PL1638888T3 - Krystaliczna mezoporowata substancja krzemionkowa użyteczna do wiązania i kontrolowanego uwalniania aktywnych substancji leczniczych - Google Patents

Krystaliczna mezoporowata substancja krzemionkowa użyteczna do wiązania i kontrolowanego uwalniania aktywnych substancji leczniczych

Info

Publication number
PL1638888T3
PL1638888T3 PL04737677T PL04737677T PL1638888T3 PL 1638888 T3 PL1638888 T3 PL 1638888T3 PL 04737677 T PL04737677 T PL 04737677T PL 04737677 T PL04737677 T PL 04737677T PL 1638888 T3 PL1638888 T3 PL 1638888T3
Authority
PL
Poland
Prior art keywords
fixation
drugs
controlled release
mesoporous silica
silica material
Prior art date
Application number
PL04737677T
Other languages
English (en)
Inventor
Johan Adriaan Martens
Christine Eva Antonia Kirschhock
Sebastien Philippe Brigitte Kremer
Alexander Jan Maria Herman Eugeen Aerts
Den Mooter Guy Van
Humbeeck Jan Van
Original Assignee
K U Leuven Res & Development
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by K U Leuven Res & Development filed Critical K U Leuven Res & Development
Publication of PL1638888T3 publication Critical patent/PL1638888T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B37/00—Compounds having molecular sieve properties but not having base-exchange properties
    • C01B37/005—Silicates, i.e. so-called metallosilicalites or metallozeosilites
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B37/00—Compounds having molecular sieve properties but not having base-exchange properties
    • C01B37/02—Crystalline silica-polymorphs, e.g. silicalites dealuminated aluminosilicate zeolites
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/701—Integrated with dissimilar structures on a common substrate
    • Y10S977/712—Integrated with dissimilar structures on a common substrate formed from plural layers of nanosized material, e.g. stacked structures
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/831—Of specified ceramic or electrically insulating compositions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • General Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Geology (AREA)
  • Optics & Photonics (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Catalysts (AREA)
  • Steroid Compounds (AREA)
PL04737677T 2003-06-27 2004-06-28 Krystaliczna mezoporowata substancja krzemionkowa użyteczna do wiązania i kontrolowanego uwalniania aktywnych substancji leczniczych PL1638888T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0315012.5A GB0315012D0 (en) 2003-06-27 2003-06-27 Zeotiles
PCT/BE2004/000094 WO2005000740A2 (en) 2003-06-27 2004-06-28 Crystalline mesoporous oxide based materials useful for the fixation and controlled release of drugs
EP04737677A EP1638888B1 (en) 2003-06-27 2004-06-28 Crystalline mesoporous silica material useful for the fixation and controlled release of drugs

Publications (1)

Publication Number Publication Date
PL1638888T3 true PL1638888T3 (pl) 2009-10-30

Family

ID=27637462

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04737677T PL1638888T3 (pl) 2003-06-27 2004-06-28 Krystaliczna mezoporowata substancja krzemionkowa użyteczna do wiązania i kontrolowanego uwalniania aktywnych substancji leczniczych

Country Status (15)

