FI860089A - Naftalinderivat och foerfarande foer deras framstaellning. - Google Patents

Naftalinderivat och foerfarande foer deras framstaellning. Download PDF

Info

Publication number
FI860089A
FI860089A FI860089A FI860089A FI860089A FI 860089 A FI860089 A FI 860089A FI 860089 A FI860089 A FI 860089A FI 860089 A FI860089 A FI 860089A FI 860089 A FI860089 A FI 860089A
Authority
FI
Finland
Prior art keywords
sup
formula
fuerfarande
compounds
oil
Prior art date
Application number
FI860089A
Other languages
English (en)
Other versions
FI87557C (fi
FI87557B (fi
FI860089A0 (fi
Inventor
Tameo Iwasaki
Kohki Takashimna
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of FI860089A0 publication Critical patent/FI860089A0/fi
Publication of FI860089A publication Critical patent/FI860089A/fi
Application granted granted Critical
Publication of FI87557B publication Critical patent/FI87557B/fi
Publication of FI87557C publication Critical patent/FI87557C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92—Naphthofurans; Hydrogenated naphthofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/337—Polycyclic acids with carboxyl groups bound to condensed ring systems
    • C07C63/34—Polycyclic acids with carboxyl groups bound to condensed ring systems containing two condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Lubricants (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
FI860089A 1985-01-10 1986-01-09 Foerfarande foer framstaellning av farmakologiskt vaerdefullt naftalenderivat FI87557C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP309085 1985-01-10
JP309085 1985-01-10

Publications (4)

Publication Number Publication Date
FI860089A0 FI860089A0 (fi) 1986-01-09
FI860089A true FI860089A (fi) 1986-07-11
FI87557B FI87557B (fi) 1992-10-15
FI87557C FI87557C (fi) 1993-01-25

Family

ID=11547645

Family Applications (1)

Application Number Title Priority Date Filing Date
FI860089A FI87557C (fi) 1985-01-10 1986-01-09 Foerfarande foer framstaellning av farmakologiskt vaerdefullt naftalenderivat

Country Status (18)

Country Link
US (2) US4771072A (fi)
EP (1) EP0188248B1 (fi)
JP (3) JPS61267541A (fi)
KR (1) KR890001884B1 (fi)
CN (1) CN1006464B (fi)
AT (1) ATE54441T1 (fi)
AU (1) AU584153B2 (fi)
BG (2) BG45383A3 (fi)
DD (1) DD270529A5 (fi)
DE (1) DE3672501D1 (fi)
ES (2) ES8705837A1 (fi)
FI (1) FI87557C (fi)
HU (1) HU196737B (fi)
IL (1) IL91117A0 (fi)
MY (1) MY101268A (fi)
NO (1) NO170760C (fi)
PH (1) PH22105A (fi)
PT (1) PT81814B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US5011948A (en) * 1985-04-12 1991-04-30 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
JPS6310746A (ja) * 1986-07-01 1988-01-18 Tanabe Seiyaku Co Ltd ナフタレン誘導体
AT388372B (de) * 1987-10-08 1989-06-12 Tanabe Seiyaku Co Neue naphthalinderivate und sie enthaltende pharmazeutika
JPH01135766A (ja) * 1987-11-20 1989-05-29 Tanabe Seiyaku Co Ltd ビフェニル誘導体
PH26342A (en) * 1988-11-29 1992-04-29 Univ Texas Microbial cellulose modified during synthesis
MY105057A (en) * 1989-01-27 1994-07-30 Tanabe Seiyaku Co A process for preparing naphthalene derivatives
ZA9076B (en) * 1989-02-03 1990-10-31 Tanabe Seiyaku Co Limited A process for preparing a naphthalene derivative and a synthetic intermediate thereof
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
EP0501579A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Naphthalene lactones as inhibitors of leukotriene biosynthesis
EP0501578A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
US5227399A (en) * 1991-02-28 1993-07-13 Merck Frosst Canada, Inc. Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
DE69211994T2 (de) * 1991-10-17 1997-02-20 Shionogi & Co Lignan-analoge, ihre herstellung und hypolipidemische arzneimittel
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
CA2121060C (en) * 1993-04-16 2004-04-06 Sachio Mori Preparation of lignan analogues
ID18046A (id) * 1996-08-20 1998-02-19 Takeda Chemical Industries Ltd Senyawa siklik campuran, pembuatan dan penngunaannya.
CA2341540A1 (en) * 1998-08-25 2000-03-02 Yale University Inhibition and treatment of hepatitis b virus and flavivirus by helioxanthin and its analogs
CA2374263A1 (en) 1999-06-01 2000-12-07 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylether derivatives
AU3712100A (en) 1999-06-01 2000-12-18 University Of Texas Southwestern Medical Center, The Method of treating hair loss using sulfonyl thyromimetic compounds
US6680344B1 (en) 1999-06-01 2004-01-20 The University Of Texas Southwestern Medical Center Method of treating hair loss using diphenylmethane derivatives
SE0102168D0 (sv) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
WO2003020315A1 (fr) * 2001-08-28 2003-03-13 Sankyo Company, Limited Compositions medicinales contenant un antagoniste du recepteur d'angiotensine ii
GB0307918D0 (en) 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
US20110294767A1 (en) 2010-05-26 2011-12-01 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
CN104023727B (zh) 2011-10-28 2017-04-05 鲁美纳医药公司 用于治疗小儿胆汁淤积性肝病的胆汁酸再循环抑制剂
US20130108573A1 (en) 2011-10-28 2013-05-02 Lumena Pharmaceuticals, Inc. Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease
KR20230152818A (ko) 2013-03-15 2023-11-03 샤이어 휴먼 지네틱 테라피즈 인크. 원발성 담관염 및 염증성 장 질환 치료용 담즙산 재순환 억제제
AU2014229050A1 (en) 2013-03-15 2015-10-22 Lumena Pharmaceuticals Llc Bile acid recycling inhibitors for treatment of Barrett's esophagus and gastroesophageal reflux disease
US20170119806A1 (en) * 2014-03-31 2017-05-04 Ohio State Innovation Foundation Arylnaphthalene lactone derivatives and methods of making and using thereof
WO2017147624A1 (en) 2016-02-26 2017-08-31 Ohio State Innovation Foundation Antitumor arylnaphthalene ligand glycosides
EP3923943B1 (en) 2019-02-12 2024-07-31 Mirum Pharmaceuticals, Inc. Genotype and dose-dependent response to an asbti in patients with bile salt export pump deficiency

