DK554179A - Fremgangsmaade til fremstilling af ergolinderivater - Google Patents

Fremgangsmaade til fremstilling af ergolinderivater

Info

Publication number
DK554179A
DK554179A DK554179A DK554179A DK554179A DK 554179 A DK554179 A DK 554179A DK 554179 A DK554179 A DK 554179A DK 554179 A DK554179 A DK 554179A DK 554179 A DK554179 A DK 554179A
Authority
DK
Denmark
Prior art keywords
procedure
production
ergolin
derivatives
ergolin derivatives
Prior art date
Application number
DK554179A
Other languages
English (en)
Inventor
P Stuetz
T Fehr
P Stadler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH1668075A external-priority patent/CH620441A5/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK554179A publication Critical patent/DK554179A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06Lysergic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12Nitrogen atoms
DK554179A 1975-12-23 1979-12-21 Fremgangsmaade til fremstilling af ergolinderivater DK554179A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1668075A CH620441A5 (en) 1975-12-23 1975-12-23 Process for the preparation of novel ergoline compounds
CH618876 1976-05-18

Publications (1)

Publication Number Publication Date
DK554179A true DK554179A (da) 1979-12-21

Family

ID=25699142

Family Applications (2)

Application Number Title Priority Date Filing Date
DK562376A DK146205C (da) 1975-12-23 1976-12-14 Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater
DK554179A DK554179A (da) 1975-12-23 1979-12-21 Fremgangsmaade til fremstilling af ergolinderivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK562376A DK146205C (da) 1975-12-23 1976-12-14 Analogifremgangsmaade til fremstilling af 8alfa-ergolin-i-derivater

Country Status (20)

Country Link
US (1) US4348391A (da)
JP (1) JPS5278900A (da)
AU (1) AU514288B2 (da)
CA (1) CA1092100A (da)
DE (1) DE2656344A1 (da)
DK (2) DK146205C (da)
ES (1) ES454442A1 (da)
FI (1) FI763587A (da)
FR (1) FR2336135A1 (da)
GB (1) GB1567484A (da)
HK (1) HK3483A (da)
IE (1) IE44242B1 (da)
IL (1) IL51133A (da)
MY (1) MY8400060A (da)
NL (1) NL7614018A (da)
NZ (1) NZ182934A (da)
PH (1) PH14035A (da)
PT (1) PT66006B (da)
SE (1) SE432253B (da)
SG (1) SG63382G (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889713A (fr) * 1980-07-25 1982-01-25 Sandoz Sa Nouveaux derives de l'ergoline, leur preparation et leur application comme medicaments
CH654838A5 (fr) * 1980-07-25 1986-03-14 Sandoz Ag Ergolinderivate, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen.
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
GB2112382B (en) * 1981-11-06 1985-03-06 Erba Farmitalia Ergoline derivatives
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3216870A1 (de) * 1982-05-03 1983-11-03 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische zubereitungen mit zytostatischer wirkung
HU196399B (en) * 1983-02-16 1988-11-28 Sandoz Ag Process for producing ergoline derivatives and pharmaceutical compositions comprising such compounds
CH652719A5 (en) * 1983-02-16 1985-11-29 Sandoz Ag Ergoline derivatives, their preparation and use
CH664568A5 (de) * 1984-01-12 1988-03-15 Sandoz Ag 8-alpha-acylaminoergoline.
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
HU195810B (en) * 1984-12-24 1988-07-28 Sandoz Ag Process for preparing new 8alpha-acyl-amino-ergoline derivatives and pharmaceutical compositions containing such compounds
HU193317B (en) * 1985-06-12 1987-09-28 Richter Gedeon Vegyeszet Process for producing 2-bromo-alpha-ergochristin
US4801712A (en) * 1985-06-24 1989-01-31 Eli Lilly And Company 2-Alkyl(or phenyl)thio-6-n-alkylergolines are dopamine D-1 antagonists without D-2 agonist activity
DE3535929A1 (de) * 1985-10-04 1987-04-09 Schering Ag 1,2-disubstituierte ergolinderivate
HU196598B (en) * 1986-04-25 1988-12-28 Richter Gedeon Vegyeszet Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
GB8615471D0 (en) * 1986-06-25 1986-07-30 Erba Farmitalia T-butyl ergoline derivatives
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement
AT392945B (de) * 1988-06-27 1991-07-10 Gerhard Mader Ges M B H Ing Lager- und transportbehaelter fuer schuettgueter und lose materialien
IT1232692B (it) * 1989-08-04 1992-03-04 Poli Ind Chimica Spa Derivati ergolinici con attivita' dopaminergica
AU2635599A (en) * 1999-03-17 2000-10-04 Eugen Eigenmann Use of prolactin inhibitors for the treatment of fertility problems in animal species

