PL180968B1 - Sposób wytwarzania krystalicznej Lys Pro insuliny ludzkiej - Google Patents

Sposób wytwarzania krystalicznej Lys Pro insuliny ludzkiej

Info

Publication number
PL180968B1
PL180968B1 PL95309099A PL30909995A PL180968B1 PL 180968 B1 PL180968 B1 PL 180968B1 PL 95309099 A PL95309099 A PL 95309099A PL 30909995 A PL30909995 A PL 30909995A PL 180968 B1 PL180968 B1 PL 180968B1
Authority
PL
Poland
Prior art keywords
zinc
human insulin
insulin
crystals
solution
Prior art date
Application number
PL95309099A
Other languages
English (en)
Polish (pl)
Other versions
PL309099A1 (en
Inventor
Jeffrey C. Baker
Nancy D. Carter
Bruce H. Frank
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22990041&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL180968(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PL309099A1 publication Critical patent/PL309099A1/xx
Publication of PL180968B1 publication Critical patent/PL180968B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
PL95309099A 1994-06-16 1995-06-14 Sposób wytwarzania krystalicznej Lys Pro insuliny ludzkiej PL180968B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/260,647 US5504188A (en) 1994-06-16 1994-06-16 Preparation of stable zinc insulin analog crystals

Publications (2)

Publication Number Publication Date
PL309099A1 PL309099A1 (en) 1995-12-27
PL180968B1 true PL180968B1 (pl) 2001-05-31

Family

ID=22990041

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95309099A PL180968B1 (pl) 1994-06-16 1995-06-14 Sposób wytwarzania krystalicznej Lys Pro insuliny ludzkiej

Country Status (29)

Country Link
US (1) US5504188A (enFirst)
EP (1) EP0692489B1 (enFirst)
JP (1) JP3595607B2 (enFirst)
KR (1) KR100369951B1 (enFirst)
CN (1) CN1184234C (enFirst)
AT (1) ATE233278T1 (enFirst)
AU (1) AU697794B2 (enFirst)
BR (1) BR9502798A (enFirst)
CA (1) CA2151563C (enFirst)
CO (1) CO4410205A1 (enFirst)
CZ (1) CZ286066B6 (enFirst)
DE (1) DE69529708T2 (enFirst)
DK (1) DK0692489T3 (enFirst)
ES (1) ES2188637T3 (enFirst)
FI (1) FI952930A7 (enFirst)
HU (1) HUT73495A (enFirst)
IL (1) IL114152A (enFirst)
IN (1) IN178919B (enFirst)
MY (1) MY130551A (enFirst)
NO (1) NO952334L (enFirst)
NZ (1) NZ272358A (enFirst)
PE (1) PE21896A1 (enFirst)
PL (1) PL180968B1 (enFirst)
RO (1) RO113529B1 (enFirst)
RU (1) RU2156257C2 (enFirst)
SI (1) SI0692489T1 (enFirst)
TW (1) TW379228B (enFirst)
YU (1) YU39595A (enFirst)
ZA (1) ZA954942B (enFirst)

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CN104761632A (zh) * 2015-04-14 2015-07-08 珠海联邦制药股份有限公司 一种地特胰岛素结晶的制备方法及应用
CN106117345B (zh) * 2015-05-05 2020-11-24 宜昌东阳光长江药业股份有限公司 一种制备甘精胰岛素结晶的方法
CN104892749B (zh) * 2015-06-16 2019-02-05 珠海联邦制药股份有限公司 一种德谷胰岛素结晶的制备方法及应用
CN105753966A (zh) * 2016-05-05 2016-07-13 通化东宝药业股份有限公司 一种重组人胰岛素结晶的制备方法
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US5504188A (en) * 1994-06-16 1996-04-02 Eli Lilly And Company Preparation of stable zinc insulin analog crystals
US5597893A (en) * 1994-10-31 1997-01-28 Eli Lilly And Company Preparation of stable insulin analog crystals
AR002976A1 (es) * 1995-03-31 1998-05-27 Lilly Co Eli Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas

Also Published As

Publication number Publication date
CO4410205A1 (es) 1997-01-09
PL309099A1 (en) 1995-12-27
DE69529708T2 (de) 2003-10-16
CN1184234C (zh) 2005-01-12
EP0692489A1 (en) 1996-01-17
FI952930L (fi) 1995-12-17
DE69529708D1 (de) 2003-04-03
FI952930A7 (fi) 1995-12-17
NO952334D0 (no) 1995-06-13
HUT73495A (en) 1996-08-28
ZA954942B (en) 1996-12-17
CA2151563A1 (en) 1995-12-17
EP0692489B1 (en) 2003-02-26
CZ286066B6 (cs) 2000-01-12
DK0692489T3 (da) 2003-03-31
NO952334L (no) 1995-12-18
ES2188637T3 (es) 2003-07-01
YU39595A (sh) 1997-08-22
MY130551A (en) 2007-06-29
PE21896A1 (es) 1996-06-15
ATE233278T1 (de) 2003-03-15
CZ154195A3 (en) 1996-02-14
CA2151563C (en) 2007-08-07
IL114152A (en) 1999-12-31
AU697794B2 (en) 1998-10-15
RO113529B1 (ro) 1998-08-28
CN1128271A (zh) 1996-08-07
IL114152A0 (en) 1995-10-31
KR100369951B1 (ko) 2003-03-28
AU2168195A (en) 1996-01-04
BR9502798A (pt) 1996-06-04
US5504188A (en) 1996-04-02
JP3595607B2 (ja) 2004-12-02
IN178919B (enFirst) 1997-07-19
JPH08169899A (ja) 1996-07-02
NZ272358A (en) 1996-12-20
FI952930A0 (fi) 1995-06-14
SI0692489T1 (en) 2003-06-30
KR960000922A (ko) 1996-01-25
RU2156257C2 (ru) 2000-09-20
HU9501715D0 (en) 1995-08-28
TW379228B (en) 2000-01-11
RU95110107A (ru) 1997-05-10

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