WO2001037813A3 - Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen - Google Patents

Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen Download PDF

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Publication number
WO2001037813A3
WO2001037813A3 PCT/EP2000/010934 EP0010934W WO0137813A3 WO 2001037813 A3 WO2001037813 A3 WO 2001037813A3 EP 0010934 W EP0010934 W EP 0010934W WO 0137813 A3 WO0137813 A3 WO 0137813A3
Authority
WO
WIPO (PCT)
Prior art keywords
controlled
active substances
pulsed release
preparation
multilayer preparation
Prior art date
Application number
PCT/EP2000/010934
Other languages
English (en)
French (fr)
Other versions
WO2001037813A2 (de
Inventor
Falkenhausen Christian Von
Markus Krumme
Original Assignee
Lohmann Therapie Syst Lts
Falkenhausen Christian Von
Markus Krumme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts, Falkenhausen Christian Von, Markus Krumme filed Critical Lohmann Therapie Syst Lts
Priority to IL14983600A priority Critical patent/IL149836A0/xx
Priority to JP2001539428A priority patent/JP2003514846A/ja
Priority to AU30034/01A priority patent/AU782141B2/en
Priority to EP00990596A priority patent/EP1231899A2/de
Priority to CA002391962A priority patent/CA2391962A1/en
Publication of WO2001037813A2 publication Critical patent/WO2001037813A2/de
Publication of WO2001037813A3 publication Critical patent/WO2001037813A3/de
Priority to IL149836A priority patent/IL149836A/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Addiction (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Laminated Bodies (AREA)

Abstract

Eine mehrschichtige Zubereitung zur gesteuerten, pulsartigen Abgabe von Wirkstoffen ist dadurch gekennzeichnet, daß die Zubereitung mindestens vier Schichten aufweist, von denen mindestens zwei nicht benachbarte Schichten einen beliebigen Wirkstoff A enthalten.
PCT/EP2000/010934 1999-11-24 2000-11-06 Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen WO2001037813A2 (de)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IL14983600A IL149836A0 (en) 1999-11-24 2000-11-06 Multilayer preparation for a controlled, pulsed release of active substances
JP2001539428A JP2003514846A (ja) 1999-11-24 2000-11-06 活性物質の制御された脈状放出のための多層製剤
AU30034/01A AU782141B2 (en) 1999-11-24 2000-11-06 Multilayer preparation for a controlled, pulsed release of active substances
EP00990596A EP1231899A2 (de) 1999-11-24 2000-11-06 Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen
CA002391962A CA2391962A1 (en) 1999-11-24 2000-11-06 Multilayer preparation for a controlled, pulsed release of active substances
IL149836A IL149836A (en) 1999-11-24 2002-05-23 A multi-layered preparation for pulsed controlled release of active ingredients

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19956486.8 1999-11-24
DE19956486A DE19956486A1 (de) 1999-11-24 1999-11-24 Mehrschichtige Zubereitung zur gesteuerten, pulsartigen Abgabe von Wirkstoffen

Publications (2)

Publication Number Publication Date
WO2001037813A2 WO2001037813A2 (de) 2001-05-31
WO2001037813A3 true WO2001037813A3 (de) 2001-12-27

Family

ID=7930143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/010934 WO2001037813A2 (de) 1999-11-24 2000-11-06 Mehrschichtige zubereitung zur gesteuerten, pulsartigen abgabe von wirkstoffen

Country Status (10)

Country Link
EP (1) EP1231899A2 (de)
JP (1) JP2003514846A (de)
KR (1) KR100690518B1 (de)
CN (1) CN1399544A (de)
AR (1) AR026590A1 (de)
AU (1) AU782141B2 (de)
CA (1) CA2391962A1 (de)
DE (1) DE19956486A1 (de)
IL (2) IL149836A0 (de)
WO (1) WO2001037813A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393192B2 (en) 2002-07-29 2016-07-19 Alza Corporation Methods and dosage forms for controlled delivery of paliperidone and risperidone