Country Link
US (1) US7749521B2 (pl)
EP (3) EP1638888B1 (pl)
JP (2) JP4709140B2 (pl)
CN (1) CN100420628C (pl)
AT (1) ATE432242T1 (pl)
AU (1) AU2004251792B2 (pl)
CA (2) CA2529456A1 (pl)
DE (1) DE602004021256D1 (pl)
DK (1) DK1638888T3 (pl)
ES (2) ES2326651T3 (pl)
GB (1) GB0315012D0 (pl)
IL (2) IL172525A0 (pl)
PL (1) PL1638888T3 (pl)
WO (1) WO2005000740A2 (pl)
ZA (1) ZA200510399B (pl)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8273371B2 (en) * 2003-06-27 2012-09-25 Johan Adriaan Martens Crystalline mesoporous oxide based materials useful for the fixation and controlled release of drugs
WO2005082277A1 (en) * 2004-02-18 2005-09-09 Stanford University Drug delivery systems using mesoporous oxide films
US8097269B2 (en) 2004-02-18 2012-01-17 Celonova Biosciences, Inc. Bioactive material delivery systems comprising sol-gel compositions
US7589041B2 (en) * 2004-04-23 2009-09-15 Massachusetts Institute Of Technology Mesostructured zeolitic materials, and methods of making and using the same
EP1809349B1 (en) * 2004-07-05 2009-10-14 Ziscoat N.V. Biocompatible coating of medical devices comprising molecular sieves
GB0420016D0 (en) 2004-09-09 2004-10-13 Leuven K U Res & Dev Controlled release oral delivery system
US7776682B1 (en) * 2005-04-20 2010-08-17 Spansion Llc Ordered porosity to direct memory element formation
WO2007133758A1 (en) * 2006-05-15 2007-11-22 Physical Pharmaceutica, Llc Composition and improved method for preparation of small particles
KR101462693B1 (ko) * 2006-08-16 2014-11-17 노파르티스 아게 고도 결정질 치료용 화합물의 고체 분산체 제조 방법
JP5509595B2 (ja) * 2006-09-08 2014-06-04 日立化成株式会社 カーボンナノチューブの製造方法
EP2089040B1 (en) * 2006-12-05 2012-01-04 Unilever PLC Oral care product
CN101209970B (zh) * 2006-12-25 2011-06-22 上海海隼化工科技有限公司 二乙二醇单乙酯和二乙二醇双乙酯的制备方法
JP5158670B2 (ja) * 2007-02-14 2013-03-06 独立行政法人産業技術総合研究所 円筒のアルミナ細孔内における界面活性剤を鋳型としたメソポーラスシリカの構造
EP2170294A1 (en) * 2007-06-25 2010-04-07 Pharmathen S.A. Improved pharmaceutical formulation containing an hmg-coa reductase inhibitor and method for the preparation thereof
US8258137B2 (en) * 2008-01-29 2012-09-04 Katholieke Universiteit Leuven Process for release of biologically active species from mesoporous oxide systems
CN101939258B (zh) * 2008-02-11 2014-05-14 纳诺洛吉卡股份公司 中孔材料的制造方法、这样生产的材料以及中孔材料的用途
US9114125B2 (en) 2008-04-11 2015-08-25 Celonova Biosciences, Inc. Drug eluting expandable devices
TWI410279B (zh) * 2008-08-27 2013-10-01 China Steel Corp A Synthetic Method of Double - pore Molecular Sieve in Cave
KR20110110097A (ko) * 2008-10-28 2011-10-06 에이전시 포 사이언스, 테크놀로지 앤드 리서치 수난용성 성분을 위한 메조포러스 물질 부형제
WO2011110662A1 (en) * 2010-03-11 2011-09-15 Danmarks Tekniske Universitet Supported biologically active compounds
CN102451158A (zh) * 2010-10-28 2012-05-16 沈阳药科大学 尼莫地平-SiO2纳米球及其制备和应用
AU2012240093B2 (en) * 2011-04-08 2015-06-11 W. R. Grace & Co.-Conn. Mesoporous framework-modified zeolites
US10577250B2 (en) 2011-05-13 2020-03-03 Merck Patent Gmbh Process for producing of inorganic particulate material
CA2836782A1 (en) * 2011-05-13 2012-11-22 Mario Maio Process for producing inorganic particulate material
CN102676494B (zh) * 2012-05-03 2013-10-30 天津大学 核壳结构固定化酶颗粒及其制备方法
US10732115B2 (en) 2012-06-22 2020-08-04 Cornell University Mesoporous oxide nanoparticles and methods of making and using same
ES2821528T3 (es) * 2012-11-14 2021-04-26 Grace W R & Co Composiciones que contienen un material biológicamente activo y un óxido inorgánico no ordenado
KR20160089504A (ko) 2013-11-26 2016-07-27 메르크 파텐트 게엠베하 무기 미립자 재료의 제조 방법
WO2016145335A1 (en) * 2015-03-11 2016-09-15 Stc.Unm Generation of mesoporous materials using multiphase surfactant systems
WO2017120504A1 (en) 2016-01-08 2017-07-13 Durfee Paul N Osteotropic nanoparticles for prevention or treatment of bone metastases
WO2018160865A1 (en) 2017-03-01 2018-09-07 Charles Jeffrey Brinker Active targeting of cells by monosized protocells
EP3636282A4 (en) * 2017-05-19 2020-11-04 Tokuyama Corporation CARRIERS OF A PHARMACEUTICAL INGREDIENT AND METHOD OF MANUFACTURING THEREOF
KR102140687B1 (ko) 2017-11-30 2020-08-05 한국생산기술연구원 다양한 약물의 방출 제어가 가능한 다공성 나노입자로 코팅된 임플란트
WO2020127281A1 (en) 2018-12-20 2020-06-25 Merck Patent Gmbh A release system comprising a bioactive agent and a particulate material
CN111904946B (zh) * 2019-05-10 2021-09-17 西安电子科技大学 一种基于仿生狂犬病毒的纳米诊疗制剂及其制备方法与应用
KR102368479B1 (ko) * 2020-03-03 2022-02-28 서울대학교산학협력단 나노입자 구조체 및 그 형성 방법
US20230263728A1 (en) * 2022-02-22 2023-08-24 DGP Technology Limited Biologically active additive based on mesoporous silicon dioxide and on micellar solutions of active substrates and method for preparing same

