PH12012500643A1 - Novel phenol derivative - Google Patents
Novel phenol derivativeInfo
- Publication number
- PH12012500643A1 PH12012500643A1 PH1/2012/500643A PH12012500643A PH12012500643A1 PH 12012500643 A1 PH12012500643 A1 PH 12012500643A1 PH 12012500643 A PH12012500643 A PH 12012500643A PH 12012500643 A1 PH12012500643 A1 PH 12012500643A1
- Authority
- PH
- Philippines
- Prior art keywords
- group
- lower alkyl
- salt
- derivative
- hydrogen atom
- Prior art date
Links
- 150000002989 phenols Chemical class 0.000 title abstract 2
- 150000003839 salts Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001188 haloalkyl group Chemical group 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical class [H]N([H])C(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 230000003424 uricosuric effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009227402A JP5325065B2 (ja) | 2009-09-30 | 2009-09-30 | 新規フェノール誘導体 |
| PCT/JP2010/066925 WO2011040449A1 (ja) | 2009-09-30 | 2010-09-29 | 新規フェノール誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12012500643A1 true PH12012500643A1 (en) | 2012-11-12 |
Family
ID=43826265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH1/2012/500643A PH12012500643A1 (en) | 2009-09-30 | 2010-09-29 | Novel phenol derivative |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8367843B2 (OSRAM) |
| EP (1) | EP2484669B1 (OSRAM) |
| JP (1) | JP5325065B2 (OSRAM) |
| KR (1) | KR101647174B1 (OSRAM) |
| CN (1) | CN102639518B (OSRAM) |
| AU (1) | AU2010301675B2 (OSRAM) |
| BR (1) | BR112012007069B1 (OSRAM) |
| CA (1) | CA2775309C (OSRAM) |
| DK (1) | DK2484669T3 (OSRAM) |
| ES (1) | ES2549603T3 (OSRAM) |
| HU (1) | HUE026007T2 (OSRAM) |
| IL (1) | IL218519A (OSRAM) |
| IN (1) | IN2012DN02551A (OSRAM) |
| MX (1) | MX2012003392A (OSRAM) |
| MY (1) | MY160394A (OSRAM) |
| NZ (1) | NZ598582A (OSRAM) |
| PH (1) | PH12012500643A1 (OSRAM) |
| PL (1) | PL2484669T3 (OSRAM) |
| PT (1) | PT2484669E (OSRAM) |
| RU (1) | RU2536689C2 (OSRAM) |
| TW (1) | TWI461195B (OSRAM) |
| WO (1) | WO2011040449A1 (OSRAM) |
| ZA (1) | ZA201201895B (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5851802B2 (ja) | 2011-03-30 | 2016-02-03 | 富士重工業株式会社 | 炭素繊維強化樹脂複合材用ドリル |
| WO2015191034A1 (en) * | 2014-06-09 | 2015-12-17 | Baylor College Of Medicine | Small molecule xanthine oxidase inhibitors and methods of use |
| WO2017038799A1 (ja) * | 2015-09-04 | 2017-03-09 | サントリーホールディングス株式会社 | ウレアーゼ活性阻害剤 |
| HUE051448T2 (hu) * | 2015-09-10 | 2021-03-01 | Jiangsu Atom Bioscience | Imidazo[1,2a]piridinek hiperurikémia vagy köszvény kezelésére vagy megelõzésére |
| CN105675557B (zh) * | 2016-01-07 | 2019-01-25 | 济南大学 | 基于苯炔荧光试剂检测硫脲含量的新方法 |
| EP3957629B1 (en) | 2016-07-18 | 2023-09-06 | Arthrosi Therapeutics, Inc. | Process for making deuterated hydroxy-benzbromarone and intermediates thereof |
| BR112019018840B1 (pt) | 2017-04-28 | 2023-12-19 | Fuji Yakuhin Co., Ltd | Forma cristalina de 3-(3,5-dicloro-4-hidroxibenzoil)-1,1-dioxo-2,3-dihidro 1,3 -benzotiazol |
| CN109928890B (zh) * | 2017-12-15 | 2021-11-09 | 重庆常捷医药有限公司 | 一种托伐普坦中间体2-甲基-4-n-(2-甲基苯甲酰)苯甲酸的制备方法 |
| CA3121624A1 (en) | 2018-12-06 | 2020-06-11 | Arthrosi Therapeutics, Inc. | Methods for treating or preventing gout or hyperuricemia |