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR839001A0 (en) * 2001-10-19 2001-11-15 Eli Lilly And Company Dosage form, device and methods of treatment
ES2663873T3 (es) * 2001-10-29 2018-04-17 Massachusetts Institute Of Technology Forma farmacéutica con perfil de liberación de orden cero fabricada por impresión tridimensional
DE10353186A1 (de) * 2003-11-13 2005-06-16 Röhm GmbH & Co. KG Mehrschichtige Arzneiform, enthaltend eine in Bezug auf die Wirkstoffabgabe modulatorisch wirkende Substanz
US7670624B2 (en) * 2004-01-29 2010-03-02 Astella Pharma Inc. Gastrointestinal-specific multiple drug release system
KR20070119658A (ko) * 2005-03-29 2007-12-20 에보니크 룀 게엠베하 활성 성분 방출에 대한 조절 효과를 가지는 물질을포함하는 펠렛을 포함하는 다중 미립자 제약 형태
CN101111230B (zh) * 2005-03-29 2010-05-19 赢创罗姆有限责任公司 包含对活性成分具有调节释放作用的小丸的多颗粒药用形式
GB0707489D0 (en) * 2007-04-18 2007-05-23 Renaissance Pharma Compounds
CN102764243B (zh) * 2011-05-06 2014-10-29 上海医药工业研究院 一种阿司匹林脉冲释放微丸和其制剂及其制备方法
EP3302442A4 (de) * 2015-06-03 2019-02-06 Triastek, Inc. Darreichungsform und verwendung davon
SG11201803496RA (en) * 2015-10-26 2018-05-30 Agency Science Tech & Res Core-shell composite material
JP7040418B2 (ja) * 2018-11-21 2022-03-23 株式会社村田製作所 錠剤
JP7502741B2 (ja) 2019-09-26 2024-06-19 スピンセンシングファクトリー株式会社 磁気マーカーおよび磁気マーカー検出システム

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB793808A (en) * 1954-07-22 1958-04-23 Frank Mario Bardani Sustained action pill
US2991226A (en) * 1958-02-03 1961-07-04 Frosst & Co Charles E Long-acting wax-like talc pillage of penicillin
EP0230564A1 (de) * 1985-12-02 1987-08-05 Bando Chemical Industries, Ltd. Bodenbelag aus Kautschuk
EP0411590A2 (de) * 1989-08-02 1991-02-06 ARNOLD, John David Verfahren und Mittel zur Verminderung des Herzinfarktrisikos
US5236713A (en) * 1987-10-21 1993-08-17 Teikoku Seiyaku Kabushiki Kaisha Preparation for intermittently releasing active agent applicable to oral cavity
EP0807433A1 (de) * 1994-12-27 1997-11-19 Kanebo Ltd. Zubereitung mit verzögerter freisetzung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011692A (en) * 1985-12-28 1991-04-30 Sumitomo Pharmaceuticals Company, Limited Sustained pulsewise release pharmaceutical preparation
JPH09504810A (ja) * 1993-08-19 1997-05-13 シグナス，インコーポレイテッド 水溶性感圧粘膜接着剤

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB793808A (en) * 1954-07-22 1958-04-23 Frank Mario Bardani Sustained action pill
US2991226A (en) * 1958-02-03 1961-07-04 Frosst & Co Charles E Long-acting wax-like talc pillage of penicillin
EP0230564A1 (de) * 1985-12-02 1987-08-05 Bando Chemical Industries, Ltd. Bodenbelag aus Kautschuk
US5236713A (en) * 1987-10-21 1993-08-17 Teikoku Seiyaku Kabushiki Kaisha Preparation for intermittently releasing active agent applicable to oral cavity
EP0411590A2 (de) * 1989-08-02 1991-02-06 ARNOLD, John David Verfahren und Mittel zur Verminderung des Herzinfarktrisikos
EP0807433A1 (de) * 1994-12-27 1997-11-19 Kanebo Ltd. Zubereitung mit verzögerter freisetzung

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9393192B2 (en) 2002-07-29 2016-07-19 Alza Corporation Methods and dosage forms for controlled delivery of paliperidone and risperidone

Also Published As

Publication number Publication date
AU3003401A (en) 2001-06-04
CN1399544A (zh) 2003-02-26
KR20020058027A (ko) 2002-07-12
AU782141B2 (en) 2005-07-07
CA2391962A1 (en) 2001-05-31
IL149836A0 (en) 2002-11-10
IL149836A (en) 2008-08-07
AR026590A1 (es) 2003-02-19
WO2001037813A2 (de) 2001-05-31
JP2003514846A (ja) 2003-04-22
EP1231899A2 (de) 2002-08-21
KR100690518B1 (ko) 2007-03-09
DE19956486A1 (de) 2001-06-21

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