PH22105A - Naphtalene derivatives and method of use thereof - Google Patents

Naphtalene derivatives and method of use thereof

Info

Publication number
PH22105A
PH22105A PH33266A PH33266A PH22105A PH 22105 A PH22105 A PH 22105A PH 33266 A PH33266 A PH 33266A PH 33266 A PH33266 A PH 33266A PH 22105 A PH22105 A PH 22105A
Authority
PH
Philippines
Prior art keywords
sup
formula
compounds
hydrogen atom
disclosed
Prior art date
Application number
PH33266A
Other languages
English (en)
Inventor
Tameo Iwasaki
Kohki Takashima
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of PH22105A publication Critical patent/PH22105A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Lubricants (AREA)
  • Fats And Perfumes (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
PH33266A 1985-01-10 1986-01-08 Naphtalene derivatives and method of use thereof PH22105A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP309085 1985-01-10

Publications (1)

Publication Number Publication Date
PH22105A true PH22105A (en) 1988-06-01

Family

ID=11547645

Family Applications (1)

Application Number Title Priority Date Filing Date
PH33266A PH22105A (en) 1985-01-10 1986-01-08 Naphtalene derivatives and method of use thereof

Country Status (18)

Country Link
US (2) US4771072A (ja)
EP (1) EP0188248B1 (ja)
JP (3) JPS61267541A (ja)
KR (1) KR890001884B1 (ja)
CN (1) CN1006464B (ja)
AT (1) ATE54441T1 (ja)
AU (1) AU584153B2 (ja)
BG (2) BG45385A3 (ja)
DD (1) DD270529A5 (ja)
DE (1) DE3672501D1 (ja)
ES (2) ES8705837A1 (ja)
FI (1) FI87557C (ja)
HU (1) HU196737B (ja)
IL (1) IL91117A0 (ja)
MY (1) MY101268A (ja)
NO (1) NO170760C (ja)
PH (1) PH22105A (ja)
PT (1) PT81814B (ja)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US5011948A (en) * 1985-04-12 1991-04-30 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
JPS6310746A (ja) * 1986-07-01 1988-01-18 Tanabe Seiyaku Co Ltd ナフタレン誘導体
AT388372B (de) * 1987-10-08 1989-06-12 Tanabe Seiyaku Co Neue naphthalinderivate und sie enthaltende pharmazeutika
JPH01135766A (ja) * 1987-11-20 1989-05-29 Tanabe Seiyaku Co Ltd ビフェニル誘導体
PH26342A (en) * 1988-11-29 1992-04-29 Univ Texas Microbial cellulose modified during synthesis
MY105057A (en) * 1989-01-27 1994-07-30 Tanabe Seiyaku Co A process for preparing naphthalene derivatives
US5003087A (en) * 1989-02-03 1991-03-26 Tanabe Seiyaku Co., Ltd. Process for preparing a naphthalene derivative and a synthetic intermediate thereof
EP0501578A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
EP0501579A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Naphthalene lactones as inhibitors of leukotriene biosynthesis
US5227399A (en) * 1991-02-28 1993-07-13 Merck Frosst Canada, Inc. Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
KR100252428B1 (ko) * 1991-10-17 2000-04-15 시오노 요시히코 리그난유사체,이의제조방법및이를함유한항지혈증제
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
CA2121060C (en) * 1993-04-16 2004-04-06 Sachio Mori Preparation of lignan analogues
ID18046A (id) * 1996-08-20 1998-02-19 Takeda Chemical Industries Ltd Senyawa siklik campuran, pembuatan dan penngunaannya.
AU5578099A (en) * 1998-08-25 2000-03-14 National Taiwan University Inhibition and treatment of hepatitis b virus and flavivirus by helioxanthin andits analogs
US6680344B1 (en) 1999-06-01 2004-01-20 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylmethane derivatives
JP2003500432A (ja) 1999-06-01 2003-01-07 ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター ジフェニルエーテル誘導体を用いて脱毛症を処置する方法
MXPA01012494A (es) 1999-06-01 2002-07-02 Univ Texas Southwestern Med Ct Metodo para tratar perdida capilar con el uso de compuestos sulfonil tiromimeticos.
SE0102168D0 (sv) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
HUP0401696A2 (hu) * 2001-08-28 2004-11-29 Sankyo Co., Ltd. Angiotenzin-II receptor antagonistát tartalmazó gyógyászati készítmény
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
EP2575821B1 (en) 2010-05-26 2015-08-12 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
EA029581B1 (ru) 2011-10-28 2018-04-30 ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи Применение ингибиторов рециркуляции желчных кислот для лечения холестатического заболевания печени или прурита
CN107375932B (zh) 2011-10-28 2021-12-21 夏尔人类遗传性治疗公司 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂
CA2907230A1 (en) 2013-03-15 2014-09-18 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
EP2968262A1 (en) 2013-03-15 2016-01-20 Lumena Pharmaceuticals, Inc. Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease
US20170119806A1 (en) * 2014-03-31 2017-05-04 Ohio State Innovation Foundation Arylnaphthalene lactone derivatives and methods of making and using thereof
US10682367B2 (en) 2016-02-26 2020-06-16 Ohio State Innovation Foundation Antitumor arylnaphthalene ligand glycosides
MX2021009622A (es) 2019-02-12 2021-11-04 Mirum Pharmaceuticals Inc Metodos para tratar la colestasis.

