PL147393B1 - Method of obtaining novel derivatives of three-ring oxindolocarbonamide - Google Patents

Method of obtaining novel derivatives of three-ring oxindolocarbonamide Download PDF

Info

Publication number
PL147393B1
PL147393B1 PL1985255089A PL25508985A PL147393B1 PL 147393 B1 PL147393 B1 PL 147393B1 PL 1985255089 A PL1985255089 A PL 1985255089A PL 25508985 A PL25508985 A PL 25508985A PL 147393 B1 PL147393 B1 PL 147393B1
Authority
PL
Poland
Prior art keywords
arh
formula
group
nch2
och2
Prior art date
Application number
PL1985255089A
Other languages
English (en)
Polish (pl)
Other versions
PL255089A1 (en
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL255089A1 publication Critical patent/PL255089A1/xx
Publication of PL147393B1 publication Critical patent/PL147393B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
PL1985255089A 1984-08-24 1985-08-22 Method of obtaining novel derivatives of three-ring oxindolocarbonamide PL147393B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001371 WO1986001510A1 (en) 1984-08-24 1984-08-24 Tricyclic oxindole antiinflammatory agents

Publications (2)

Publication Number Publication Date
PL255089A1 PL255089A1 (en) 1986-12-30
PL147393B1 true PL147393B1 (en) 1989-05-31

Family

ID=22182243

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1985255089A PL147393B1 (en) 1984-08-24 1985-08-22 Method of obtaining novel derivatives of three-ring oxindolocarbonamide
PL1985260270A PL147395B1 (en) 1984-08-24 1985-08-22 Method of obtaining novel derivatives of three-ring oxyindolocarbonamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1985260270A PL147395B1 (en) 1984-08-24 1985-08-22 Method of obtaining novel derivatives of three-ring oxyindolocarbonamide

Country Status (21)

Country Link
US (1) US4695571A (enExample)
EP (1) EP0173520B1 (enExample)
JP (1) JPS6157554A (enExample)
KR (1) KR870001144B1 (enExample)
AT (1) ATE49211T1 (enExample)
AU (1) AU553859B2 (enExample)
CA (1) CA1244427A (enExample)
DE (1) DE3575140D1 (enExample)
DK (1) DK160098C (enExample)
EG (1) EG17287A (enExample)
ES (2) ES8704497A1 (enExample)
FI (1) FI79319C (enExample)
GR (1) GR852026B (enExample)
HU (2) HU203350B (enExample)
IE (1) IE58739B1 (enExample)
IL (1) IL76175A (enExample)
PH (1) PH23065A (enExample)
PL (2) PL147393B1 (enExample)
PT (1) PT81004B (enExample)
WO (1) WO1986001510A1 (enExample)
ZA (1) ZA856403B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS63223492A (ja) * 1987-03-11 1988-09-16 Okawara Mfg Co Ltd 熱交換器
WO1990008146A1 (en) * 1989-01-10 1990-07-26 Pfizer Inc. Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides
WO1990008145A1 (en) * 1989-01-10 1990-07-26 Pfizer Inc. Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles
US5300655A (en) * 1989-04-18 1994-04-05 Pfizer Inc. 2-carboxy-thiophene derivatives
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
JPH04217684A (ja) * 1990-05-30 1992-08-07 Shionogi & Co Ltd アルド−ス還元酵素阻害物質
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2005041957A1 (en) * 2003-10-29 2005-05-12 Pfizer Products Inc. Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756447A (fr) * 1969-10-15 1971-03-22 Pfizer Oxindolecarboxamides
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US4644005A (en) * 1984-10-31 1987-02-17 Pfizer Inc. Oxindole antiinflammatory agents

