PH16714A - N-methylene derivatives of thienamycin - Google Patents

N-methylene derivatives of thienamycin

Info

Publication number
PH16714A
PH16714A PH19142A PH19142A PH16714A PH 16714 A PH16714 A PH 16714A PH 19142 A PH19142 A PH 19142A PH 19142 A PH19142 A PH 19142A PH 16714 A PH16714 A PH 16714A
Authority
PH
Philippines
Prior art keywords
thienamycin
methylene derivatives
methylene
derivatives
Prior art date
Application number
PH19142A
Other languages
English (en)
Inventor
Grant Christensen Burton
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PH16714A publication Critical patent/PH16714A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PH19142A 1975-11-21 1976-11-18 N-methylene derivatives of thienamycin PH16714A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (1)

Publication Number Publication Date
PH16714A true PH16714A (en) 1984-01-25

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
PH19142A PH16714A (en) 1975-11-21 1976-11-18 N-methylene derivatives of thienamycin

Country Status (27)

Country Link
AT (1) AT358168B (https=)
AU (1) AU512383B2 (https=)
BG (1) BG34037A3 (https=)
CA (1) CA1083577A (https=)
CH (2) CH632510A5 (https=)
DD (1) DD127742A5 (https=)
DE (1) DE2652679A1 (https=)
DK (1) DK157401C (https=)
EG (1) EG12261A (https=)
ES (1) ES453501A1 (https=)
FI (1) FI62306C (https=)
FR (1) FR2332012A1 (https=)
GB (1) GB1570990A (https=)
GR (1) GR62072B (https=)
HK (1) HK29683A (https=)
HU (1) HU180865B (https=)
IE (1) IE44433B1 (https=)
IL (1) IL50911A (https=)
KE (1) KE3286A (https=)
NL (1) NL189297C (https=)
NO (1) NO153298C (https=)
NZ (1) NZ182630A (https=)
PH (1) PH16714A (https=)
PL (1) PL110937B1 (https=)
PT (1) PT65865B (https=)
SE (1) SE427841B (https=)
SG (1) SG10983G (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK170778A (da) * 1977-05-05 1979-01-15 Merck & Co Inc Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
EP0551330A4 (en) * 1990-08-30 1994-07-06 Oregon State Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
DE2652679A1 (de) 1977-06-02
PT65865A (en) 1976-12-01
AU512383B2 (en) 1980-10-09
BG34037A3 (bg) 1983-06-15
HU180865B (en) 1983-04-29
FI763308A7 (https=) 1977-05-22
FI62306C (fi) 1982-12-10
CA1083577A (en) 1980-08-12
SG10983G (en) 1983-12-16
NO153298C (no) 1986-02-19
NL189297C (nl) 1993-03-01
NL7612939A (nl) 1977-05-24
GR62072B (en) 1979-02-20
HK29683A (en) 1983-08-26
DK157401B (da) 1990-01-02
NL189297B (nl) 1992-10-01
EG12261A (en) 1978-12-31
PT65865B (en) 1978-10-12
KE3286A (en) 1983-06-17
IL50911A0 (en) 1977-01-31
NO763958L (https=) 1977-05-24
IE44433L (en) 1977-05-21
PL193809A1 (pl) 1978-01-16
AT358168B (de) 1980-08-25
AU1964776A (en) 1978-05-25
PL110937B1 (en) 1980-08-30
ATA863476A (de) 1980-01-15
IE44433B1 (en) 1981-12-02
FR2332012A1 (fr) 1977-06-17
GB1570990A (en) 1980-07-09
DE2652679C2 (https=) 1990-03-01
SE427841B (sv) 1983-05-09
NZ182630A (en) 1979-07-11
NO153298B (no) 1985-11-11
IL50911A (en) 1981-01-30
FI62306B (fi) 1982-08-31
DD127742A5 (de) 1977-10-12
SE7612963L (sv) 1977-05-22
FR2332012B1 (https=) 1978-11-17
CH632510A5 (en) 1982-10-15
CH633800A5 (en) 1982-12-31
ES453501A1 (es) 1978-03-01
DK523576A (da) 1977-05-22
DK157401C (da) 1990-05-21

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