RO82032B - Procedeu pentru prepararea cis-izocitratului de (1, 2-diaminociclohexan)platina - Google Patents

Procedeu pentru prepararea cis-izocitratului de (1, 2-diaminociclohexan)platina

Info

Publication number
RO82032B
RO82032B RO104130A RO10413081A RO82032B RO 82032 B RO82032 B RO 82032B RO 104130 A RO104130 A RO 104130A RO 10413081 A RO10413081 A RO 10413081A RO 82032 B RO82032 B RO 82032B
Authority
RO
Romania
Prior art keywords
platinum
cis
preparation
izocitrate
diaminocyclohexan
Prior art date
Application number
RO104130A
Other languages
English (en)
Romanian (ro)
Other versions
RO82032A (ro
Inventor
Pierre-Jean Macquet
Original Assignee
Sanofi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi filed Critical Sanofi
Publication of RO82032A publication Critical patent/RO82032A/ro
Publication of RO82032B publication Critical patent/RO82032B/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RO104130A 1980-04-29 1981-04-27 Procedeu pentru prepararea cis-izocitratului de (1, 2-diaminociclohexan)platina RO82032B (ro)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8014109 1980-04-29

Publications (2)

Publication Number Publication Date
RO82032A RO82032A (ro) 1984-01-14
RO82032B true RO82032B (ro) 1984-01-30

Family

ID=10513074

Family Applications (1)

Application Number Title Priority Date Filing Date
RO104130A RO82032B (ro) 1980-04-29 1981-04-27 Procedeu pentru prepararea cis-izocitratului de (1, 2-diaminociclohexan)platina

Country Status (32)

Country Link
US (1) US4452812A (en, 2012)
EP (1) EP0039272B1 (en, 2012)
JP (1) JPS595599B2 (en, 2012)
AR (1) AR226354A1 (en, 2012)
AT (1) AT372072B (en, 2012)
AU (1) AU6978681A (en, 2012)
BE (1) BE888367A (en, 2012)
CA (1) CA1171425A (en, 2012)
DD (1) DD158777A5 (en, 2012)
DE (1) DE3163162D1 (en, 2012)
DK (1) DK188481A (en, 2012)
ES (1) ES8203324A1 (en, 2012)
FI (1) FI811314L (en, 2012)
FR (1) FR2481289B1 (en, 2012)
GB (1) GB2077720B (en, 2012)
GR (1) GR75598B (en, 2012)
IE (1) IE51197B1 (en, 2012)
IL (1) IL62615A0 (en, 2012)
IT (1) IT1146749B (en, 2012)
JO (1) JO1176B1 (en, 2012)
LU (1) LU83325A1 (en, 2012)
MA (1) MA19131A1 (en, 2012)
MC (1) MC1391A1 (en, 2012)
NO (1) NO811449L (en, 2012)
NZ (1) NZ196803A (en, 2012)
OA (1) OA06797A (en, 2012)
PL (1) PL128539B1 (en, 2012)
PT (1) PT72941B (en, 2012)
RO (1) RO82032B (en, 2012)
YU (1) YU102581A (en, 2012)
ZA (1) ZA812474B (en, 2012)
ZW (1) ZW8681A1 (en, 2012)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59112995A (ja) * 1982-12-21 1984-06-29 Shionogi & Co Ltd 新規グリコ−ル酸白金錯体
AU558747B2 (en) * 1983-05-10 1987-02-05 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
US4720504A (en) * 1983-05-10 1988-01-19 Andrulis Research Corporation Use of bis-platinum complexes as antitumor agents
JPS6013795A (ja) * 1983-06-20 1985-01-24 リサ−チ・コ−ポレイシヨン ジアミノシクロヘキサン白金錯体
US4661516A (en) * 1983-06-20 1987-04-28 Research Corporation Diaminocyclohexane platinum complexes
US4758588A (en) * 1983-06-20 1988-07-19 Research Corporation Technologies Diaminocyclohexane platinum complexes
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
EP0169645A1 (en) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Platinum co-ordination compounds
ATE49214T1 (de) * 1984-12-17 1990-01-15 American Cyanamid Co Platinkomplexe von aliphatischen tricarbonsaeuren.
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
CA1283904C (en) * 1987-03-06 1991-05-07 Mitsuaki Maeda Liposoluble platinum (ii) complex and preparation thereof
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
ATE143967T1 (de) * 1989-12-12 1996-10-15 Toray Industries Neuer platin(ii)komplex und mittel für die behandlung von bösartigen tumoren
JP3154399B2 (ja) * 1996-07-04 2001-04-09 デビオファーム エス．アー． 白金化合物の製造方法
US6689928B2 (en) 2000-04-04 2004-02-10 Exxonmobil Research And Engineering Company Transition metal complexes and oligomers therefrom
DE10206648A1 (de) * 2002-02-15 2003-09-11 November Ag Molekulare Medizin Wirkstoff zur Herstellung eines Stoffs zur Beeinflussung der Koagulationsbereitschaft des Bluts
RU2335512C2 (ru) * 2003-12-10 2008-10-10 Тоудаи Тло, Лтд. Координационный комплекс диаминоциклогексана платины (ii) с блоксополимером, содержащим сегмент поли(карбоновой кислоты), и включающий его противораковый агент
DE102004005906B3 (de) * 2004-02-05 2005-09-29 W.C. Heraeus Gmbh Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
WO2006098496A1 (ja) * 2005-03-18 2006-09-21 The University Of Tokyo ジアミノシクロヘキサン白金(ii)とブロック共重合体との配位化合物及びそれを含有する抗がん剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (en, 2012) * 1972-06-08 1978-09-29 Research Corp
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
SE447902B (sv) * 1977-10-19 1986-12-22 Johnson Matthey Co Ltd Cis-koordinationsforening av platina och komposition innehallande foreningen
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt

