DE602004018468D1 - 7-iminoderivate von camptothecin mit antitumorwirkung - Google Patents
7-iminoderivate von camptothecin mit antitumorwirkungInfo
- Publication number
- DE602004018468D1 DE602004018468D1 DE602004018468T DE602004018468T DE602004018468D1 DE 602004018468 D1 DE602004018468 D1 DE 602004018468D1 DE 602004018468 T DE602004018468 T DE 602004018468T DE 602004018468 T DE602004018468 T DE 602004018468T DE 602004018468 D1 DE602004018468 D1 DE 602004018468D1
- Authority
- DE
- Germany
- Prior art keywords
- iminoderivate
- camptothecin
- antitumor effect
- antitumor
- effect
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/388,587 US7105492B2 (en) | 1999-03-09 | 2003-03-17 | Camptothecin derivatives having antitumor activity |
| PCT/IT2004/000118 WO2004083214A1 (en) | 2003-03-17 | 2004-03-10 | 7-imino derivatives of camptothecin having antitumor activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE602004018468D1 true DE602004018468D1 (de) | 2009-01-29 |
Family
ID=33029646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE602004018468T Expired - Lifetime DE602004018468D1 (de) | 2003-03-17 | 2004-03-10 | 7-iminoderivate von camptothecin mit antitumorwirkung |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7105492B2 (https=) |
| EP (1) | EP1603919B1 (https=) |
| JP (1) | JP4791355B2 (https=) |
| KR (1) | KR101174112B1 (https=) |
| CN (1) | CN100372855C (https=) |
| AR (1) | AR043620A1 (https=) |
| AT (1) | ATE417851T1 (https=) |
| AU (1) | AU2004222044B2 (https=) |
| BR (1) | BRPI0408380A (https=) |
| CA (1) | CA2517450C (https=) |
| CY (1) | CY1108890T1 (https=) |
| DE (1) | DE602004018468D1 (https=) |
| DK (1) | DK1603919T3 (https=) |
| ES (1) | ES2319293T3 (https=) |
| PL (1) | PL1603919T3 (https=) |
| PT (1) | PT1603919E (https=) |
| SI (1) | SI1603919T1 (https=) |
| TW (1) | TWI341840B (https=) |
| WO (1) | WO2004083214A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105492B2 (en) * | 1999-03-09 | 2006-09-12 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
| ITRM20030344A1 (it) * | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
| ITRM20040288A1 (it) * | 2004-06-11 | 2004-09-11 | Sigma Tau Ind Farmaceuti | Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero. |
| CN101080227B (zh) * | 2004-12-15 | 2011-08-31 | 诺瓦提斯公司 | 用于治疗癌症的治疗剂的组合 |
| US7291936B1 (en) * | 2006-05-03 | 2007-11-06 | Robson John H | Submersible electrical power generating plant |
| CN102731516B (zh) * | 2011-04-07 | 2014-07-02 | 宁波天衡药业股份有限公司 | 一类具有抗肿瘤活性的喜树碱衍生物 |
| WO2022140504A1 (en) * | 2020-12-23 | 2022-06-30 | Shanghai Ruotuo Biosciences Co., Ltd. | Antibody-drug conjugates, pharmaceutical compositions, and therapeutic applications |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399276A (en) | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| JPS58154582A (ja) | 1982-03-10 | 1983-09-14 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体およびその製造法 |
| ATE247471T1 (de) | 1991-11-15 | 2003-09-15 | Smithkline Beecham Corp | Cisplatin und topotecan enthaltende zusammensetzung als antitumor. |
| US5614529A (en) | 1994-09-22 | 1997-03-25 | Research Triangle Institute | Inhibition of plasmodia parasites by camptothecin compounds |
| US5972955A (en) | 1995-06-06 | 1999-10-26 | Dr. Reddy's Research Foundation | Water soluble C-ring analogues of 20(S)-camptothecin |
| IT1282673B1 (it) | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | Derivati della camptotecina e loro uso come agenti antitumorali |
| KR100516593B1 (ko) | 1996-08-19 | 2005-09-22 | 바이오누머릭 파마슈티칼스, 인코포레이티드 | 고 친유성 캠프토테신 유도체 |
| US7105492B2 (en) * | 1999-03-09 | 2006-09-12 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
| EP1044977B1 (en) | 1999-03-09 | 2002-05-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. | Camptothecin derivatives having antitumor activity |
-
2003
- 2003-03-17 US US10/388,587 patent/US7105492B2/en not_active Expired - Fee Related
-
2004
- 2004-03-04 TW TW093105744A patent/TWI341840B/zh not_active IP Right Cessation
- 2004-03-10 DE DE602004018468T patent/DE602004018468D1/de not_active Expired - Lifetime