Also Published As

Publication number Publication date
PH23065A (en) 1989-03-27
PL255089A1 (en) 1986-12-30
ZA856403B (en) 1987-04-29
KR870002143A (ko) 1987-03-30
FI79319B (fi) 1989-08-31
HU902020D0 (en) 1990-07-28
JPH0450316B2 (enExample) 1992-08-13
DK160098B (da) 1991-01-28
IE58739B1 (en) 1993-11-03
HU203238B (en) 1991-06-28
FI861704A7 (fi) 1986-04-23
ES546377A0 (es) 1987-04-01
IL76175A (en) 1989-08-15
PT81004B (pt) 1987-12-30
ES8706116A1 (es) 1987-06-01
GR852026B (enExample) 1985-12-19
US4695571A (en) 1987-09-22
DK382685A (da) 1986-02-25
HU203350B (en) 1991-07-29
KR870001144B1 (ko) 1987-06-11
CA1244427A (en) 1988-11-08
DK382685D0 (da) 1985-08-23
AU553859B2 (en) 1986-07-31
IE852081L (en) 1986-02-24
ES552044A0 (es) 1987-06-01
PL147395B1 (en) 1989-05-31
IL76175A0 (en) 1985-12-31
FI861704A0 (fi) 1986-04-23
EP0173520B1 (en) 1990-01-03
JPS6157554A (ja) 1986-03-24
ES8704497A1 (es) 1987-04-01
DK160098C (da) 1991-06-24
AU4663785A (en) 1986-02-27
ATE49211T1 (de) 1990-01-15
HUT47580A (en) 1989-03-28
EP0173520A2 (en) 1986-03-05
WO1986001510A1 (en) 1986-03-13
FI79319C (fi) 1989-12-11
PT81004A (en) 1985-09-01
EP0173520A3 (en) 1986-05-14
DE3575140D1 (de) 1990-02-08
EG17287A (en) 1993-02-28

Similar Documents

Publication Publication Date Title
PL147393B1 (en) Method of obtaining novel derivatives of three-ring oxindolocarbonamide
US4522944A (en) Carboxamido-derivatives of 5H-1,3,4-thiadiazolo[3,2-a]pyrimidines, compositions and use
AU706110B2 (en) Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents
CA3125900A1 (en) 15-pgdh inhibitor
JPWO1992012966A1 (ja) ３−ベンジリデン−１−カルバモイル−２−ピロリドン類縁体
SE456582B (sv) Mellanprodukter for framstellning av 3,4-disubstituerade 1,2,5-tiadiazol-1-oxider och -1,1-dioxider, som er h 71-receptorantagonister
CA2137976A1 (en) Thienothiazine derivatives
EP0535521A2 (en) Condensed oxazole and thiazole derivatives as leukotriene biosynthesis inhibitors
WO2004056789A1 (en) Mek inhibiting oxa- and thia-diazol-2-yl phenylamine derivates
TW201925173A (zh) 鹵代烯丙基胺類ssao/vap-1抑制劑及其用途
PT605228E (pt) Derivados tiazolidinadionas sua preparacao e sua utilizacao
CA2075673A1 (en) (2-alkyl-3-pyridyl)methylpiperazine derivatives
EP0091726A2 (en) 5-Substituted 1,2,4-oxadiazole derivatives, their preparation and pharmaceutical compositions containing them
AU1711999A (en) Acyl guanidine sodium/proton exchange inhibitors and method
PL150842B1 (en) Method of obtaining 2-ketoindolo-3-carbonamides
CA2034546C (en) 1, 3-dicarbonyl compounds and their use
AU767923B2 (en) Novel 2-(N-cyanoimino)thiazolidin-4-one derivatives
Smith et al. Organotellurium chemistry: synthesis and properties of 2-acylamino-and 2-arylamino-1, 3-benzotellurazoles
EP0748317A1 (en) Novel thiazolidin-4-one derivatives
Wang et al. Design, synthesis and biological evaluation of nitrofuran-1, 3, 4-oxadiazole hybrids as new antitubercular agents
US4684658A (en) Anti-thrombotic ortho-condensed pyrrole derivatives, compositions, and method of use therefor
RU2055073C1 (ru) Производные тиазолидинона или оксазолидинона и способ их получения
FI93108C (fi) Menetelmä lääkeaineina käyttökelpoisten 2-bentsotiatsoliinijohdannaisten valmistamiseksi
JP2008524139A (ja) メタ置換チアゾリノン類、それらの製造及び医薬としての使用
JP2668259B2 (ja) 複素環化合物および抗潰瘍剤