Also Published As

Publication number Publication date
KR890001884B1 (ko) 1989-05-29
NO170760C (no) 1992-12-02
EP0188248B1 (en) 1990-07-11
PT81814A (en) 1986-02-01
CN86100090A (zh) 1986-08-20
AU584153B2 (en) 1989-05-18
ATE54441T1 (de) 1990-07-15
ES550578A0 (es) 1987-05-16
PH22105A (en) 1988-06-01
HU196737B (en) 1989-01-30
US4771072A (en) 1988-09-13
MY101268A (en) 1991-08-17
JPS61267541A (ja) 1986-11-27
FI87557C (fi) 1993-01-25
BG45383A3 (bg) 1989-05-15
DE3672501D1 (de) 1990-08-16
ES557052A0 (es) 1987-12-16
ES8705837A1 (es) 1987-05-16
NO855355L (no) 1986-07-11
HUT42428A (en) 1987-07-28
EP0188248A2 (en) 1986-07-23
KR860005778A (ko) 1986-08-13
ES8801239A1 (es) 1987-12-16
PT81814B (pt) 1988-07-29
CN1006464B (zh) 1990-01-17
FI87557B (fi) 1992-10-15
BG45385A3 (bg) 1989-05-15
US5070103A (en) 1991-12-03
NO170760B (no) 1992-08-24
JPH0272170A (ja) 1990-03-12
JPH0549668B2 (fi) 1993-07-26
EP0188248A3 (en) 1986-12-17
IL91117A0 (en) 1990-03-19
JPH0272136A (ja) 1990-03-12
FI860089A0 (fi) 1986-01-09
DD270529A5 (de) 1989-08-02
AU5175185A (en) 1986-07-17

Similar Documents

Publication Publication Date Title
FI860089A0 (fi) Naftalinderivat och foerfarande foer deras framstaellning.
DE3773546D1 (de) Naphthalenderivate, ihr herstellungsverfahren und diese enthaltende pharmazeutische zusammensetzungen.
IL85988A (en) 1-phenyl-3-naphthalenyloxy-propanamines,process for their preparation and pharmaceutical compositions containing them
DE3170245D1 (en) Indane derivatives, methods of their preparation and compositions containing them
HUT68721A (en) Benzofuran and benzizoxazole derivatives, pharmaceutical composition containing said compounds as active agent and process for preparing them
DE69004340D1 (de) Substituierte 2-Alkinylphenole mit entzündungshemmender Wirkung, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen.
MX9301240A (es) Derivados heterociclicos de cetona, condensados, metodo para su produccion y composicion farmaceutica que los contiene.
HUT45230A (en) Process for producing new phenoxy-acetic acid derivatives and pharmaceuticals comprising such compounds
HUT70548A (en) Oxazolidone derivatives, process for producing them and pharmaceutical compositions containing them
CA2053477A1 (en) Heterocyclic amine derivatives, their production and use
ATE48994T1 (de) Benzimidazol-derivat, verfahren zu seiner herstellung und pharmazeutische zusammensetzung.
EP0316939A3 (en) Biphenyl derivatives, preparation method, pharmaceutical compositions comprising them and use
GR860045B (en) Novel piperazine derivatives processes for production thereof and pharmaceutical compositions comprising said compounds as active ingredient
EP0203795A3 (en) Benzo ûi,j¨ quinolizine-2-carboxylic acid derivatives, the salts and their hydrates, pharmaceutical compositions thereof, and process for preparing the same
FR2412562A1 (fr) Nouveaux derives de 6'-epi-fortimicines a et b utiles notamment comme agents antibacteriens, procede et intermediaires pour leur preparation et composition pharmaceutique les contenant
ES374762A1 (es) Procedimiento para la preparacion de derivado de benzo (b) benzofurano (2,3-e) oxapina.
JPS5695188A (en) Theophyllin derivative and its production
ES2059572T3 (es) Derivado del antibiotico a 42867.
FR2379505A1 (fr) Nouveaux produits doues notamment de proprietes therapeutiques, leurs procedes de preparation, et medicaments a base de ces produits
EP0035853A3 (en) Thienocycloheptapyrrole derivatives, process for their preparation and pharmaceutical compositions containing them
RU94031211A (ru) Производные изатина, способ их получения и фармацевтическая композиция на их основе
JO1672B1 (en) Dialoxy-pyridinyl-benzimidazole derivatives and a way to prepare and use it in a pharmacy

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: TANABE SEIYAKU CO., . LTD.