GR62072B - Preparation process of substituted n-methylene derivatives of thienamycin - Google Patents

Preparation process of substituted n-methylene derivatives of thienamycin

Info

Publication number
GR62072B
GR62072B GR52223A GR760152223A GR62072B GR 62072 B GR62072 B GR 62072B GR 52223 A GR52223 A GR 52223A GR 760152223 A GR760152223 A GR 760152223A GR 62072 B GR62072 B GR 62072B
Authority
GR
Greece
Prior art keywords
thienamycin
substituted
preparation process
methylene derivatives
methylene
Prior art date
Application number
GR52223A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GR62072B publication Critical patent/GR62072B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR52223A 1975-11-21 1976-11-20 Preparation process of substituted n-methylene derivatives of thienamycin GR62072B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US63429675A 1975-11-21 1975-11-21
US67626176A 1976-04-12 1976-04-12
US73365476A 1976-10-18 1976-10-18

Publications (1)

Publication Number Publication Date
GR62072B true GR62072B (en) 1979-02-20

Family

ID=27417545

Family Applications (1)

Application Number Title Priority Date Filing Date
GR52223A GR62072B (en) 1975-11-21 1976-11-20 Preparation process of substituted n-methylene derivatives of thienamycin

Country Status (27)

Country Link
AT (1) AT358168B (el)
AU (1) AU512383B2 (el)
BG (1) BG34037A3 (el)
CA (1) CA1083577A (el)
CH (2) CH632510A5 (el)
DD (1) DD127742A5 (el)
DE (1) DE2652679A1 (el)
DK (1) DK157401C (el)
EG (1) EG12261A (el)
ES (1) ES453501A1 (el)
FI (1) FI62306C (el)
FR (1) FR2332012A1 (el)
GB (1) GB1570990A (el)
GR (1) GR62072B (el)
HK (1) HK29683A (el)
HU (1) HU180865B (el)
IE (1) IE44433B1 (el)
IL (1) IL50911A (el)
KE (1) KE3286A (el)
NL (1) NL189297C (el)
NO (1) NO153298C (el)
NZ (1) NZ182630A (el)
PH (1) PH16714A (el)
PL (1) PL110937B1 (el)
PT (1) PT65865B (el)
SE (1) SE427841B (el)
SG (1) SG10983G (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593524A (en) * 1976-11-19 1981-07-15 Merck & Co Inc 1-carba-2-penem-3-carboxylic acids
DK170778A (da) * 1977-05-05 1979-01-15 Merck & Co Inc Fremgangsmaade til fremstilling af n-alkyl-n-iminomethyl-derivater af thienamycin
US4232030A (en) * 1977-09-15 1980-11-04 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone
DK153486C (da) * 1978-07-03 1988-11-28 Merck & Co Inc Analogifremgangsmaade til fremstilling af krystallinsk n-formimidoyl-thienamycin-monohydrat
EP0044170A1 (en) * 1980-07-11 1982-01-20 Beecham Group Plc Beta-lactam antibiotics, their preparation and use
CA2089261A1 (en) * 1990-08-30 1992-03-01 John F.W. Keana Substituted amidines having high binding to the sigma receptor and the use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348985A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Esters of cephalosporin compounds
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics

Also Published As

Publication number Publication date
FI62306B (fi) 1982-08-31
IL50911A (en) 1981-01-30
IE44433L (en) 1977-05-21
HU180865B (en) 1983-04-29
FR2332012B1 (el) 1978-11-17
AU1964776A (en) 1978-05-25
KE3286A (en) 1983-06-17
DE2652679A1 (de) 1977-06-02
NO153298B (no) 1985-11-11
PT65865B (en) 1978-10-12
DD127742A5 (de) 1977-10-12
NZ182630A (en) 1979-07-11
GB1570990A (en) 1980-07-09
SE7612963L (sv) 1977-05-22
DK157401C (da) 1990-05-21
DK523576A (da) 1977-05-22
SG10983G (en) 1983-12-16
AT358168B (de) 1980-08-25
PL110937B1 (en) 1980-08-30
DE2652679C2 (el) 1990-03-01
BG34037A3 (en) 1983-06-15
FI62306C (fi) 1982-12-10
NO763958L (el) 1977-05-24
PL193809A1 (pl) 1978-01-16
EG12261A (en) 1978-12-31
DK157401B (da) 1990-01-02
FI763308A (el) 1977-05-22
HK29683A (en) 1983-08-26
IE44433B1 (en) 1981-12-02
NL189297B (nl) 1992-10-01
NL189297C (nl) 1993-03-01
NO153298C (no) 1986-02-19
PH16714A (en) 1984-01-25
CA1083577A (en) 1980-08-12
CH633800A5 (en) 1982-12-31
SE427841B (sv) 1983-05-09
ATA863476A (de) 1980-01-15
IL50911A0 (en) 1977-01-31
FR2332012A1 (fr) 1977-06-17
NL7612939A (nl) 1977-05-24
AU512383B2 (en) 1980-10-09
ES453501A1 (es) 1978-03-01
CH632510A5 (en) 1982-10-15
PT65865A (en) 1976-12-01

Similar Documents

Publication Publication Date Title
GR60854B (en) Preparation process of benzylidenic derivatives
GR59797B (en) Preparation process of thieno-pyridine derivatives
GR62109B (en) Preparation process of quinazolone derivatives
GR60336B (en) Preparation process of acylamino derivatives
HU171396B (hu) Sposob poluchenija proizvodnykh rifamicina
GR60383B (en) Preparation process of novel imidazole derivatives
GB1535291A (en) Process for the preparation of amoxycillin
HU171395B (hu) Sposob poluchenija proizvodnykh rifamicina
GR60380B (en) Preparation process of acylamino derivatives
ZA766973B (en) Substituted n-methylene derivatives of thienamycin
GR62072B (en) Preparation process of substituted n-methylene derivatives of thienamycin
CS189782B2 (en) Process for preparing derivatives of diaminoandrostane
GR61601B (en) Preparation process of novel heterocyclic derivatives
PT65460B (en) Process of preparation of pyrrolidine derivatives
CS191319B2 (en) Process for preparing derivatives of 2-nitro-3-phenylbenzofurane
CS191981B2 (en) Process for preparing derivatives of 5-androsten-17-one
CS191308B2 (en) Process for preparing derivatives of diarylhydroxybutylamines
CS189751B2 (en) Process for preparing derivatives of diphenyletheres
CS193070B2 (en) Process for preparing derivatives of n-methylurea
PT65120B (en) Process for the preparation of novel diureide derivatives
GR60337B (en) Preparation process of acylamino derivatives
HU172280B (hu) Sposob poluchenija proizvodnykh tetragidro-tieno-piridina
CH613691A5 (en) Process for the preparation of novel 1-indolinylguanidine derivatives
GB1477990A (en) Process for the preparation of thieno-pyridine derivatives
CS188986B2 (en) Process for preparing n-tricyclic derivatives of aminoazetidine