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3639637A (en) 1968-04-23 1972-02-01 Richardson Merrell Inc Water dispersible diethylstilbestrol compositions
US4235892A (en) 1979-02-05 1980-11-25 Schering Corporation, Patent Dept. 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor
GB8913889D0 (en) 1989-06-16 1989-08-02 May & Baker Ltd New compositions of matter
US5102643A (en) 1990-01-25 1992-04-07 Mobil Oil Corp. Composition of synthetic porous crystalline material, its synthesis
US5057296A (en) * 1990-12-10 1991-10-15 Mobil Oil Corp. Method for synthesizing mesoporous crystalline material
EP0617612B1 (en) 1991-12-18 1997-09-10 Warner-Lambert Company A process for the preparation of a solid dispersion
JPH06285358A (ja) * 1993-04-06 1994-10-11 Kao Corp 徐放性金属酸化物中空微粒子及びその製造方法
US5646131A (en) 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
DE19624862A1 (de) * 1996-06-21 1998-01-02 Basf Ag Mesoporöse Oxidformkörper
HN1998000115A (es) 1997-08-21 1999-06-02 Warner Lambert Co Formas de dosificación farmacéuticas sólidas
AU9062998A (en) 1997-09-11 1999-03-29 Nycomed Danmark A/S Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (nsaids)
KR100624648B1 (ko) 1997-12-09 2006-09-19 에스비에이 머티어리얼스 인코포레이티드 메소구조의 무기 산화물을 제조하기 위한 블록 중합체 공정
AU1684101A (en) 1999-11-23 2001-06-04 Universite Laval Mesoporous zeolitic material with microporous crystalline mesopore walls
AU2001280918A1 (en) 2000-07-31 2002-02-13 Drexel University Direct encapsulation of biomacromolecules in surfactant templated mesoporous andnanoporous materials
WO2002010218A1 (en) * 2000-07-31 2002-02-07 Drexel University Direct encapsulation of biomacromolecules in surfactant templated mesoporous and nanoporous materials
JP2005504505A (ja) * 2001-02-21 2005-02-17 バッテル　メモリアル　インスティテュート 多孔質担体中のタンパク質
US7846684B2 (en) 2001-02-21 2010-12-07 Battelle Memorial Institute Enzyme system comprising an enzyme bonded in a porous matrix
US6630170B2 (en) 2001-04-26 2003-10-07 Board Of Regents The University Of Texas System Mesoporous compositions and method of preparation
CN1142094C (zh) * 2001-08-24 2004-03-17 复旦大学 一种新型立方结构介孔二氧化硅分子筛的合成方法
JP4099811B2 (ja) * 2002-03-18 2008-06-11 独立行政法人産業技術総合研究所 定形多孔質シリカ乃至シリカ金属複合体粒子及びその製造方法

