PL128539B1 - Method of obtaining a platinum complex - Google Patents

Method of obtaining a platinum complex Download PDF

Info

Publication number
PL128539B1
PL128539B1 PL1981230896A PL23089681A PL128539B1 PL 128539 B1 PL128539 B1 PL 128539B1 PL 1981230896 A PL1981230896 A PL 1981230896A PL 23089681 A PL23089681 A PL 23089681A PL 128539 B1 PL128539 B1 PL 128539B1
Authority
PL
Poland
Prior art keywords
phic
dose
platinum
compound
day
Prior art date
Application number
PL1981230896A
Other languages
English (en)
Polish (pl)
Other versions
PL230896A1 (en, 2012
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PL230896A1 publication Critical patent/PL230896A1/xx
Publication of PL128539B1 publication Critical patent/PL128539B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/245Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL1981230896A 1980-04-29 1981-04-28 Method of obtaining a platinum complex PL128539B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8014109 1980-04-29

Publications (2)

Publication Number Publication Date
PL230896A1 PL230896A1 (en, 2012) 1982-01-04
PL128539B1 true PL128539B1 (en) 1984-02-29

Family

ID=10513074

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1981230896A PL128539B1 (en) 1980-04-29 1981-04-28 Method of obtaining a platinum complex

Country Status (32)

Country Link
US (1) US4452812A (en, 2012)
EP (1) EP0039272B1 (en, 2012)
JP (1) JPS595599B2 (en, 2012)
AR (1) AR226354A1 (en, 2012)
AT (1) AT372072B (en, 2012)
AU (1) AU6978681A (en, 2012)
BE (1) BE888367A (en, 2012)
CA (1) CA1171425A (en, 2012)
DD (1) DD158777A5 (en, 2012)
DE (1) DE3163162D1 (en, 2012)
DK (1) DK188481A (en, 2012)
ES (1) ES8203324A1 (en, 2012)
FI (1) FI811314L (en, 2012)
FR (1) FR2481289B1 (en, 2012)
GB (1) GB2077720B (en, 2012)
GR (1) GR75598B (en, 2012)
IE (1) IE51197B1 (en, 2012)
IL (1) IL62615A0 (en, 2012)
IT (1) IT1146749B (en, 2012)
JO (1) JO1176B1 (en, 2012)
LU (1) LU83325A1 (en, 2012)
MA (1) MA19131A1 (en, 2012)
MC (1) MC1391A1 (en, 2012)
NO (1) NO811449L (en, 2012)
NZ (1) NZ196803A (en, 2012)
OA (1) OA06797A (en, 2012)
PL (1) PL128539B1 (en, 2012)
PT (1) PT72941B (en, 2012)
RO (1) RO82032B (en, 2012)
YU (1) YU102581A (en, 2012)
ZA (1) ZA812474B (en, 2012)
ZW (1) ZW8681A1 (en, 2012)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112995A (ja) * 1982-12-21 1984-06-29 Shionogi & Co Ltd 新規グリコ−ル酸白金錯体
AU558747B2 (en) * 1983-05-10 1987-02-05 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
JPS6013795A (ja) * 1983-06-20 1985-01-24 リサ−チ・コ−ポレイシヨン ジアミノシクロヘキサン白金錯体
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
ATE49214T1 (de) * 1984-12-17 1990-01-15 American Cyanamid Co Platinkomplexe von aliphatischen tricarbonsaeuren.
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1283904C (en) * 1987-03-06 1991-05-07 Mitsuaki Maeda Liposoluble platinum (ii) complex and preparation thereof
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
ATE143967T1 (de) * 1989-12-12 1996-10-15 Toray Industries Neuer platin(ii)komplex und mittel für die behandlung von bösartigen tumoren
JP3154399B2 (ja) * 1996-07-04 2001-04-09 デビオファーム エス.アー. 白金化合物の製造方法
US6689928B2 (en) 2000-04-04 2004-02-10 Exxonmobil Research And Engineering Company Transition metal complexes and oligomers therefrom
DE10206648A1 (de) * 2002-02-15 2003-09-11 November Ag Molekulare Medizin Wirkstoff zur Herstellung eines Stoffs zur Beeinflussung der Koagulationsbereitschaft des Bluts
RU2335512C2 (ru) * 2003-12-10 2008-10-10 Тоудаи Тло, Лтд. Координационный комплекс диаминоциклогексана платины (ii) с блоксополимером, содержащим сегмент поли(карбоновой кислоты), и включающий его противораковый агент
DE102004005906B3 (de) * 2004-02-05 2005-09-29 W.C. Heraeus Gmbh Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2006098496A1 (ja) * 2005-03-18 2006-09-21 The University Of Tokyo ジアミノシクロヘキサン白金(ii)とブロック共重合体との配位化合物及びそれを含有する抗がん剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (en, 2012) * 1972-06-08 1978-09-29 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt

