09 Aventis Behring Gmbh Verfahren zur Abtrennung von Viren aus einer Proteinlösung durch Nanofiltration
US20070015230A1 (en) * 2002-04-15 2007-01-18 Hammond David J Identification and characterization of analytes from whole blood
US20060275753A1 (en) * 2002-04-15 2006-12-07 Hammond David J Recovery of analytes using combinatorial libraries
US20060275829A1 (en) * 2002-04-15 2006-12-07 Hammond David J Combinatorial library for proteomic investigations
CN100525829C (zh) * 2002-04-15 2009-08-12 美国国家红十字会 检测混合物中配体和靶标的方法
GB0216001D0 (en) 2002-07-10 2002-08-21 Nat Blood Authority Process and composition
DK1528930T3 (da) * 2002-07-23 2009-08-03 Bio & Bio Licensing Sa Thrombindannelsesdygtige og thrombinholdige farmaceutiske præparater af virksomt stof samt lægemidler
ES2214967B1 (es) * 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
ES2926359T3 (es) * 2003-12-01 2022-10-25 Novo Nordisk Healthcare Ag Filtración de virus de composiciones líquidas del Factor VII
WO2006009989A1 (en) * 2004-06-22 2006-01-26 Zymogenetics, Inc. Thrombin compositions
DE102004044429B4 (de) * 2004-09-14 2009-04-30 Biotest Ag Verfahren zur Herstellung einer Zusammensetzung enthaltend von Willebrand Faktor
ES2226587B1 (es) * 2004-10-22 2005-12-16 Probitas Pharma, S.A. Composicion de trombina estable.
US20060270015A1 (en) * 2005-05-26 2006-11-30 Dan Pawlak Thrombin purification
FR2887883B1 (fr) 2005-06-29 2007-08-31 Lab Francais Du Fractionnement Procede de separation des proteines fibrinogene, facteur xiii et colle biologique d'une fraction plasmatique solubilisee et de preparation de concentres lyophilises desdites proteines
US20120195953A1 (en) * 2007-09-19 2012-08-02 Kieu Hoang Fibrin sealant (FIBRINGLURAAS) consisting of a kit of lyophilized high concentrate fribinogen intentionally enriched and preserved with fibronolysis inhibitor A1AT
RU2369410C1 (ru) * 2008-05-06 2009-10-10 Александр Николаевич Данилин Способ очистки биологической жидкости организма (крови) от вирусной инфекции путем сорбции на магнитоуправляемых наночастицах и устройство для его осуществления
GB0814570D0 (en) * 2008-08-08 2008-09-17 Diagnostics For The Real World Isolation of nucleic acid
US9011846B2 (en) 2011-05-02 2015-04-21 Biomet Biologics, Llc Thrombin isolated from blood and blood fractions
AU2013322604B2 (en) * 2012-09-26 2018-01-18 Bone Therapeutics S.A. Formulations involving solvent/detergent-treated plasma (S/D plasma) and uses thereof
RU2583931C2 (ru) * 2014-06-11 2016-05-10 Федеральное государственное бюджетное учреждение Гематологический научный центр Министерства здравоохранения РФ Способ получения концентрата тромбина
US9932388B2 (en) 2014-11-13 2018-04-03 Hemarus Therapeutics Limited Chromatographic process for producing high purity fibrinogen and thrombin
JP6666757B2 (ja) * 2016-03-10 2020-03-18 日本メジフィジックス株式会社 ポリオキシエチレン系非イオン界面活性剤の定量方法及び放射性医薬品製剤の製造方法
PE20210457A1 (es) * 2018-02-19 2021-03-08 Bayer Healthcare Llc Membrana de filtro modificada y metodo
WO2020229521A1 (en) 2019-05-14 2020-11-19 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for inhibiting or reducing bacterial biofilms on a surface
CN113754757B (zh) * 2021-07-01 2024-06-14 华兰生物工程股份有限公司 一种人纤维蛋白原的制备方法
WO2023020914A1 (en) 2021-08-18 2023-02-23 Biotest Ag Dry heat treatment of plasma-derived factor viii
KR20230121373A (ko) * 2022-02-11 2023-08-18 주식회사 녹십자 인자 xiii의 정제방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3843126C3 (de) * 1988-12-22 1994-10-06 Octapharma Ag Verfahren zur Herstellung eines hochreinen Thrombinkonzentrates
RU2030183C1 (ru) * 1989-07-13 1995-03-10 Наталья Юрьевна Шатковская Состав для соединения биопластических материалов в отохирургии
RU2049470C1 (ru) * 1990-04-20 1995-12-10 Новокузнецкий институт усовершенствования врачей Способ получения альфа-макроглобулина
FR2679251B1 (fr) * 1991-07-18 1993-11-12 Nord Assoc Essor Transfusion San Procede de preparation d'un concentre de thrombine humaine destine a un usage therapeutique.
US5290918A (en) * 1993-02-23 1994-03-01 Haemacure Biotech Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by acidic precipitation
US5395923A (en) * 1993-02-23 1995-03-07 Haemacure-Biotech, Inc. Process for the obtention of a biological adhesive made of concentrated coagulation factors by "salting-out"
US5506127A (en) * 1994-09-21 1996-04-09 Proba; Zbigniew Therapeutic grade thrombin produced by chromatography
RU2062103C1 (ru) * 1994-09-29 1996-06-20 Московская медицинская академия им.И.М.Сеченова Способ получения концентрата фибриногена