Also Published As

Publication number Publication date
PT81814A (en) 1986-02-01
JPH0272170A (ja) 1990-03-12
NO170760C (no) 1992-12-02
KR860005778A (ko) 1986-08-13
NO855355L (no) 1986-07-11
PT81814B (pt) 1988-07-29
NO170760B (no) 1992-08-24
JPH0272136A (ja) 1990-03-12
HU196737B (en) 1989-01-30
CN86100090A (zh) 1986-08-20
IL91117A0 (en) 1990-03-19
KR890001884B1 (ko) 1989-05-29
ES557052A0 (es) 1987-12-16
US4771072A (en) 1988-09-13
BG45385A3 (ja) 1989-05-15
CN1006464B (zh) 1990-01-17
JPS61267541A (ja) 1986-11-27
EP0188248A3 (en) 1986-12-17
ES8801239A1 (es) 1987-12-16
DD270529A5 (de) 1989-08-02
US5070103A (en) 1991-12-03
HUT42428A (en) 1987-07-28
AU5175185A (en) 1986-07-17
FI860089A (fi) 1986-07-11
JPH0549668B2 (ja) 1993-07-26
FI87557C (fi) 1993-01-25
BG45383A3 (ja) 1989-05-15
ES8705837A1 (es) 1987-05-16
AU584153B2 (en) 1989-05-18
ES550578A0 (es) 1987-05-16
ATE54441T1 (de) 1990-07-15
DE3672501D1 (de) 1990-08-16
MY101268A (en) 1991-08-17
FI860089A0 (fi) 1986-01-09
EP0188248B1 (en) 1990-07-11
FI87557B (fi) 1992-10-15
EP0188248A2 (en) 1986-07-23

Similar Documents

Publication Publication Date Title
PH22105A (en) Naphtalene derivatives and method of use thereof
DE3773546D1 (de) Naphthalenderivate, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen.
IL85988A (en) 1-phenyl-3-naphthalenyloxy-propanamines,process for their preparation and pharmaceutical compositions containing them
DE3170245D1 (en) Indane derivatives, methods of their preparation and compositions containing them
HUT45230A (en) Process for producing new phenoxy-acetic acid derivatives and pharmaceuticals comprising such compounds
GB1511463A (en) 1-acylamino methyl-1,2,3,4-tetrahydroisoquinolines
HUT70548A (en) Oxazolidone derivatives, process for producing them and pharmaceutical compositions containing them
ES8504682A1 (es) Un procedimiento para la preparacion de compuestos nitro alifaticos
CA2053477A1 (en) Heterocyclic amine derivatives, their production and use
EP0123962A3 (en) Novel benzimidazole derivative, process for the preparation thereof and pharmaceutical composition
ES8800140A1 (es) Un procedimiento para preparar un compuesto de n-fenil-trans-4-guanidincometilciclohexanocarboxamida.
DE3665309D1 (en) Novel peptides, compositions containing them and processes for their production
GR860045B (en) Novel piperazine derivatives processes for production thereof and pharmaceutical compositions comprising said compounds as active ingredient
EP0203795A3 (en) Benzo ûi,j¨ quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same
GB1242096A (en) Benzobenzofuranooxepine compounds and process for preparing the same
JPS5695188A (en) Theophyllin derivative and its production
EP0035853A3 (en) Thienocycloheptapyrrole derivatives, process for their preparation and pharmaceutical compositions containing them
ES8700651A1 (es) Un procedimiento para preparar un compuesto relacionado con arfamenina
FR2379505A1 (fr) Nouveaux produits doues notamment de proprietes therapeutiques, leurs procedes de preparation, et medicaments a base de ces produits