Also Published As

Publication number Publication date
BE888367A (fr) 1981-07-31
FI811314A7 (fi) 1981-10-30
IT1146749B (it) 1986-11-19
RO82032A (ro) 1984-01-14
PT72941B (fr) 1982-03-30
AU6978681A (en) 1981-11-05
EP0039272B1 (fr) 1984-04-18
GR75598B (en, 2012) 1984-08-01
IL62615A0 (en) 1981-06-29
GB2077720B (en) 1983-09-07
ATA191981A (de) 1983-01-15
ZA812474B (en) 1982-05-26
ZW8681A1 (en) 1981-07-08
RO82032B (ro) 1984-01-30
GB2077720A (en) 1981-12-23
DD158777A5 (de) 1983-02-02
FR2481289B1 (fr) 1985-06-14
MA19131A1 (fr) 1981-12-31
FR2481289A1 (fr) 1981-10-30
CA1171425A (en) 1984-07-24
IT8167555A0 (it) 1981-04-23
EP0039272A3 (en) 1982-05-05
FI811314L (fi) 1981-10-30
ES502411A0 (es) 1982-04-01
LU83325A1 (fr) 1981-07-24
OA06797A (fr) 1982-12-31
JO1176B1 (en) 1983-11-30
EP0039272A2 (fr) 1981-11-04
PT72941A (fr) 1981-05-01
YU102581A (en) 1983-09-30
JPS572296A (en) 1982-01-07
NO811449L (no) 1981-10-30
DK188481A (da) 1981-10-30
JPS595599B2 (ja) 1984-02-06
AT372072B (de) 1983-08-25
AR226354A1 (es) 1982-06-30
IE51197B1 (en) 1986-10-29
MC1391A1 (fr) 1982-04-27
DE3163162D1 (en) 1984-10-04
PL230896A1 (en, 2012) 1982-01-04
NZ196803A (en) 1983-12-16
US4452812A (en) 1984-06-05
IE810925L (en) 1981-10-29
ES8203324A1 (es) 1982-04-01

Similar Documents

Publication Publication Date Title
PL128539B1 (en) Method of obtaining a platinum complex
Guo et al. Metals in medicine
CA1261864A (en) Liposoluble platinum (ii) complex and preparation thereof
SU886748A3 (ru) Способ получени антрациклиновых гликозидов
CA2370692C (en) Antitumor derivative of double dicarboxylic acid diaminoplatin complex, process for the preparing thereof, the pharmaceutical composition containing the same and application of the derivative
US5041578A (en) Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
EP0057023A1 (en) Novel platinum complexes
US4584392A (en) Platinum and palladium complexes
Barnham et al. [Pt (CBDCA-O)(NH3) 2 (L-Methionine-S)]: Ring-Opened Adduct of the Anticancer Drug Carboplatin (" Paraplatin"). Detection of a Similar Complex in Urine by NMR Spectroscopy
Ouyang et al. Potent saccharinate-containing palladium (II) complexes for sensitization to cancer therapy
US5393909A (en) Diamine platinum complexes as antitumor agents
EP0333756B1 (en) 1,2-diaminocyclohexane-platinum complexes with antitumor activity
Den Hartog et al. Coordination of 9-methylhypoxanthine to [cis-Pt (NH3) 2] 2+ and [Pt (dien)] 2+ as studied by proton NMR
JPH02108693A (ja) 白金(4)ジアミン錯体
Meshnick et al. Capacity of a cis-diammineplatinum [II]-polyglutamic acid complex to cure Trypanosoma congolense infections in mice
CN109550053A (zh) 一种双药配位聚合物抗结核纳米药物的制备方法
CN101723982B (zh) 具有抗癌活性的合铂化合物及其合成方法
WO1996026730A1 (en) Use of acid-sensitive organo- transition metal compounds in cancer treatment
CN119033753B (zh) 一种环二烯铂配合物在制备抗耐药型真菌药物中的应用
US8703756B2 (en) Synthetic procedure and cancer treatment with cisplatin derivatives
Wang et al. Acetylated monosaccharide functionalized co-ligand based strong anticancer Pt (II) complexes: Synthesis characterization and biological analyses
NO172184B (no) Analogifremgangsmaate til fremstilling av medisinsk virkende platinakomplekser med antisvulstvirkning
KR810000983B1 (ko) 안스라싸이클린 글리코시드(Anthracycline Glycoside)의 제조방법
Reddy The Synthesis of Functionalized Glycosides: Coordination Chemistry, Antiparasitic Activity, Precursors to Conformationally Constrained Macrocyclic Architectures and Photophysical Properties
Noji et al. Synthesis of Pt (II) complexes containing d-glucuronate, d-gluconate, or their acetyl derivatives and evaluation of antitumor activity against murine leukemia L1210