PH12782A - Z-hydroxy-w-aminoalkyl derivatives of aminoglycoside antibiotics - Google Patents

Z-hydroxy-w-aminoalkyl derivatives of aminoglycoside antibiotics

Info

Publication number
PH12782A
PH12782A PH17665A PH17665A PH12782A PH 12782 A PH12782 A PH 12782A PH 17665 A PH17665 A PH 17665A PH 17665 A PH17665 A PH 17665A PH 12782 A PH12782 A PH 12782A
Authority
PH
Philippines
Prior art keywords
hydroxy
aminoglycoside antibiotics
aminoalkyl derivatives
aminoalkyl
derivatives
Prior art date
Application number
PH17665A
Other languages
English (en)
Inventor
J Moore
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PH12782A publication Critical patent/PH12782A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/228—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings
    • C07H15/23—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with only two saccharide radicals in the molecule, e.g. ambutyrosin, butyrosin, xylostatin, ribostamycin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH17665A 1974-10-26 1975-10-16 Z-hydroxy-w-aminoalkyl derivatives of aminoglycoside antibiotics PH12782A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4641274A GB1464401A (en) 1974-10-26 1974-10-26 Aminoglycosides

Publications (1)

Publication Number Publication Date
PH12782A true PH12782A (en) 1979-08-17

Family

ID=10441164

Family Applications (1)

Application Number Title Priority Date Filing Date
PH17665A PH12782A (en) 1974-10-26 1975-10-16 Z-hydroxy-w-aminoalkyl derivatives of aminoglycoside antibiotics

Country Status (28)

Country Link
JP (1) JPS5519237B2 (fr)
AR (1) AR205593A1 (fr)
AT (1) AT340051B (fr)
BE (1) BE834864A (fr)
BG (1) BG24821A3 (fr)
CA (1) CA1039275A (fr)
CH (1) CH601339A5 (fr)
CS (1) CS195712B2 (fr)
DD (1) DD122522A5 (fr)
DE (1) DE2547738C3 (fr)
DK (1) DK147075C (fr)
EG (1) EG11975A (fr)
ES (1) ES442051A1 (fr)
FI (1) FI752951A (fr)
FR (1) FR2289202A1 (fr)
GB (1) GB1464401A (fr)
HU (1) HU172060B (fr)
IE (1) IE42452B1 (fr)
IL (1) IL48263A (fr)
LU (1) LU73644A1 (fr)
NL (1) NL162081C (fr)
NZ (1) NZ179050A (fr)
PH (1) PH12782A (fr)
PL (1) PL99933B1 (fr)
RO (1) RO72878A (fr)
SE (1) SE7511945L (fr)
SU (1) SU617017A3 (fr)
ZA (1) ZA756326B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2860513D1 (en) * 1977-06-24 1981-04-09 Scherico Ltd Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
JPS57118475U (fr) * 1981-01-14 1982-07-22

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606076A5 (fr) * 1973-08-06 1978-10-13 Scherico Ltd

Also Published As

Publication number Publication date
CA1039275A (fr) 1978-09-26
BG24821A3 (en) 1978-05-12
CH601339A5 (fr) 1978-07-14
ZA756326B (en) 1976-09-29
IE42452B1 (en) 1980-08-13
FR2289202A1 (fr) 1976-05-28
JPS5168543A (fr) 1976-06-14
NL162081C (nl) 1980-04-15
PL99933B1 (pl) 1978-08-31
EG11975A (en) 1978-06-30
RO72878B (ro) 1983-06-30
IL48263A0 (en) 1975-12-31
SE7511945L (sv) 1976-04-27
AU8598175A (en) 1976-12-09
LU73644A1 (fr) 1977-05-31
AR205593A1 (es) 1976-05-14
DK147075C (da) 1984-11-05
DK147075B (da) 1984-04-02
IE42452L (en) 1976-04-26
JPS5519237B2 (fr) 1980-05-24
BE834864A (fr) 1976-04-26
RO72878A (fr) 1983-07-07
DE2547738C3 (de) 1978-08-03
NZ179050A (en) 1978-03-06
ATA809575A (de) 1977-03-15
SU617017A3 (ru) 1978-07-25
DK481175A (da) 1976-04-27
CS195712B2 (en) 1980-02-29
DD122522A5 (fr) 1976-10-12
GB1464401A (en) 1977-02-16
FI752951A (fr) 1976-04-27
NL162081B (nl) 1979-11-15
NL7512465A (nl) 1976-04-28
FR2289202B1 (fr) 1978-11-10
DE2547738B2 (de) 1977-12-01
DE2547738A1 (de) 1976-05-06
HU172060B (hu) 1978-05-28
ES442051A1 (es) 1977-04-01
AT340051B (de) 1977-11-25
IL48263A (en) 1978-03-10

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