Also Published As

Publication number Publication date
BE888367A (fr) 1981-07-31
FI811314A7 (fi) 1981-10-30
IT1146749B (it) 1986-11-19
RO82032A (ro) 1984-01-14
PT72941B (fr) 1982-03-30
AU6978681A (en) 1981-11-05
EP0039272B1 (fr) 1984-04-18
GR75598B (en, 2012) 1984-08-01
IL62615A0 (en) 1981-06-29
GB2077720B (en) 1983-09-07
ATA191981A (de) 1983-01-15
ZA812474B (en) 1982-05-26
ZW8681A1 (en) 1981-07-08
GB2077720A (en) 1981-12-23
DD158777A5 (de) 1983-02-02
FR2481289B1 (fr) 1985-06-14
MA19131A1 (fr) 1981-12-31
FR2481289A1 (fr) 1981-10-30
CA1171425A (en) 1984-07-24
IT8167555A0 (it) 1981-04-23
EP0039272A3 (en) 1982-05-05
FI811314L (fi) 1981-10-30
ES502411A0 (es) 1982-04-01
LU83325A1 (fr) 1981-07-24
OA06797A (fr) 1982-12-31
PL128539B1 (en) 1984-02-29
JO1176B1 (en) 1983-11-30
EP0039272A2 (fr) 1981-11-04
PT72941A (fr) 1981-05-01
YU102581A (en) 1983-09-30
JPS572296A (en) 1982-01-07
NO811449L (no) 1981-10-30
DK188481A (da) 1981-10-30
JPS595599B2 (ja) 1984-02-06
AT372072B (de) 1983-08-25
AR226354A1 (es) 1982-06-30
IE51197B1 (en) 1986-10-29
MC1391A1 (fr) 1982-04-27
DE3163162D1 (en) 1984-10-04
PL230896A1 (en, 2012) 1982-01-04
NZ196803A (en) 1983-12-16
US4452812A (en) 1984-06-05
IE810925L (en) 1981-10-29
ES8203324A1 (es) 1982-04-01

Similar Documents

Publication Publication Date Title
RO82032B (ro) Procedeu pentru prepararea cis-izocitratului de (1, 2-diaminociclohexan)platina
FR2422637A1 (fr) Nouveaux derives de l'acide 2(4-thio-2-oxo-azetidin-1-yl)-3-methylene-butyrique et procede de preparation
MX171822B (es) Proceso quimico
ATE48605T1 (de) Antitumor-platin-komplexe.
FR2355016A1 (fr) Acide monique
FR2357556A1 (fr) Procede de transformation de cis-hexahydrodibenzo(b,d) pyran-9-ones en trans-hexahydrodibenzo(b,d) pyran-9-ones
RO84317B (ro) Procedeu de preparare a unor derivati de difenileter cu activitate erbicida
GB1504651A (en) Phosphonates
RO82467B (ro) Procedeu pentru prepararea unor 4h-1, 3-tiazin-4-one
FR2421914A1 (fr) 3-acetoxy-9b-11b-epoxy-pregna-trienes et dienes et procede de preparation de 6a-halogeno-pregna-1,4-diene-3 ones et de 6a halogeno-pregna-4-ene-3-ones correspondants
FR2381733A1 (fr) Procede de preparation de m-bromo-a,a,a-trifluorotoluenes
FR2383931A1 (fr) Derives d'oxadiazolopyrimidine
AR248029A1 (es) Un procedimiento para la preparacion de n-fosfonometilglicina.
AR240813A2 (es) N-fenilsulfonil-n'-pirimidinilureas, procedimiento para su preparacion, composiciones que las contienen e intermediarios para uso exclusivo en dicho procedimiento
RO86246B (ro) Procedeu pentru prepararea 5-(dihidroxifenoxi)-tetrazolilor
RO70668B (ro) Procedeu pentru prepararea unor compusi de 4-(4-bifenili)-butanol
FR2433009A1 (fr) Procede pour la preparation de dicyclopentylene(2,2'-bis(4-alkyl-6-t-butylphenols))
FR2378737A1 (fr) Nouveaux cyclohexanes substitues utiles comme agents olfactifs
RO82035B (ro) Procedeu pentru prepararea unor derivati 1-oxa-beta-lactamici
FR2377387A1 (fr) Procede de preparation de 2,4,5-trichloropyrimidine
RO86323B1 (ro) Procedeu pentru prepararea unor compusi organofosforici pirimidinil substituiti
FR2389618A1 (en, 2012)
RO83980B1 (ro) Derivat de 1, 1'-oxi-bis-(2-clor-4n-benzamido)-benzen
FR2357555A1 (fr) Procede de preparation de cis-hexahydrodibenzopyranones
TH2026A (th) กระบวนการสำหรับผลิตกรด n-ฟอสโฟโนเมทธิลไกลซึน