Also Published As

Publication number Publication date
DE602004021256D1 (de) 2009-07-09
CN1812932A (zh) 2006-08-02
EP1852393A1 (en) 2007-11-07
JP4709140B2 (ja) 2011-06-22
ES2414959T3 (es) 2013-07-23
IL213176A0 (en) 2011-07-31
JP2007523817A (ja) 2007-08-23
GB0315012D0 (en) 2003-07-30
DK1638888T3 (da) 2009-08-10
US20060134219A1 (en) 2006-06-22
EP2336086A1 (en) 2011-06-22
EP1852393B1 (en) 2013-04-10
CA2529456A1 (en) 2005-01-06
US7749521B2 (en) 2010-07-06
JP2011063601A (ja) 2011-03-31
ES2326651T3 (es) 2009-10-16
CN100420628C (zh) 2008-09-24
IL213176A (en) 2016-11-30
EP1638888B1 (en) 2009-05-27
EP1638888A2 (en) 2006-03-29
AU2004251792A1 (en) 2005-01-06
CA2723328C (en) 2013-02-05
CA2723328A1 (en) 2005-01-06
IL172525A0 (en) 2006-04-10
WO2005000740A2 (en) 2005-01-06
JP5296761B2 (ja) 2013-09-25
WO2005000740A3 (en) 2005-02-17
AU2004251792B2 (en) 2009-08-13
ZA200510399B (en) 2006-12-27
ATE432242T1 (de) 2009-06-15

Similar Documents

Publication Publication Date Title
PL1638888T3 (pl) Krystaliczna mezoporowata substancja krzemionkowa użyteczna do wiązania i kontrolowanego uwalniania aktywnych substancji leczniczych
DE60022441D1 (de) Vorrichtung zur automatischen regelung der medikamentenabgabe
WO2002070029A3 (en) Porous beta-tricalcium phosphate granules and methods for producing same
DE60325715D1 (de) Methoden und darreichungsformen zur kontrollierten freisetzung von oxykodon
AU2003212437A8 (en) Methods, devices, and articles for controlling the release of volatile materials
ATE241264T1 (de) Stützvorrichtung zur abgabe von flüchtigen stoffen
WO2005117919A3 (en) Delayed-setting calcium phosphate pastes
ATE324053T1 (de) Verfahren und verbindungen zur kontrolle des körpergewichts
HK1097828A1 (en) 42-0-alkoxyalkyl rapamycin derivatives and compositions comprising same
HK1045693A1 (en) Bicyclic compounds composition and method for stabilizing the same.
WO2002015881A3 (en) Use of a porous carrier
WO2002040000A3 (en) Use of cci-779 as an antineoplastic agent
DE50203336D1 (de) Vorrichtung zur steuerung von chirurgischen instrumenten
ATE103820T1 (de) Absorbierbare beschichtung und mischung.
SE0102389D0 (sv) Förfarande vid implantat samt sådant implantat
DE60115800D1 (de) Steuerungsverfahren zur Beschleunigung und zur Verzögerung
ATE226078T1 (de) Pharmazeutische zusammensetzung enthaltend ein osteogenese foerderndes mittel und ein polyethylen-glycol
DE69835381D1 (de) Automatische Schneidvorrichtung, Verfahren zur Steuerung derselben und zugehöriges Druckgerät
DE60125990D1 (de) Aufzugsvorrichtung und zugehörige vorrichtung zur begrenzung der kabinenbewegung
WO2001037813A3 (de) Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen
IT1317070B1 (it) Pilastro di guarigione per immobilizzazione intrachirurgica diimpianti dentali per carico immediato.
DK1339417T3 (da) Præparat til behandling af åbne, flade sår
AU2003295163A1 (en) Composition for the treatment of hiv or aids
AU2002231897A1 (en) Device for cutting grafts
ATE354320T1 (de) Orbitalimplantat