JPS5277083A - Nnacyl derivatives of thienamycine - Google Patents

Nnacyl derivatives of thienamycine

Info

Publication number
JPS5277083A
JPS5277083A JP51139650A JP13965076A JPS5277083A JP S5277083 A JPS5277083 A JP S5277083A JP 51139650 A JP51139650 A JP 51139650A JP 13965076 A JP13965076 A JP 13965076A JP S5277083 A JPS5277083 A JP S5277083A
Authority
JP
Japan
Prior art keywords
thienamycine
nnacyl
derivatives
nnacyl derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP51139650A
Other languages
Japanese (ja)
Other versions
JPS61346B2 (en
Inventor
Barashiyu Ruisu
Jii Kurisutensen Baaton
Hannaa Jiyon
Jiee Reenza Uiriamu
Etsuchi Shiii Debitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5277083A publication Critical patent/JPS5277083A/en
Publication of JPS61346B2 publication Critical patent/JPS61346B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
JP51139650A 1975-11-21 1976-11-22 Nnacyl derivatives of thienamycine Granted JPS5277083A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429175A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
JPS5277083A true JPS5277083A (en) 1977-06-29
JPS61346B2 JPS61346B2 (en) 1986-01-08

Family

ID=24543192

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51139650A Granted JPS5277083A (en) 1975-11-21 1976-11-22 Nnacyl derivatives of thienamycine

Country Status (8)

Country Link
JP (1) JPS5277083A (en)
CH (1) CH632509A5 (en)
DE (1) DE2652675A1 (en)
DK (1) DK523276A (en)
FR (1) FR2332016A1 (en)
GB (1) GB1570986A (en)
NL (1) NL189298C (en)
SE (1) SE427840B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2966187D1 (en) * 1978-08-23 1983-10-27 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
US4387051A (en) * 1979-10-29 1983-06-07 Beecham Group Limited β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions
EP0044142A1 (en) * 1980-07-03 1982-01-20 Beecham Group Plc Process for the preparation of beta-lactam antibiotics
WO2017132321A1 (en) * 2016-01-29 2017-08-03 The Johns Hopkins University Novel inhibitors of bacterial growth

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348984A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production

Also Published As

Publication number Publication date
NL189298B (en) 1992-10-01
NL7612940A (en) 1977-05-24
NL189298C (en) 1993-03-01
FR2332016B1 (en) 1978-11-10
SE427840B (en) 1983-05-09
FR2332016A1 (en) 1977-06-17
DK523276A (en) 1977-05-22
CH632509A5 (en) 1982-10-15
SE7612960L (en) 1977-05-22
DE2652675C2 (en) 1990-02-01
JPS61346B2 (en) 1986-01-08
GB1570986A (en) 1980-07-09
DE2652675A1 (en) 1977-06-02

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