PL1679074T3 - Środek terapeutyczny do leczenia chorób zapalnych rogówki i spojówki - Google Patents
Środek terapeutyczny do leczenia chorób zapalnych rogówki i spojówkiInfo
- Publication number
- PL1679074T3 PL1679074T3 PL04793171T PL04793171T PL1679074T3 PL 1679074 T3 PL1679074 T3 PL 1679074T3 PL 04793171 T PL04793171 T PL 04793171T PL 04793171 T PL04793171 T PL 04793171T PL 1679074 T3 PL1679074 T3 PL 1679074T3
- Authority
- PL
- Poland
- Prior art keywords
- therapeutic agent
- ylmethoxy
- benzimidazol
- thiazolidine
- dione
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003364864 | 2003-10-24 | ||
| EP04793171A EP1679074B1 (en) | 2003-10-24 | 2004-10-22 | Therapeutic agent for keratoconjunctive disorder |
| PCT/JP2004/016063 WO2005039574A1 (ja) | 2003-10-24 | 2004-10-22 | 角結膜障害の治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1679074T3 true PL1679074T3 (pl) | 2011-05-31 |
Family
ID=34510137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04793171T PL1679074T3 (pl) | 2003-10-24 | 2004-10-22 | Środek terapeutyczny do leczenia chorób zapalnych rogówki i spojówki |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7358255B2 (zh) |
| EP (1) | EP1679074B1 (zh) |
| JP (1) | JP4217832B2 (zh) |
| KR (1) | KR101154175B1 (zh) |
| CN (1) | CN1870997B (zh) |
| AT (1) | ATE490771T1 (zh) |
| CA (1) | CA2543452C (zh) |
| CY (1) | CY1111191T1 (zh) |
| DE (1) | DE602004030470D1 (zh) |
| DK (1) | DK1679074T3 (zh) |
| ES (1) | ES2357801T3 (zh) |
| PL (1) | PL1679074T3 (zh) |
| PT (1) | PT1679074E (zh) |
| SI (1) | SI1679074T1 (zh) |
| TW (1) | TWI343256B (zh) |
| WO (1) | WO2005039574A1 (zh) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1681054A1 (en) * | 2003-10-29 | 2006-07-19 | Santen Pharmaceutical Co., Ltd. | Therapeutic agent for keratoconjunctiva disorder |
| WO2006064825A1 (ja) * | 2004-12-14 | 2006-06-22 | Santen Pharmaceutical Co., Ltd. | ドライアイ治療剤 |
| JP5186217B2 (ja) | 2005-11-28 | 2013-04-17 | 千寿製薬株式会社 | Ｐｐａｒアゴニスト含有医薬 |
| RS55576B1 (sr) * | 2005-12-13 | 2017-05-31 | Incyte Holdings Corp | Heteroaril supstituisani pirolo[2,3-b]piridini i pirolo[2,3-b]pirimidini kao inhibitori janus kinaze |
| CN101801941B (zh) * | 2007-05-21 | 2012-12-12 | 千寿制药株式会社 | 含有ppar△激动剂的药物 |
| BRPI0814254B8 (pt) | 2007-06-13 | 2021-05-25 | Incyte Corp | sais do inibidor de janus quinase (r)-3-(4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)-3-ciclopentilpropanonitrila, seu método de preparação e composição que os compreende |
| EP2253325A4 (en) * | 2008-02-25 | 2012-07-04 | Santen Pharmaceutical Co Ltd | AGENT FOR IMPROVING THE CORNEAL EPITHELIAL BARRIER FUNCTION |
| CL2009001884A1 (es) * | 2008-10-02 | 2010-05-14 | Incyte Holdings Corp | Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco. |
| NZ596479A (en) * | 2009-05-22 | 2014-01-31 | Incyte Corp | N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| CN106967070A (zh) | 2009-05-22 | 2017-07-21 | 因塞特控股公司 | 作为jak抑制剂的化合物 |
| TW201113285A (en) * | 2009-09-01 | 2011-04-16 | Incyte Corp | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors |
