IL46467A0 - Aminoacyl derivatives of aminoglycoside antibiotics - Google Patents

Aminoacyl derivatives of aminoglycoside antibiotics

Info

Publication number
IL46467A0
IL46467A0 IL46467A IL4646775A IL46467A0 IL 46467 A0 IL46467 A0 IL 46467A0 IL 46467 A IL46467 A IL 46467A IL 4646775 A IL4646775 A IL 4646775A IL 46467 A0 IL46467 A0 IL 46467A0
Authority
IL
Israel
Prior art keywords
aminoglycoside antibiotics
aminoacyl derivatives
aminoacyl
derivatives
aminoglycoside
Prior art date
Application number
IL46467A
Other versions
IL46467A (en
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/452,586 external-priority patent/US4029882A/en
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of IL46467A0 publication Critical patent/IL46467A0/en
Publication of IL46467A publication Critical patent/IL46467A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL46467A 1974-03-19 1975-01-21 1-n-derivatives of 4,6-di-(amino-glycosyl)-1,3-diaminocylitols and method for their preparation IL46467A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45257174A 1974-03-19 1974-03-19
US05/452,586 US4029882A (en) 1974-03-19 1974-03-19 Selective acylation of the C-1 amino group of aminoglycoside antibiotics

Publications (2)

Publication Number Publication Date
IL46467A0 true IL46467A0 (en) 1975-04-25
IL46467A IL46467A (en) 1978-10-31

Family

ID=27036813

Family Applications (1)

Application Number Title Priority Date Filing Date
IL46467A IL46467A (en) 1974-03-19 1975-01-21 1-n-derivatives of 4,6-di-(amino-glycosyl)-1,3-diaminocylitols and method for their preparation

Country Status (10)

Country Link
AR (1) AR207582A1 (en)
BG (1) BG26400A3 (en)
CH (1) CH612946A5 (en)
DE (1) DE2502296C2 (en)
FR (1) FR2264553B1 (en)
GB (1) GB1494129A (en)
HK (1) HK7681A (en)
IE (1) IE40796B1 (en)
IL (1) IL46467A (en)
MY (1) MY8100350A (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136254A (en) * 1976-06-17 1979-01-23 Schering Corporation Process of selectively blocking amino functions in aminoglycosides using transition metal salts and intermediates used thereby
DE2753769A1 (en) * 1977-12-02 1979-06-13 Bayer Ag 1-N-4,6-DI-O- (AMINOGLYCOSYL) -1,3-DIAMINO-CYCLITOL DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND USE
DE2921973A1 (en) * 1979-05-30 1980-12-11 Bayer Ag SISOMICIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
DE3101376A1 (en) * 1981-01-17 1982-09-02 Bayer Ag, 5090 Leverkusen SISOMICIN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
ES2689539T3 (en) 2006-04-03 2018-11-14 Technion Research & Development Foundation Ltd. Novel aminoglycosides and their uses in the treatment of genetic disorders
CA2706369C (en) 2007-11-21 2014-03-25 Achaogen, Inc. Antibacterial aminoglycoside analogs
CA2761674C (en) * 2009-05-14 2016-11-29 Achaogen, Inc. Treatment of klebsiella pneumoniae infections with antibacterial aminoglycoside compounds
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs

Also Published As

Publication number Publication date
GB1494129A (en) 1977-12-07
AR207582A1 (en) 1976-10-15
MY8100350A (en) 1981-12-31
IE40796B1 (en) 1979-08-15
IL46467A (en) 1978-10-31
AU7747775A (en) 1976-07-22
IE40796L (en) 1975-09-19
CH612946A5 (en) 1979-08-31
FR2264553A1 (en) 1975-10-17
DE2502296C2 (en) 1983-09-22
HK7681A (en) 1981-03-20
FR2264553B1 (en) 1978-12-01
DE2502296A1 (en) 1975-09-25
BG26400A3 (en) 1979-03-15

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