ATE417851T1 - 7-iminoderivate von camptothecin mit antitumorwirkung - Google Patents
7-iminoderivate von camptothecin mit antitumorwirkungInfo
- Publication number
- ATE417851T1 ATE417851T1 AT04719039T AT04719039T ATE417851T1 AT E417851 T1 ATE417851 T1 AT E417851T1 AT 04719039 T AT04719039 T AT 04719039T AT 04719039 T AT04719039 T AT 04719039T AT E417851 T1 ATE417851 T1 AT E417851T1
- Authority
- AT
- Austria
- Prior art keywords
- camptothecin
- tumor effect
- imino derivatives
- imino
- derivatives
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title 1
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/388,587 US7105492B2 (en) | 1999-03-09 | 2003-03-17 | Camptothecin derivatives having antitumor activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE417851T1 true ATE417851T1 (de) | 2009-01-15 |
Family
ID=33029646
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04719039T ATE417851T1 (de) | 2003-03-17 | 2004-03-10 | 7-iminoderivate von camptothecin mit antitumorwirkung |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US7105492B2 (de) |
| EP (1) | EP1603919B1 (de) |
| JP (1) | JP4791355B2 (de) |
| KR (1) | KR101174112B1 (de) |
| CN (1) | CN100372855C (de) |
| AR (1) | AR043620A1 (de) |
| AT (1) | ATE417851T1 (de) |
| AU (1) | AU2004222044B2 (de) |
| BR (1) | BRPI0408380A (de) |
| CA (1) | CA2517450C (de) |
| CY (1) | CY1108890T1 (de) |
| DE (1) | DE602004018468D1 (de) |
| DK (1) | DK1603919T3 (de) |
| ES (1) | ES2319293T3 (de) |
| HK (1) | HK1089160A1 (de) |
| PL (1) | PL1603919T3 (de) |
| PT (1) | PT1603919E (de) |
| SI (1) | SI1603919T1 (de) |
| TW (1) | TWI341840B (de) |
| WO (1) | WO2004083214A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7105492B2 (en) * | 1999-03-09 | 2006-09-12 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
| ITRM20030344A1 (it) * | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
| ITRM20040288A1 (it) * | 2004-06-11 | 2004-09-11 | Sigma Tau Ind Farmaceuti | Uso della 7-t-butossiimminometilcamptotecina per la preparazione di un medicamento per il trattamento delle neoplasie dell'utero. |
| CA2589521C (en) * | 2004-12-15 | 2014-04-01 | Novartis Ag | Combinations of 7-t-butoxyiminomethylcamptothecin with one or more chemotherapeutic agents for treating cancers |
| US7291936B1 (en) * | 2006-05-03 | 2007-11-06 | Robson John H | Submersible electrical power generating plant |
| CN102731516B (zh) * | 2011-04-07 | 2014-07-02 | 宁波天衡药业股份有限公司 | 一类具有抗肿瘤活性的喜树碱衍生物 |
| EP4267140A1 (de) * | 2020-12-23 | 2023-11-01 | Shanghai Ruotuo Biosciences Co., Ltd. | Antikörper-wirkstoff-konjugate, pharmazeutische zusammensetzungen und therapeutische anwendungen |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4399276A (en) | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| JPS58154582A (ja) * | 1982-03-10 | 1983-09-14 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体およびその製造法 |
| ES2204894T3 (es) | 1991-11-15 | 2004-05-01 | Smithkline Beecham Corporation | Composicion que contiene cisplatino y topotecan como agente antitumoral. |
| US5614529A (en) | 1994-09-22 | 1997-03-25 | Research Triangle Institute | Inhibition of plasmodia parasites by camptothecin compounds |
| US5972955A (en) | 1995-06-06 | 1999-10-26 | Dr. Reddy's Research Foundation | Water soluble C-ring analogues of 20(S)-camptothecin |
| IT1282673B1 (it) | 1996-02-23 | 1998-03-31 | Ist Naz Stud Cura Dei Tumori | Derivati della camptotecina e loro uso come agenti antitumorali |
| JP4364305B2 (ja) | 1996-08-19 | 2009-11-18 | バイオニューメリック ファーマシューティカルズ インク | 極めて脂肪親和性のカンプトテシン誘導体 |
| DE69901379T2 (de) * | 1999-03-09 | 2002-11-07 | Sigma Tau Ind Farmaceuti | Camptothecin-Derivate mit Antitumor-Wirkung |
| US7105492B2 (en) * | 1999-03-09 | 2006-09-12 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Camptothecin derivatives having antitumor activity |
-
2003
- 2003-03-17 US US10/388,587 patent/US7105492B2/en not_active Expired - Fee Related
-
2004
- 2004-03-04 TW TW093105744A patent/TWI341840B/zh not_active IP Right Cessation
- 2004-03-10 PL PL04719039T patent/PL1603919T3/pl unknown
