PL1603919T3 - Pochodne 7-iminowe kamptotecyny o aktywności przeciwrakowej - Google Patents

Pochodne 7-iminowe kamptotecyny o aktywności przeciwrakowej

Info

Publication number
PL1603919T3
PL1603919T3 PL04719039T PL04719039T PL1603919T3 PL 1603919 T3 PL1603919 T3 PL 1603919T3 PL 04719039 T PL04719039 T PL 04719039T PL 04719039 T PL04719039 T PL 04719039T PL 1603919 T3 PL1603919 T3 PL 1603919T3
Authority
PL
Poland
Prior art keywords
camptothecin
antitumor activity
imino derivatives
imino
derivatives
Prior art date
Application number
PL04719039T
Other languages
English (en)
Polish (pl)
Inventor
Sabrina Dallavalle
Sergio Penco
C Pisano
F Zunino
Original Assignee
Sigma Tau Ind Farmaceuti
Istituto Naz Per Lo Studio E La Cura Dei Tumori
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti, Istituto Naz Per Lo Studio E La Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti
Publication of PL1603919T3 publication Critical patent/PL1603919T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06Antimalarials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL04719039T 2003-03-17 2004-03-10 Pochodne 7-iminowe kamptotecyny o aktywności przeciwrakowej PL1603919T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,587 US7105492B2 (en) 1999-03-09 2003-03-17 Camptothecin derivatives having antitumor activity
EP04719039A EP1603919B1 (en) 2003-03-17 2004-03-10 7-imino derivatives of camptothecin having antitumor activity
PCT/IT2004/000118 WO2004083214A1 (en) 2003-03-17 2004-03-10 7-imino derivatives of camptothecin having antitumor activity

Publications (1)

Publication Number Publication Date
PL1603919T3 true PL1603919T3 (pl) 2009-06-30

Family

ID=33029646

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04719039T PL1603919T3 (pl) 2003-03-17 2004-03-10 Pochodne 7-iminowe kamptotecyny o aktywności przeciwrakowej

Country Status (19)

Country Link
US (2) US7105492B2 (https=)
EP (1) EP1603919B1 (https=)
JP (1) JP4791355B2 (https=)
KR (1) KR101174112B1 (https=)
CN (1) CN100372855C (https=)
AR (1) AR043620A1 (https=)
AT (1) ATE417851T1 (https=)
AU (1) AU2004222044B2 (https=)
BR (1) BRPI0408380A (https=)
CA (1) CA2517450C (https=)
CY (1) CY1108890T1 (https=)
DE (1) DE602004018468D1 (https=)
DK (1) DK1603919T3 (https=)
ES (1) ES2319293T3 (https=)
PL (1) PL1603919T3 (https=)
PT (1) PT1603919E (https=)
SI (1) SI1603919T1 (https=)
TW (1) TWI341840B (https=)
WO (1) WO2004083214A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105492B2 (en) * 1999-03-09 2006-09-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
ITRM20030344A1 (it) * 2003-07-14 2005-01-15 Ist Naz Stud Cura Dei Tumori 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
ITRM20040288A1 (it) * 2004-06-11 2004-09-11 Sigma Tau Ind Farmaceuti Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero.
CN101080227B (zh) * 2004-12-15 2011-08-31 诺瓦提斯公司 用于治疗癌症的治疗剂的组合
US7291936B1 (en) * 2006-05-03 2007-11-06 Robson John H Submersible electrical power generating plant
CN102731516B (zh) * 2011-04-07 2014-07-02 宁波天衡药业股份有限公司 一类具有抗肿瘤活性的喜树碱衍生物
WO2022140504A1 (en) * 2020-12-23 2022-06-30 Shanghai Ruotuo Biosciences Co., Ltd. Antibody-drug conjugates, pharmaceutical compositions, and therapeutic applications

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399276A (en) 1981-01-09 1983-08-16 Kabushiki Kaisha Yakult Honsha 7-Substituted camptothecin derivatives
JPS58154582A (ja) 1982-03-10 1983-09-14 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体およびその製造法
ATE247471T1 (de) 1991-11-15 2003-09-15 Smithkline Beecham Corp Cisplatin und topotecan enthaltende zusammensetzung als antitumor.
US5614529A (en) 1994-09-22 1997-03-25 Research Triangle Institute Inhibition of plasmodia parasites by camptothecin compounds
US5972955A (en) 1995-06-06 1999-10-26 Dr. Reddy's Research Foundation Water soluble C-ring analogues of 20(S)-camptothecin
IT1282673B1 (it) 1996-02-23 1998-03-31 Ist Naz Stud Cura Dei Tumori Derivati della camptotecina e loro uso come agenti antitumorali
KR100516593B1 (ko) 1996-08-19 2005-09-22 바이오누머릭 파마슈티칼스, 인코포레이티드 고 친유성 캠프토테신 유도체
US7105492B2 (en) * 1999-03-09 2006-09-12 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Camptothecin derivatives having antitumor activity
EP1044977B1 (en) 1999-03-09 2002-05-02 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Camptothecin derivatives having antitumor activity

Also Published As

Publication number Publication date
AR043620A1 (es) 2005-08-03
KR101174112B1 (ko) 2012-08-16
AU2004222044A1 (en) 2004-09-30
WO2004083214A1 (en) 2004-09-30
HK1089160A1 (zh) 2006-11-24
CN100372855C (zh) 2008-03-05
JP4791355B2 (ja) 2011-10-12
DK1603919T3 (da) 2009-03-09
US7105492B2 (en) 2006-09-12
US7351714B2 (en) 2008-04-01
US20060167033A1 (en) 2006-07-27
EP1603919A1 (en) 2005-12-14
PT1603919E (pt) 2009-02-16
CY1108890T1 (el) 2014-07-02
CA2517450C (en) 2011-06-14
DE602004018468D1 (de) 2009-01-29
AU2004222044B2 (en) 2010-02-25
CA2517450A1 (en) 2004-09-30
TW200504076A (en) 2005-02-01
US20040018988A1 (en) 2004-01-29
TWI341840B (en) 2011-05-11
JP2006520807A (ja) 2006-09-14
CN1761668A (zh) 2006-04-19
SI1603919T1 (sl) 2009-04-30
ATE417851T1 (de) 2009-01-15
BRPI0408380A (pt) 2006-03-21
KR20050107756A (ko) 2005-11-15
ES2319293T3 (es) 2009-05-06
EP1603919B1 (en) 2008-12-17

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