PL193809A1 - Sposob wytwarzania n-metylenowych pochodnych tienamycyny - Google Patents

Sposob wytwarzania n-metylenowych pochodnych tienamycyny

Info

Publication number
PL193809A1
PL193809A1 PL19380976A PL19380976A PL193809A1 PL 193809 A1 PL193809 A1 PL 193809A1 PL 19380976 A PL19380976 A PL 19380976A PL 19380976 A PL19380976 A PL 19380976A PL 193809 A1 PL193809 A1 PL 193809A1
Authority
PL
Poland
Prior art keywords
thienamycin
production
methylene derivatives
methylene
derivatives
Prior art date
Application number
PL19380976A
Other languages
English (en)
Other versions
PL110937B1 (en
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PL193809A1 publication Critical patent/PL193809A1/pl
Publication of PL110937B1 publication Critical patent/PL110937B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL1976193809A 1975-11-21 1976-11-20 Process for the preparation of novel n-methylene derivatives of thienamycin PL110937B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (2)

Publication Number Publication Date
PL193809A1 true PL193809A1 (pl) 1978-01-16
PL110937B1 PL110937B1 (en) 1980-08-30

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1976193809A PL110937B1 (en) 1975-11-21 1976-11-20 Process for the preparation of novel n-methylene derivatives of thienamycin

Country Status (27)

Country Link
AT (1) AT358168B (pl)
AU (1) AU512383B2 (pl)
BG (1) BG34037A3 (pl)
CA (1) CA1083577A (pl)
CH (2) CH632510A5 (pl)
DD (1) DD127742A5 (pl)
DE (1) DE2652679A1 (pl)
DK (1) DK157401C (pl)
EG (1) EG12261A (pl)
ES (1) ES453501A1 (pl)
FI (1) FI62306C (pl)
FR (1) FR2332012A1 (pl)
GB (1) GB1570990A (pl)
GR (1) GR62072B (pl)
HK (1) HK29683A (pl)
HU (1) HU180865B (pl)
IE (1) IE44433B1 (pl)
IL (1) IL50911A (pl)
KE (1) KE3286A (pl)
NL (1) NL189297C (pl)
NO (1) NO153298C (pl)
NZ (1) NZ182630A (pl)
PH (1) PH16714A (pl)
PL (1) PL110937B1 (pl)
PT (1) PT65865B (pl)
SE (1) SE427841B (pl)
SG (1) SG10983G (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
SE436569B (sv) * 1977-05-05 1985-01-07 Merck & Co Inc Analogiforfarande for framstellning av tienamycinderivat
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
AU671071B2 (en) * 1990-08-30 1996-08-15 State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University, Portland, Oregon, and The University of Oregon, Eugene, Oregon, Johnson Hall, Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
IE44433L (en) 1977-05-21
GB1570990A (en) 1980-07-09
DE2652679C2 (pl) 1990-03-01
ATA863476A (de) 1980-01-15
BG34037A3 (en) 1983-06-15
FI62306B (fi) 1982-08-31
FR2332012A1 (fr) 1977-06-17
PT65865A (en) 1976-12-01
HU180865B (en) 1983-04-29
HK29683A (en) 1983-08-26
CA1083577A (en) 1980-08-12
CH633800A5 (en) 1982-12-31
EG12261A (en) 1978-12-31
KE3286A (en) 1983-06-17
SE7612963L (sv) 1977-05-22
PH16714A (en) 1984-01-25
NO763958L (pl) 1977-05-24
DK157401B (da) 1990-01-02
IE44433B1 (en) 1981-12-02
DK523576A (da) 1977-05-22
SE427841B (sv) 1983-05-09
FI62306C (fi) 1982-12-10
NL189297C (nl) 1993-03-01
DD127742A5 (de) 1977-10-12
GR62072B (en) 1979-02-20
NL189297B (nl) 1992-10-01
PT65865B (en) 1978-10-12
IL50911A (en) 1981-01-30
AT358168B (de) 1980-08-25
CH632510A5 (en) 1982-10-15
NL7612939A (nl) 1977-05-24
NO153298C (no) 1986-02-19
AU1964776A (en) 1978-05-25
AU512383B2 (en) 1980-10-09
FI763308A (pl) 1977-05-22
FR2332012B1 (pl) 1978-11-17
SG10983G (en) 1983-12-16
IL50911A0 (en) 1977-01-31
ES453501A1 (es) 1978-03-01
NO153298B (no) 1985-11-11
DK157401C (da) 1990-05-21
DE2652679A1 (de) 1977-06-02
PL110937B1 (en) 1980-08-30
NZ182630A (en) 1979-07-11

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20070417