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2533698A (en) * 1950-12-12 Urethanes containing the lysergic
US3232943A (en) * 1966-02-01 Cyanoethyl ergolene and ergoline derivatives
US3270020A (en) * 1966-08-30 Dihydro ergocornine
US3245996A (en) * 1966-04-12 Cyanoethyl lysergol
US3185695A (en) * 1965-05-25 Dbwethyl-ergoline ii derivatives
CH415658A (de) * 1962-06-18 1966-06-30 Sandoz Ag Verfahren zur Herstellung von neuen Urethanen
BE712054A (da) * 1967-03-16 1968-07-15
US3920664A (en) * 1972-07-21 1975-11-18 Lilly Co Eli D-2-halo-6-alkyl-8-substituted ergolines and related compounds
US3880856A (en) * 1973-06-29 1975-04-29 Lilly Co Eli Ergoline dimers
CS171480B1 (da) * 1974-03-19 1976-10-29
CH605936A5 (en) * 1974-07-19 1978-10-13 Sandoz Ag 8-Alpha-(Amino-or cyanomethyl)-ergoline derivs
GB1517972A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-cyanomethylergoline i
US3904757A (en) * 1974-08-08 1975-09-09 Lilly Co Eli Treatment of parkinsonism
US3922347A (en) * 1974-12-19 1975-11-25 Lilly Co Eli Method of inhibiting prolactin secretion with 8-acylaminoergolenes

Also Published As

Publication number Publication date
FR2336135B1 (da) 1980-03-07
DK146205C (da) 1983-12-27
NZ182934A (en) 1978-12-18
PH14035A (en) 1980-12-12
HK3483A (en) 1983-01-20
JPS5278900A (en) 1977-07-02
GB1567484A (en) 1980-05-14
PT66006A (fr) 1977-01-01
NL7614018A (nl) 1977-06-27
IE44242B1 (en) 1981-09-23
SG63382G (en) 1983-09-09
IL51133A (en) 1981-11-30
AU514288B2 (en) 1981-02-05
DK562376A (da) 1977-06-24
DK146205B (da) 1983-07-25
CA1092100A (en) 1980-12-23
DE2656344A1 (de) 1977-07-07
ES454442A1 (es) 1978-03-01
PT66006B (fr) 1978-07-06
JPS6133031B2 (da) 1986-07-31
FR2336135A1 (fr) 1977-07-22
IL51133A0 (en) 1977-02-28
FI763587A (da) 1977-06-24
SE7614085L (sv) 1977-06-24
MY8400060A (en) 1984-12-31
US4348391A (en) 1982-09-07
SE432253B (sv) 1984-03-26
DE2656344C2 (da) 1990-11-08
AU2079376A (en) 1978-06-29

Similar Documents

Publication Publication Date Title
DK49676A (da) Fremgangsmade til fremstilling af hypolipidemiske midler
DK567376A (da) Fremgangsmade til fremstilling af quinazolonderivater
DK554179A (da) Fremgangsmaade til fremstilling af ergolinderivater
DK324176A (da) Fremgangsmade til fremstilling af orthoaminobutyrophenonderivater
DK528976A (da) Fremgangsmade til fremstilling af indazolderivater
DK298476A (da) Fremgangsmade til fremstilling af 5-benzyl-2-oxazolidonderivater
DK452578A (da) Fremgangsmaade til fremstilling af furanderivater
DK575576A (da) Fremgangsmade til fremstilling af krystallinske former af natrium-cefamandol
DK137275C (da) Fremgangsmaade til fremstilling af 4-oxo-hexahydropyrazinoisoquinolinderivater
DK565676A (da) Fremgangsmade til fremstilling af klavamderivater
DK122876A (da) Fremgangsmade til fremstilling af foderstoffer
DK343976A (da) Fremgangsmade til fremstilling af 5-androsten-17-on-derivater
DK551076A (da) Fremgangsmade til fremstilling af trifluormethylthio-derivater af cyproheptadin
DK253676A (da) Fremgangsmade til fremstilling af cycloheptathiopenderivater
DK251176A (da) Fremgangsmade til fremstilling af cyklopropanolderivater
DK141532C (da) Fremgangsmaade til fremstilling af 21-hydroxy-16-pregnen-20-onderivater
DK142845C (da) Analogifremgangsmaade til fremstilling af imidazolderivater
DK541776A (da) Fremgangsmade til fremstilling af prostaglandiner
DK366676A (da) Fremgangsmade til fremstilling af slagseje polyvinylaromater
DK562076A (da) Fremgangsmade til fremstilling af azetidinonderivater
DK62876A (da) Fremgangsmade til fremstilling af benzo-cyclohepta-thiophenderivater
DK66476A (da) Fremgangsmade til fremstilling af substituerede indanylpropionsyrer
DK22276A (da) Fremgangsmade til fremstilling af thiazol-5-methanolderivater
DK374778A (da) Fremgangsmaade til fremstilling af ergolinderivater
DK136653B (da) Fremgangsmåde til fremstilling af thieno-pyridinderivater.