Also Published As

Publication number Publication date
JP2001521941A (ja) 2001-11-13
CA2307380A1 (en) 1999-05-14
US5981254A (en) 1999-11-09
AU759145B2 (en) 2003-04-03
PL340300A1 (en) 2001-01-29
EP1027371B1 (en) 2005-09-21
ES2249843T3 (es) 2006-04-01
DE69831684D1 (de) 2006-02-02
NO323299B1 (no) 2007-03-05
RU2236237C2 (ru) 2004-09-20
DE69831684T2 (de) 2006-06-22
AU9731698A (en) 1999-05-24
IL135812A (en) 2007-09-20
WO1999023111A1 (en) 1999-05-14
JP4278861B2 (ja) 2009-06-17
IN185759B (OSRAM) 2001-04-21
IL135812A0 (en) 2001-05-20
NO20002293D0 (no) 2000-04-28
NO20002293L (no) 2000-06-30
NZ504246A (en) 2002-09-27
ATE305011T1 (de) 2005-10-15
DK1027371T3 (da) 2006-01-09
EP1027371A1 (en) 2000-08-16

Similar Documents

Publication Publication Date Title
PL194589B1 (pl) Sposób wytwarzania trombiny
US5099003A (en) Method of preparing a sterile plasma-protein solution containing fibrinogen and factor xiii
JP5719266B2 (ja) ウイルス不活性化熱処理へ供するための血漿タンパク質の寒冷沈降物を安定化する方法
US4490361A (en) Virus inactivating heat treatment of plasma fractions
KR960008653B1 (ko) γ-글로불린 주사용 액상 제제
AU2006202680B2 (en) Process for separating proteins fibrinogen, factor XIII and biological glue from a solubilized plasma fraction and for preparing lyophilised concentrates of said proteins
US4379085A (en) Heat stabilization of plasma proteins
EA003182B1 (ru) Универсальная плазма крови
JP5178518B2 (ja) 超高収率静注免疫グロブリン製剤
BRPI0312521B1 (pt) Método para a separação de fibrinogênio de plasminogênio
RU2112522C1 (ru) Состав для стабилизации плазмы крови, способ пастеризации плазмы и использование стабилизированной плазмы в терапии
FI81363C (fi) Foerfarande foer pastoerisering av preparat av blodkoaguleringsfaktorerna ii, vii, ix och x.
JP2879427B2 (ja) ウイルスおよびバクテリア汚染物の熱的不活性化中の生物学的および製薬的生成物の安定化
WO1998030230A1 (en) Protein-containing compositions and process for producing the same
JP4629831B2 (ja) ウィルスの不活化方法
RU2045902C1 (ru) Состав для стабилизации плазмы крови в ходе пастеризации и способ пастеризации плазмы крови
PT94859B (pt) Processo para a pasteurizacao de uma mistura de proteinas contendo fibrinogenio
de Lille llllllllllllllllllllllIlllllwglllllllllIllllllllllllllllllllllllllllllll
IE55182B1 (en) Heat treatment of plasma
HK1228805A1 (en) Plasma-supplemented formulation
CZ20001909A3 (cs) Použití tranexamové kyseliny pro výrobu prostředku lidského fibrinogenu a lidský fíbrinogenový prostředek

Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20101029