PH16714A - N-methylene derivatives of thienamycin - Google Patents

N-methylene derivatives of thienamycin

Info

Publication number
PH16714A
PH16714A PH19142A PH19142A PH16714A PH 16714 A PH16714 A PH 16714A PH 19142 A PH19142 A PH 19142A PH 19142 A PH19142 A PH 19142A PH 16714 A PH16714 A PH 16714A
Authority
PH
Philippines
Prior art keywords
thienamycin
methylene derivatives
methylene
derivatives
Prior art date
Application number
PH19142A
Inventor
Grant Christensen Burton
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PH16714A publication Critical patent/PH16714A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
PH19142A 1975-11-21 1976-11-18 N-methylene derivatives of thienamycin PH16714A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (1)

Publication Number Publication Date
PH16714A true PH16714A (en) 1984-01-25

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
PH19142A PH16714A (en) 1975-11-21 1976-11-18 N-methylene derivatives of thienamycin

Country Status (27)

Country Link
AT (1) AT358168B (en)
AU (1) AU512383B2 (en)
BG (1) BG34037A3 (en)
CA (1) CA1083577A (en)
CH (2) CH632510A5 (en)
DD (1) DD127742A5 (en)
DE (1) DE2652679A1 (en)
DK (1) DK157401C (en)
EG (1) EG12261A (en)
ES (1) ES453501A1 (en)
FI (1) FI62306C (en)
FR (1) FR2332012A1 (en)
GB (1) GB1570990A (en)
GR (1) GR62072B (en)
HK (1) HK29683A (en)
HU (1) HU180865B (en)
IE (1) IE44433B1 (en)
IL (1) IL50911A (en)
KE (1) KE3286A (en)
NL (1) NL189297C (en)
NO (1) NO153298C (en)
NZ (1) NZ182630A (en)
PH (1) PH16714A (en)
PL (1) PL110937B1 (en)
PT (1) PT65865B (en)
SE (1) SE427841B (en)
SG (1) SG10983G (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
SE436569B (en) * 1977-05-05 1985-01-07 Merck & Co Inc ANALOGY PROCEDURE FOR THE PREPARATION OF TIENAMYCIN DERIVATIVES
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (en) * 1978-07-03 1988-11-28 Merck & Co Inc ANALOGY PROCEDURE FOR THE PREPARATION OF CRYSTALLINIC N-FORMIMIDOYL-THIENAMYCINE MONOHYDRATE
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
JPH06501002A (en) * 1990-08-30 1994-01-27 オレゴン州 Substituted amidines with high binding properties to sigma receptors and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348984A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
NL7612939A (en) 1977-05-24
ES453501A1 (en) 1978-03-01
ATA863476A (en) 1980-01-15
NL189297B (en) 1992-10-01
HK29683A (en) 1983-08-26
IE44433L (en) 1977-05-21
DE2652679A1 (en) 1977-06-02
NL189297C (en) 1993-03-01
SE7612963L (en) 1977-05-22
CH632510A5 (en) 1982-10-15
FR2332012B1 (en) 1978-11-17
DE2652679C2 (en) 1990-03-01
AU1964776A (en) 1978-05-25
SG10983G (en) 1983-12-16
GR62072B (en) 1979-02-20
AT358168B (en) 1980-08-25
HU180865B (en) 1983-04-29
PT65865B (en) 1978-10-12
PL193809A1 (en) 1978-01-16
KE3286A (en) 1983-06-17
GB1570990A (en) 1980-07-09
FI763308A (en) 1977-05-22
NZ182630A (en) 1979-07-11
NO763958L (en) 1977-05-24
CH633800A5 (en) 1982-12-31
CA1083577A (en) 1980-08-12
IL50911A0 (en) 1977-01-31
FI62306B (en) 1982-08-31
PT65865A (en) 1976-12-01
PL110937B1 (en) 1980-08-30
EG12261A (en) 1978-12-31
DD127742A5 (en) 1977-10-12
AU512383B2 (en) 1980-10-09
SE427841B (en) 1983-05-09
DK157401B (en) 1990-01-02
NO153298B (en) 1985-11-11
IE44433B1 (en) 1981-12-02
DK523576A (en) 1977-05-22
FR2332012A1 (en) 1977-06-17
DK157401C (en) 1990-05-21
NO153298C (en) 1986-02-19
FI62306C (en) 1982-12-10
BG34037A3 (en) 1983-06-15
IL50911A (en) 1981-01-30

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