| RS54823B1 (sr) | 2010-03-10 | 2016-10-31 | Incyte Holdings Corp | Derivati piperidin-4-il azetidina kao inhibitori jak1 |
| CA2799928C (en) | 2010-05-21 | 2020-03-31 | Incyte Corporation | Topical formulation for a jak inhibitor |
| US8933085B2 (en) | 2010-11-19 | 2015-01-13 | Incyte Corporation | Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
| US9034884B2 (en) | 2010-11-19 | 2015-05-19 | Incyte Corporation | Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors |
| JP5876146B2 (ja) | 2011-06-20 | 2016-03-02 | インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ | Ｊａｋ阻害剤としてのアゼチジニルフェニル、ピリジル、またはピラジニルカルボキサミド誘導体 |
| TW201313721A (zh) | 2011-08-18 | 2013-04-01 | Incyte Corp | 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物 |
| UA111854C2 (uk) | 2011-09-07 | 2016-06-24 | Інсайт Холдінгс Корпорейшн | Способи і проміжні сполуки для отримання інгібіторів jak |
| US9193733B2 (en) | 2012-05-18 | 2015-11-24 | Incyte Holdings Corporation | Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors |
| EA201590930A1 (ru) | 2012-11-15 | 2015-08-31 | Инсайт Корпорейшн | Лекарственные формы руксолитиниба с замедленным высвобождением |
| UA121532C2 (uk) | 2013-03-06 | 2020-06-10 | Інсайт Холдінгс Корпорейшн | Способи і проміжні сполуки при отриманні інгібітора jak |
| SG10201801069QA (en) | 2013-08-07 | 2018-03-28 | Incyte Corp | Sustained release dosage forms for a jak1 inhibitor |
| WO2015184305A1 (en) | 2014-05-30 | 2015-12-03 | Incyte Corporation | TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1 |
| US10596161B2 (en) | 2017-12-08 | 2020-03-24 | Incyte Corporation | Low dose combination therapy for treatment of myeloproliferative neoplasms |
| HRP20220510T1 (hr) | 2018-01-30 | 2022-05-27 | Incyte Corporation | Postupci za pripravu (1-(3-fluoro-2-(trifluorometil)izonikotinil) piperidin-4-ona) |
| IL277538B2 (en) | 2018-03-30 | 2024-09-01 | Incyte Corp | Use of JAK inhibitors to treat hidradenitis suppurativa |
| US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0264586B1 (en) | 1986-08-28 | 1991-04-03 | Sanwa Kagaku Kenkyusho Co., Ltd. | Hydantoin derivatives for treating complications of diabetes |
| JP3072227B2 (ja) * | 1994-08-01 | 2000-07-31 | 株式会社クボタ | 田植機の粉粒体供給装置 |
| JP3603129B2 (ja) | 1994-12-28 | 2004-12-22 | 株式会社三和化学研究所 | 糖尿病性角膜症の治療剤 |
| CZ293016B6 (cs) | 1995-06-01 | 2004-01-14 | Sankyo Company Limited | Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem |
| US6114526A (en) | 1996-07-01 | 2000-09-05 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| US6372750B2 (en) | 1996-07-01 | 2002-04-16 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases |
| US5885997A (en) | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| DE69723869T2 (de) | 1996-12-31 | 2004-04-22 | Dr. Reddy's Laboratories Ltd. | Heterozyklische verbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen die diese enthalten und ihre anwendung in der behandlung von diabetis und verwandten krankheiten |
| EP0909558A3 (en) * | 1997-08-29 | 1999-10-27 | Santen Pharmaceutical Co., Ltd. | Chroman derivative containing ophthalmic solution |