- 2004-03-10 PT PT04719039T patent/PT1603919E/pt unknown
- 2004-03-10 AU AU2004222044A patent/AU2004222044B2/en not_active Ceased
- 2004-03-10 JP JP2006507637A patent/JP4791355B2/ja not_active Expired - Fee Related
- 2004-03-10 ES ES04719039T patent/ES2319293T3/es not_active Expired - Lifetime
- 2004-03-10 CA CA2517450A patent/CA2517450C/en not_active Expired - Fee Related
- 2004-03-10 US US10/546,211 patent/US7351714B2/en not_active Expired - Fee Related
- 2004-03-10 BR BRPI0408380-6A patent/BRPI0408380A/pt not_active IP Right Cessation
- 2004-03-10 AT AT04719039T patent/ATE417851T1/de active
- 2004-03-10 WO PCT/IT2004/000118 patent/WO2004083214A1/en not_active Ceased
- 2004-03-10 CN CNB2004800071482A patent/CN100372855C/zh not_active Expired - Fee Related
- 2004-03-10 KR KR1020057015243A patent/KR101174112B1/ko not_active Expired - Fee Related
- 2004-03-10 DK DK04719039T patent/DK1603919T3/da active
- 2004-03-10 PL PL04719039T patent/PL1603919T3/pl unknown
- 2004-03-10 EP EP04719039A patent/EP1603919B1/en not_active Expired - Lifetime
- 2004-03-10 SI SI200431027T patent/SI1603919T1/sl unknown
- 2004-03-16 AR ARP040100864A patent/AR043620A1/es not_active Application Discontinuation
-
2009
- 2009-03-17 CY CY20091100298T patent/CY1108890T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR043620A1 (es) | 2005-08-03 |
| KR101174112B1 (ko) | 2012-08-16 |
| AU2004222044A1 (en) | 2004-09-30 |
| WO2004083214A1 (en) | 2004-09-30 |
| HK1089160A1 (zh) | 2006-11-24 |
| CN100372855C (zh) | 2008-03-05 |
| JP4791355B2 (ja) | 2011-10-12 |
| DK1603919T3 (da) | 2009-03-09 |
| US7105492B2 (en) | 2006-09-12 |
| US7351714B2 (en) | 2008-04-01 |
| US20060167033A1 (en) | 2006-07-27 |
| EP1603919A1 (en) | 2005-12-14 |
| PT1603919E (pt) | 2009-02-16 |
| CY1108890T1 (el) | 2014-07-02 |
| CA2517450C (en) | 2011-06-14 |
| AU2004222044B2 (en) | 2010-02-25 |
| CA2517450A1 (en) | 2004-09-30 |
| TW200504076A (en) | 2005-02-01 |
| US20040018988A1 (en) | 2004-01-29 |
| TWI341840B (en) | 2011-05-11 |
| JP2006520807A (ja) | 2006-09-14 |
| PL1603919T3 (pl) | 2009-06-30 |
| CN1761668A (zh) | 2006-04-19 |
| SI1603919T1 (sl) | 2009-04-30 |
| ATE417851T1 (de) | 2009-01-15 |
| BRPI0408380A (pt) | 2006-03-21 |
| KR20050107756A (ko) | 2005-11-15 |
| ES2319293T3 (es) | 2009-05-06 |
| EP1603919B1 (en) | 2008-12-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60327864D1 (de) | Ballondissektor mit kanüle | |
| NO20031447L (no) | Paclitaxel-basert antitumor-formulering | |
| DE602004017700D1 (de) | Transmukosen verabreichung | |
| EP1614160A4 (en) | ELECTROLUMINESCENT DEVICES | |
| ATE482949T1 (de) | N-heterocyclyl-phenylsubstituierte cyclische ketoenole | |
| IS7662A (is) | Ný þríhringlaga spírópíperídín eða spírópýrrólídín | |
| ATE355280T1 (de) | Substituierte dihydrochinazoline mit antiviralen eigenschaften | |
| EP1706546A4 (en) | CURTAINS OF PALPLANCHES WITH LONG EMPTY | |
| DE602004004553D1 (de) | Chinazolinderivate | |
| EP1599196A4 (en) | COMBINATION THERAPIES FOR CANCER TREATMENT | |
| DE602004022180D1 (de) | Chinazolinderivate | |
| ATE450528T1 (de) | Chinazolinderivate als antitumormittel | |
| DE602004016590D1 (de) | Einspritzventil | |
| DE502004011333D1 (de) | Polyalkenamine mit verbesserten anwendungseigenschaften | |
| DE502004012069D1 (de) | Individuelles einstärkenbrillenglas | |
| DE602004005628D1 (de) | Halterung mit mehreren Brücken | |
| DE602004018468D1 (de) | 7-iminoderivate von camptothecin mit antitumorwirkung | |
| DE60328921D1 (de) | Kondom mit integriertem wulstaufbau | |
| ATE504290T1 (de) | Zusammensetzungen mit neramexan | |
| DE502004009781D1 (de) | Einspritzventil | |
| DK1713461T3 (da) | Forbindelser med antitumor-virkning | |
| ATE504278T1 (de) | Hosenförmiger artikel mit verbesserter passform | |
| DE502004005873D1 (de) | Einspritzdüse | |
| ATE417044T1 (de) | 4-amino-chinolin-, -chinolizidinyl- und - chinolizidinylalkylderivate mit antimalariawirkung | |
| SE0303079L (sv) | Dekorativ skiva med ytstruktur |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |