JPS5277085A - Nnalkyl derivative of thienamycine - Google Patents

Nnalkyl derivative of thienamycine

Info

Publication number
JPS5277085A
JPS5277085A JP51139653A JP13965376A JPS5277085A JP S5277085 A JPS5277085 A JP S5277085A JP 51139653 A JP51139653 A JP 51139653A JP 13965376 A JP13965376 A JP 13965376A JP S5277085 A JPS5277085 A JP S5277085A
Authority
JP
Japan
Prior art keywords
thienamycine
nnalkyl
derivative
nnalkyl derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP51139653A
Other languages
Japanese (ja)
Inventor
Jii Kurisutensen Baaton
Ee Fuaiaasutoon Reimondo
Jiee Reenza Uiriamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5277085A publication Critical patent/JPS5277085A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP51139653A 1975-11-21 1976-11-22 Nnalkyl derivative of thienamycine Pending JPS5277085A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429775A 1975-11-21 1975-11-21

Publications (1)

Publication Number Publication Date
JPS5277085A true JPS5277085A (en) 1977-06-29

Family

ID=24543224

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51139653A Pending JPS5277085A (en) 1975-11-21 1976-11-22 Nnalkyl derivative of thienamycine

Country Status (8)

Country Link
JP (1) JPS5277085A (en)
CH (1) CH628051A5 (en)
DE (1) DE2652676A1 (en)
DK (1) DK523676A (en)
FR (1) FR2332014A1 (en)
GB (1) GB1570988A (en)
NL (1) NL7612937A (en)
SE (1) SE7612964L (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS565478A (en) * 1979-04-19 1981-01-20 Merck & Co Inc 22substitutedd66substituteddcarbadethiapenee 22emm33carboxylic acid
JPS56131565A (en) * 1980-02-28 1981-10-15 Fujisawa Pharmaceut Co Ltd 4-substituted-2-oxoazetidine compound and its preparation
JPS5798257A (en) * 1980-12-10 1982-06-18 Sankyo Co Ltd 3,4-disubstituted azetidine-2-one compound and its preparation
JPS5910588A (en) * 1982-06-18 1984-01-20 ブリストル―マイヤーズ スクイブ カンパニー Carbapenem antibiotic

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU531084B2 (en) * 1977-10-19 1983-08-11 Merck & Co., Inc. Azetidine derivatives
AU4061378A (en) * 1977-10-19 1980-04-17 Merck & Co., Inc. 1-azabicyclo (3.2.0) hept-2-enes
EP0008888B1 (en) * 1978-08-23 1983-09-21 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
EP0062407A1 (en) * 1981-03-10 1982-10-13 Beecham Group Plc Therapeutic compounds containing beta-lactams
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
WO2005056553A1 (en) * 2003-12-09 2005-06-23 Choongwae Pharm.Co. A new process for preparation of imipenem

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS565478A (en) * 1979-04-19 1981-01-20 Merck & Co Inc 22substitutedd66substituteddcarbadethiapenee 22emm33carboxylic acid
JPS56131565A (en) * 1980-02-28 1981-10-15 Fujisawa Pharmaceut Co Ltd 4-substituted-2-oxoazetidine compound and its preparation
JPH023781B2 (en) * 1980-02-28 1990-01-24 Fujisawa Pharmaceutical Co
JPS5798257A (en) * 1980-12-10 1982-06-18 Sankyo Co Ltd 3,4-disubstituted azetidine-2-one compound and its preparation
JPS5910588A (en) * 1982-06-18 1984-01-20 ブリストル―マイヤーズ スクイブ カンパニー Carbapenem antibiotic

Also Published As

Publication number Publication date
DK523676A (en) 1977-05-22
SE7612964L (en) 1977-05-22
DE2652676A1 (en) 1977-06-02
FR2332014A1 (en) 1977-06-17
NL7612937A (en) 1977-05-24
FR2332014B1 (en) 1978-11-10
GB1570988A (en) 1980-07-09
CH628051A5 (en) 1982-02-15

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