| JPH11130675A (ja) * | 1997-08-29 | 1999-05-18 | Santen Pharmaceut Co Ltd | クロマン誘導体含有点眼液 |
| JP2001039976A (ja) * | 1999-05-24 | 2001-02-13 | Sankyo Co Ltd | 縮合複素環化合物の塩酸塩 |
| TWI284533B (en) * | 1999-05-24 | 2007-08-01 | Sankyo Co | Pharmaceutical composition for treating hyperglycemia, impaired glucose tolerance, diabetes complications and for improving insulin resistant |
| TWI302149B (en) | 1999-09-22 | 2008-10-21 | Bristol Myers Squibb Co | Substituted acid derivatives useful as antiodiabetic and antiobesity agents and method |
| JP2002220336A (ja) | 2000-11-22 | 2002-08-09 | Sankyo Co Ltd | 縮合複素環化合物の塩酸塩を含有する糖尿病の予防薬、治療薬 |
| JP4090013B2 (ja) | 2000-12-26 | 2008-05-28 | 第一三共株式会社 | 利尿剤及びインスリン抵抗性改善剤を含有する医薬組成物 |
| EP1681054A1 (en) | 2003-10-29 | 2006-07-19 | Santen Pharmaceutical Co., Ltd. | Therapeutic agent for keratoconjunctiva disorder |
-
2004
- 2004-10-22 EP EP04793171A patent/EP1679074B1/en not_active Expired - Lifetime
- 2004-10-22 AT AT04793171T patent/ATE490771T1/de active
- 2004-10-22 JP JP2004307544A patent/JP4217832B2/ja not_active Expired - Fee Related
- 2004-10-22 TW TW093132101A patent/TWI343256B/zh not_active IP Right Cessation
- 2004-10-22 PT PT04793171T patent/PT1679074E/pt unknown
- 2004-10-22 DE DE602004030470T patent/DE602004030470D1/de not_active Expired - Lifetime
- 2004-10-22 PL PL04793171T patent/PL1679074T3/pl unknown
- 2004-10-22 CN CN2004800309819A patent/CN1870997B/zh not_active Expired - Fee Related
- 2004-10-22 KR KR1020067009936A patent/KR101154175B1/ko not_active IP Right Cessation
- 2004-10-22 CA CA2543452A patent/CA2543452C/en not_active Expired - Fee Related
- 2004-10-22 WO PCT/JP2004/016063 patent/WO2005039574A1/ja not_active Application Discontinuation
- 2004-10-22 SI SI200431607T patent/SI1679074T1/sl unknown
- 2004-10-22 DK DK04793171.2T patent/DK1679074T3/da active
- 2004-10-22 ES ES04793171T patent/ES2357801T3/es not_active Expired - Lifetime
- 2004-10-22 US US10/576,719 patent/US7358255B2/en not_active Expired - Fee Related
-
2011
- 2011-02-18 CY CY20111100206T patent/CY1111191T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2357801T3 (es) | 2011-04-29 |
| TWI343256B (en) | 2011-06-11 |
| WO2005039574A1 (ja) | 2005-05-06 |
| EP1679074A4 (en) | 2009-03-25 |
| CY1111191T1 (el) | 2015-06-11 |
| CA2543452A1 (en) | 2005-05-06 |
| CA2543452C (en) | 2012-03-13 |
| PT1679074E (pt) | 2011-03-03 |
| TW200518750A (en) | 2005-06-16 |
| EP1679074A1 (en) | 2006-07-12 |
| CN1870997A (zh) | 2006-11-29 |
| WO2005039574A8 (ja) | 2005-06-23 |
| KR101154175B1 (ko) | 2012-06-14 |
| US7358255B2 (en) | 2008-04-15 |
| DE602004030470D1 (de) | 2011-01-20 |
| KR20060100440A (ko) | 2006-09-20 |
| JP4217832B2 (ja) | 2009-02-04 |
| JP2005145961A (ja) | 2005-06-09 |
| EP1679074B1 (en) | 2010-12-08 |
| US20070060628A1 (en) | 2007-03-15 |
| CN1870997B (zh) | 2011-05-04 |
| ATE490771T1 (de) | 2010-12-15 |
| DK1679074T3 (da) | 2011-03-21 |
| SI1679074T1 (sl) | 2011-04-29 |
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