PL119586B1 - Process for preparing novel derivatives of 4-amino-2-piperazyn-1-yl-or homopiperazyn-1-yl-quinazolineinil-1-ili gomopiperazinil-1 khinazolina - Google Patents

Process for preparing novel derivatives of 4-amino-2-piperazyn-1-yl-or homopiperazyn-1-yl-quinazolineinil-1-ili gomopiperazinil-1 khinazolina Download PDF

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Publication number
PL119586B1
PL119586B1 PL1978210681A PL21068178A PL119586B1 PL 119586 B1 PL119586 B1 PL 119586B1 PL 1978210681 A PL1978210681 A PL 1978210681A PL 21068178 A PL21068178 A PL 21068178A PL 119586 B1 PL119586 B1 PL 119586B1
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PL
Poland
Prior art keywords
formula
group
amino
groups
compounds
Prior art date
Application number
PL1978210681A
Other languages
English (en)
Polish (pl)
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PL210681A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Simon Fraser Campbell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PL210681A1 publication Critical patent/PL210681A1/xx
Publication of PL119586B1 publication Critical patent/PL119586B1/pl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/201,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL1978210681A 1977-11-05 1978-11-03 Process for preparing novel derivatives of 4-amino-2-piperazyn-1-yl-or homopiperazyn-1-yl-quinazolineinil-1-ili gomopiperazinil-1 khinazolina PL119586B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4612877 1977-11-05

Publications (2)

Publication Number Publication Date
PL210681A1 PL210681A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-11-05
PL119586B1 true PL119586B1 (en) 1982-01-30

Family

ID=10439957

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1978210681A PL119586B1 (en) 1977-11-05 1978-11-03 Process for preparing novel derivatives of 4-amino-2-piperazyn-1-yl-or homopiperazyn-1-yl-quinazolineinil-1-ili gomopiperazinil-1 khinazolina
PL1978216980A PL119419B1 (en) 1977-11-05 1978-11-03 Process for preparing novel derivatives of 4-amino-2-/piperazin-1-yl or homopiperazin-1-yl/-quinazolinenil-1/ili gomopiperazinil-1 khinazolina

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1978216980A PL119419B1 (en) 1977-11-05 1978-11-03 Process for preparing novel derivatives of 4-amino-2-/piperazin-1-yl or homopiperazin-1-yl/-quinazolinenil-1/ili gomopiperazinil-1 khinazolina

Country Status (36)

Country Link
JP (1) JPS5498792A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (2) AR219562A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT365186B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU509329B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE871771A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1088059A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH643255A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (2) CS207671B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD139850A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2847623C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK154082C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EG (1) EG13594A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES474805A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI64366C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2407929A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR81514B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HK (1) HK94284A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU176306B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE47888B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL55857A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IN (1) IN148828B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1100919B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KE (1) KE3350A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
LU (2) LU80470A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MY (1) MY8500286A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (2) NL174549C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO150158C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ188813A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH13966A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (2) PL119586B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT68735A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE437518B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU816403A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
UA (1) UA8324A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (2) YU40204B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA786184B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986002644A1 (en) * 1984-11-01 1986-05-09 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1985002617A1 (en) * 1983-12-14 1985-06-20 Takeda Chemical Industries. Ltd. 1,5-benzoxathiepin derivatives and process for their preparation
WO1985004658A1 (en) * 1984-04-04 1985-10-24 Takeda Chemical Industries, Ltd. 1,5-benzoxathiepine derivatives and their preparation
EP0849265A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von Doxazosin-Mesylat (Form II)
EP0849264A1 (de) * 1996-12-20 1998-06-24 HEUMANN PHARMA GmbH Neue polymorphe Form von doxazosinmesylat (Form I)
ES2282997T3 (es) * 1996-12-20 2007-10-16 Heumann Pcs Gmbh Nueva forma polimorfa de mesilato e doxazosina (forma iii).
TW448155B (en) * 1999-03-29 2001-08-01 Dev Center Biotechnology Method for producing amide compounds and quinazolin derivatives
EP1403263B1 (en) * 2002-09-27 2005-06-22 Council of Scientific and Industrial Research Process for the preparation of N-(2,3-dihydrobenzo 1,4 dioxin-2-carbonyl) piperazine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3663706A (en) * 1969-09-29 1972-05-16 Pfizer Use of 2,4-diaminoquinazolines as hypotensive agents
US3669968A (en) * 1970-05-21 1972-06-13 Pfizer Trialkoxy quinazolines

Also Published As

Publication number Publication date
PH13966A (en) 1980-11-12
SE437518B (sv) 1985-03-04
FR2407929B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-02-27
DK428678A (da) 1979-05-06
YU40204B (en) 1985-08-31
NO150158C (no) 1984-08-29
UA8324A1 (uk) 1996-03-29
NL7810909A (nl) 1979-05-08
ATA784378A (de) 1981-05-15
DE2847623A1 (de) 1979-05-23
IN148828B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-27
CS354491A3 (en) 1992-06-17
ES8308559A1 (es) 1980-07-16
PL119419B1 (en) 1981-12-31
FI64366C (fi) 1983-11-10
LU88331I2 (fr) 1994-05-04
YU255378A (en) 1983-06-30
ZA786184B (en) 1979-10-31
MY8500286A (en) 1985-12-31
DK154082B (da) 1988-10-10
IL55857A (en) 1982-07-30
HK94284A (en) 1984-12-07
IE47888B1 (en) 1984-07-11
FI783347A7 (fi) 1979-05-06
DK154082C (da) 1989-02-27
NO150158B (no) 1984-05-21
NL174549C (nl) 1984-07-02
CA1088059A (en) 1980-10-21
AT365186B (de) 1981-12-28
PT68735A (en) 1978-12-01
NL174549B (nl) 1984-02-01
HU176306B (en) 1981-01-28
JPS5625233B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1981-06-11
BE871771A (fr) 1979-05-03
CH643255A5 (en) 1984-05-30
ES474805A1 (es) 1980-01-16
GR81514B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-12-11
EG13594A (en) 1982-03-31
DD139850A5 (de) 1980-01-23
AR219562A1 (es) 1980-08-29
AR223015A1 (es) 1981-07-15
NO783705L (no) 1979-05-08
NL930062I2 (nl) 1993-11-16
YU40419B (en) 1985-12-31
SU816403A3 (ru) 1981-03-23
ES480121A0 (es) 1980-07-16
IT7829434A0 (it) 1978-11-03
SE7811382L (sv) 1979-05-06
NZ188813A (en) 1980-10-08
IE782179L (en) 1979-05-05
IT1100919B (it) 1985-09-28
PL210681A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-11-05
CS207671B2 (en) 1981-08-31
FI64366B (fi) 1983-07-29
NL930062I1 (nl) 1993-09-01
JPS5498792A (en) 1979-08-03
FR2407929A1 (fr) 1979-06-01
IL55857A0 (en) 1979-01-31
LU80470A1 (fr) 1980-06-05
DE2847623C2 (de) 1983-06-01
KE3350A (en) 1983-12-16
AU509329B2 (en) 1980-05-08
AU4132278A (en) 1979-05-17
YU38683A (en) 1983-06-30

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