- 2004-03-10 KR KR1020057015243A patent/KR101174112B1/ko not_active IP Right Cessation
- 2004-03-10 US US10/546,211 patent/US7351714B2/en not_active Expired - Fee Related
- 2004-03-10 CA CA2517450A patent/CA2517450C/en not_active Expired - Fee Related
- 2004-03-10 AT AT04719039T patent/ATE417851T1/de active
- 2004-03-10 AU AU2004222044A patent/AU2004222044B2/en not_active Ceased
- 2004-03-10 EP EP04719039A patent/EP1603919B1/de not_active Expired - Lifetime
- 2004-03-10 DE DE602004018468T patent/DE602004018468D1/de not_active Expired - Lifetime
- 2004-03-10 DK DK04719039T patent/DK1603919T3/da active
- 2004-03-10 BR BRPI0408380-6A patent/BRPI0408380A/pt not_active IP Right Cessation
- 2004-03-10 SI SI200431027T patent/SI1603919T1/sl unknown
- 2004-03-10 PT PT04719039T patent/PT1603919E/pt unknown
- 2004-03-10 JP JP2006507637A patent/JP4791355B2/ja not_active Expired - Fee Related
- 2004-03-10 CN CNB2004800071482A patent/CN100372855C/zh not_active Expired - Fee Related
- 2004-03-10 ES ES04719039T patent/ES2319293T3/es not_active Expired - Lifetime
- 2004-03-10 WO PCT/IT2004/000118 patent/WO2004083214A1/en active Application Filing
- 2004-03-16 AR ARP040100864A patent/AR043620A1/es not_active Application Discontinuation
-
2006
- 2006-08-25 HK HK06109464A patent/HK1089160A1/xx not_active IP Right Cessation
-
2009
- 2009-03-17 CY CY20091100298T patent/CY1108890T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20050107756A (ko) | 2005-11-15 |
| PT1603919E (pt) | 2009-02-16 |
| DK1603919T3 (da) | 2009-03-09 |
| WO2004083214A1 (en) | 2004-09-30 |
| KR101174112B1 (ko) | 2012-08-16 |
| EP1603919B1 (de) | 2008-12-17 |
| JP2006520807A (ja) | 2006-09-14 |
| BRPI0408380A (pt) | 2006-03-21 |
| CA2517450A1 (en) | 2004-09-30 |
| CN100372855C (zh) | 2008-03-05 |
| US7105492B2 (en) | 2006-09-12 |
| US7351714B2 (en) | 2008-04-01 |
| SI1603919T1 (sl) | 2009-04-30 |
| ES2319293T3 (es) | 2009-05-06 |
| CA2517450C (en) | 2011-06-14 |
| US20040018988A1 (en) | 2004-01-29 |
| AR043620A1 (es) | 2005-08-03 |
| CY1108890T1 (el) | 2014-07-02 |
| PL1603919T3 (pl) | 2009-06-30 |
| TW200504076A (en) | 2005-02-01 |
| AU2004222044A1 (en) | 2004-09-30 |
| TWI341840B (en) | 2011-05-11 |
| DE602004018468D1 (de) | 2009-01-29 |
| CN1761668A (zh) | 2006-04-19 |
| AU2004222044B2 (en) | 2010-02-25 |
| US20060167033A1 (en) | 2006-07-27 |
| EP1603919A1 (de) | 2005-12-14 |
| JP4791355B2 (ja) | 2011-10-12 |
| HK1089160A1 (en) | 2006-11-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE216998T1 (de) | Camptothecin-derivate mit antitumor-wirkung | |
| ATE450528T1 (de) | Chinazolinderivate als antitumormittel | |
| DE602004020183D1 (de) | Schrittmacher mit av-intervall-optimierung | |
| IS7939A (is) | Pýrasólpýridín afleiður | |
| DK1594840T3 (da) | Piperidin-benzensulfonamid-derivater | |
| NO20054136D0 (no) | Imidazol-4-yl-etynyl-pyridin-derivater | |
| DE60327864D1 (de) | Ballondissektor mit kanüle | |
| ATE420066T1 (de) | Amidoacetonitrilderivate | |
| NO20053782D0 (no) | Behandling av kreft med 2-deoksyglukose | |
| DE602004004553D1 (de) | Chinazolinderivate | |
| ATE478870T1 (de) | Spiroindolinpiperidinderivate | |
| ATE460418T1 (de) | Heterocyclocarboxamidderivate | |
| ATE450506T1 (de) | Indol-3-schwefelderivate | |
| ATE467631T1 (de) | Chinuclidinamidderivate | |
| IS7720A (is) | Píperidín-N-oxíð-afleiður | |
| ATE438644T1 (de) | Chinazolinderivate | |
| DK2248807T3 (da) | N-Phenyl-2-pyrimidinaminderivater | |
| NO20055649D0 (no) | Substituert dihydrokinazolin med antiviale egenskaper | |
| DK2275439T3 (da) | Hidtil ukendte insulinderivater | |
| ATE512148T1 (de) | Pyrazolo- und imidazopyrimidinderivate | |
| ATE335729T1 (de) | 3h-chinazoline -4-on derivaten | |
| ATE354365T1 (de) | N-thiazol-2-yl-benzamid-derivate | |
| ATE423771T1 (de) | Tetrahydrochinolinderivate | |
| DE60321752D1 (de) | Halterung mit rotationssymmetrischen Taschen | |
| ATE417851T1 (de) | 7-iminoderivate von camptothecin mit antitumorwirkung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1603919 Country of ref document: EP |