AU512383B2 - Thinenamycin derivatives - Google Patents

Thinenamycin derivatives

Info

Publication number
AU512383B2
AU512383B2 AU19647/76A AU1964776A AU512383B2 AU 512383 B2 AU512383 B2 AU 512383B2 AU 19647/76 A AU19647/76 A AU 19647/76A AU 1964776 A AU1964776 A AU 1964776A AU 512383 B2 AU512383 B2 AU 512383B2
Authority
AU
Australia
Prior art keywords
thinenamycin
derivatives
thinenamycin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU19647/76A
Other versions
AU1964776A (en
Inventor
B. G. Leanza W. J. and Wildoner K. J Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of AU1964776A publication Critical patent/AU1964776A/en
Application granted granted Critical
Publication of AU512383B2 publication Critical patent/AU512383B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU19647/76A 1975-11-21 1976-11-15 Thinenamycin derivatives Expired AU512383B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
USUS634,296 1975-11-21
US67626176A 1976-04-12 1976-04-12
USUS676,261 1976-04-12
US73365476A 1976-10-18 1976-10-18
USUS733,654 1976-10-18

Publications (2)

Publication Number Publication Date
AU1964776A AU1964776A (en) 1978-05-25
AU512383B2 true AU512383B2 (en) 1980-10-09

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
AU19647/76A Expired AU512383B2 (en) 1975-11-21 1976-11-15 Thinenamycin derivatives

Country Status (27)

Country Link
AT (1) AT358168B (en)
AU (1) AU512383B2 (en)
BG (1) BG34037A3 (en)
CA (1) CA1083577A (en)
CH (2) CH632510A5 (en)
DD (1) DD127742A5 (en)
DE (1) DE2652679A1 (en)
DK (1) DK157401C (en)
EG (1) EG12261A (en)
ES (1) ES453501A1 (en)
FI (1) FI62306C (en)
FR (1) FR2332012A1 (en)
GB (1) GB1570990A (en)
GR (1) GR62072B (en)
HK (1) HK29683A (en)
HU (1) HU180865B (en)
IE (1) IE44433B1 (en)
IL (1) IL50911A (en)
KE (1) KE3286A (en)
NL (1) NL189297C (en)
NO (1) NO153298C (en)
NZ (1) NZ182630A (en)
PH (1) PH16714A (en)
PL (1) PL110937B1 (en)
PT (1) PT65865B (en)
SE (1) SE427841B (en)
SG (1) SG10983G (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK170778A (en) * 1977-05-05 1979-01-15 Merck & Co Inc PROCEDURE FOR MAKING N-ALKYL-N-IMINOMETHYL DERIVATIVES OF THIENAMYCIN
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (en) * 1978-07-03 1988-11-28 Merck & Co Inc ANALOGY PROCEDURE FOR THE PREPARATION OF CRYSTALLINIC N-FORMIMIDOYL-THIENAMYCINE MONOHYDRATE
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
CA2089261A1 (en) * 1990-08-30 1992-03-01 John F.W. Keana Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
FI62306B (en) 1982-08-31
IL50911A (en) 1981-01-30
GR62072B (en) 1979-02-20
IE44433L (en) 1977-05-21
HU180865B (en) 1983-04-29
FR2332012B1 (en) 1978-11-17
AU1964776A (en) 1978-05-25
KE3286A (en) 1983-06-17
DE2652679A1 (en) 1977-06-02
NO153298B (en) 1985-11-11
PT65865B (en) 1978-10-12
DD127742A5 (en) 1977-10-12
NZ182630A (en) 1979-07-11
GB1570990A (en) 1980-07-09
SE7612963L (en) 1977-05-22
DK157401C (en) 1990-05-21
DK523576A (en) 1977-05-22
SG10983G (en) 1983-12-16
AT358168B (en) 1980-08-25
PL110937B1 (en) 1980-08-30
DE2652679C2 (en) 1990-03-01
BG34037A3 (en) 1983-06-15
FI62306C (en) 1982-12-10
NO763958L (en) 1977-05-24
PL193809A1 (en) 1978-01-16
EG12261A (en) 1978-12-31
DK157401B (en) 1990-01-02
FI763308A (en) 1977-05-22
HK29683A (en) 1983-08-26
IE44433B1 (en) 1981-12-02
NL189297B (en) 1992-10-01
NL189297C (en) 1993-03-01
NO153298C (en) 1986-02-19
PH16714A (en) 1984-01-25
CA1083577A (en) 1980-08-12
CH633800A5 (en) 1982-12-31
SE427841B (en) 1983-05-09
ATA863476A (en) 1980-01-15
IL50911A0 (en) 1977-01-31
FR2332012A1 (en) 1977-06-17
NL7612939A (en) 1977-05-24
ES453501A1 (en) 1978-03-01
CH632510A5 (en) 1982-10-15
PT65865A (en) 1976-12-01

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