PH14127A - 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them - Google Patents

2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them

Info

Publication number
PH14127A
PH14127A PH16895A PH16895A PH14127A PH 14127 A PH14127 A PH 14127A PH 16895 A PH16895 A PH 16895A PH 16895 A PH16895 A PH 16895A PH 14127 A PH14127 A PH 14127A
Authority
PH
Philippines
Prior art keywords
benzomorphans
tetrahydrofurfuryl
oxy
salts
lower alkyl
Prior art date
Application number
PH16895A
Other languages
English (en)
Inventor
K Stockhaus
A Langbein
H Merz
G Walther
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of PH14127A publication Critical patent/PH14127A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PH16895A 1974-03-09 1975-03-10 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them PH14127A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
PH14127A true PH14127A (en) 1981-02-26

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
PH16895A PH14127A (en) 1974-03-09 1975-03-10 2-tetrahydrofurfuryl-5-lower alkyl-2'oxy-6,7-benzomorphans,salts thereof and compositions containing them

Country Status (25)

Country Link
JP (1) JPS5827275B2 (xx)
AT (1) AT344332B (xx)
BE (1) BE826440A (xx)
BG (3) BG25087A3 (xx)
CA (1) CA1049511A (xx)
CH (8) CH612425A5 (xx)
CS (1) CS188221B2 (xx)
DD (1) DD119236A5 (xx)
DE (1) DE2411382C3 (xx)
DK (1) DK137188C (xx)
ES (6) ES440346A1 (xx)
FI (1) FI63571C (xx)
FR (1) FR2262984B1 (xx)
GB (1) GB1496418A (xx)
HU (1) HU177408B (xx)
IE (1) IE40945B1 (xx)
IL (1) IL46760A (xx)
NL (1) NL7502724A (xx)
NO (1) NO141800C (xx)
PH (1) PH14127A (xx)
PL (3) PL93700B1 (xx)
RO (2) RO69617A (xx)
SE (1) SE421919B (xx)
SU (3) SU577982A3 (xx)
ZA (1) ZA751394B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
PT820432E (pt) * 1995-03-10 2001-09-28 Photocure Asa Esteres do acido 5-aminolevulinico como agentes fotossensibilizadores em fotoquimioterapia
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
TW200927115A (en) 2007-11-16 2009-07-01 Boehringer Ingelheim Int Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
EP2229368A1 (en) 2007-12-11 2010-09-22 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
WO2009102460A2 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
EP2291370B1 (en) 2008-05-01 2013-11-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134400A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2288596B1 (en) 2008-05-13 2016-11-30 Boehringer Ingelheim International GmbH Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2730499A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en) 2009-06-11 2011-01-27 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
CH620439A5 (en) 1980-11-28
FI63571B (fi) 1983-03-31
JPS5827275B2 (ja) 1983-06-08
BG24814A4 (en) 1978-05-12
FR2262984B1 (xx) 1978-07-28
ES440345A1 (es) 1977-03-01
NO141800B (no) 1980-02-04
CH622014A5 (en) 1981-03-13
PL93700B1 (xx) 1977-06-30
NO750773L (xx) 1975-09-10
CH622015A5 (en) 1981-03-13
SE7502592L (xx) 1975-09-10
ES440350A1 (es) 1977-03-16
NO141800C (no) 1980-06-04
PL93499B1 (xx) 1977-05-30
DE2411382C3 (de) 1979-09-06
IL46760A (en) 1978-12-17
CH620440A5 (en) 1980-11-28
CS188221B2 (en) 1979-02-28
BG25087A3 (en) 1978-07-12
BE826440A (fr) 1975-09-08
ZA751394B (en) 1976-11-24
RO69617A (ro) 1980-08-15
JPS50123675A (xx) 1975-09-29
DK137188B (da) 1978-01-30
ES440348A1 (es) 1977-06-01
CH620681A5 (en) 1980-12-15
CH612425A5 (en) 1979-07-31
IL46760A0 (en) 1975-05-22
DE2411382B2 (de) 1979-01-18
HU177408B (en) 1981-10-28
SU577983A3 (ru) 1977-10-25
ES440346A1 (es) 1977-03-01
AU7894275A (en) 1976-09-16
FI63571C (fi) 1983-07-11
CH622016A5 (en) 1981-03-13
CH622017A5 (en) 1981-03-13
SE421919B (sv) 1982-02-08
DE2411382A1 (de) 1975-09-18
NL7502724A (nl) 1975-09-11
FI750652A (xx) 1975-09-10
DK137188C (da) 1978-07-03
IE40945B1 (en) 1979-09-12
SU588916A3 (ru) 1978-01-15
AT344332B (de) 1978-07-10
FR2262984A1 (xx) 1975-10-03
ES440347A1 (es) 1977-06-01
GB1496418A (en) 1977-12-30
DK92975A (xx) 1975-09-10
CA1049511A (en) 1979-02-27
DD119236A5 (xx) 1976-04-12
IE40945L (en) 1975-09-09
PL93699B1 (xx) 1977-06-30
RO70051A (ro) 1980-12-30
SU577982A3 (ru) 1977-10-25
ES440349A1 (es) 1977-03-01
BG24813A4 (en) 1978-05-12
ATA153875A (de) 1977-11-15

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