| KR20210100677A (ko) | 2018-12-06 | 2021-08-17 | 아쓰로시 테라퓨틱스, 인크. | 통풍 또는 고뇨산혈증의 치료 또는 예방을 위한 화합물의 결정형 |
| EP4074313A4 (en) * | 2019-12-09 | 2024-01-03 | Fuji Yakuhin Co., Ltd. | SOLID PHARMACEUTICAL PREPARATION |
| CN111662247A (zh) * | 2020-07-17 | 2020-09-15 | 苏州明锐医药科技有限公司 | 一种多替诺德的合成方法 |
| CN111675675A (zh) * | 2020-07-17 | 2020-09-18 | 苏州明锐医药科技有限公司 | 多替诺德的制备方法 |
| CN112430221B (zh) * | 2020-11-20 | 2023-06-23 | 成都诺和晟泰生物科技有限公司 | 用于预防、治疗或减轻高尿酸血症或痛风的化合物及其应用 |
| WO2022169974A1 (en) | 2021-02-05 | 2022-08-11 | Nexys Therapeutics, Inc. | Inhibitors of urat1 and pharmaceutical uses thereof |
| CN114903879B (zh) * | 2022-06-23 | 2023-10-31 | 东北大学 | 3-烃基苯酚衍生物在制备预防或治疗高脂血症及相关代谢性疾病产品中的用途 |
| CN115160314B (zh) * | 2022-07-28 | 2023-12-05 | 南方医科大学 | 杂环芳酰胺类化合物及其制备方法和应用 |
| WO2025085662A1 (en) | 2023-10-17 | 2025-04-24 | Vanderbilt University | Compounds for tocolytic use |
| CN118580197A (zh) * | 2023-11-16 | 2024-09-03 | 广东东阳光药业股份有限公司 | 一种多替诺雷制备方法及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3720683A (en) * | 1970-09-02 | 1973-03-13 | Squibb & Sons Inc | 2-phenyl-3-acylbenzothiazolines and their oxides |
| US7521570B2 (en) | 2004-06-10 | 2009-04-21 | Torli Pharmaceutical Co., Ltd. | Medicinal compositions containing 6-hydroxybenzbromarone or salts thereof |
| AR051780A1 (es) * | 2004-11-29 | 2007-02-07 | Japan Tobacco Inc | Compuestos en anillo fusionados que contienen nitrogeno y utilizacion de los mismos |
| JP3988832B2 (ja) | 2004-11-29 | 2007-10-10 | 日本たばこ産業株式会社 | 窒素含有縮合環化合物及びその用途 |
| EP1985297A1 (en) * | 2006-01-27 | 2008-10-29 | Japan Tobacco, Inc. | Carboxylic acid compound and use thereof |
| US20080305169A1 (en) * | 2006-05-26 | 2008-12-11 | Japan Tobacco Inc. | Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds |
| US20080064871A1 (en) * | 2006-05-26 | 2008-03-13 | Japan Tobacco Inc. | Production Method of Nitrogen-Containing Fused Ring Compounds |
| WO2008062740A1 (fr) * | 2006-11-20 | 2008-05-29 | Japan Tobacco Inc. | Composé azoté à anneaux fusionnés et son utilisation |
-
2009
- 2009-09-30 JP JP2009227402A patent/JP5325065B2/ja active Active
-
2010
- 2010-09-29 ES ES10820564.2T patent/ES2549603T3/es active Active
- 2010-09-29 MY MYPI2012001060A patent/MY160394A/en unknown
- 2010-09-29 PT PT108205642T patent/PT2484669E/pt unknown
- 2010-09-29 KR KR1020127007939A patent/KR101647174B1/ko active Active
- 2010-09-29 US US13/499,190 patent/US8367843B2/en active Active
- 2010-09-29 NZ NZ598582A patent/NZ598582A/xx unknown
- 2010-09-29 AU AU2010301675A patent/AU2010301675B2/en active Active
- 2010-09-29 PH PH1/2012/500643A patent/PH12012500643A1/en unknown
- 2010-09-29 WO PCT/JP2010/066925 patent/WO2011040449A1/ja not_active Ceased
- 2010-09-29 CN CN201080042866.9A patent/CN102639518B/zh active Active
- 2010-09-29 RU RU2012117786/04A patent/RU2536689C2/ru active
- 2010-09-29 TW TW099132910A patent/TWI461195B/zh active
- 2010-09-29 MX MX2012003392A patent/MX2012003392A/es active IP Right Grant
- 2010-09-29 IN IN2551DEN2012 patent/IN2012DN02551A/en unknown
- 2010-09-29 BR BR112012007069-0A patent/BR112012007069B1/pt active IP Right Grant
- 2010-09-29 CA CA2775309A patent/CA2775309C/en active Active
- 2010-09-29 DK DK10820564.2T patent/DK2484669T3/en active
- 2010-09-29 HU HUE10820564A patent/HUE026007T2/en unknown
- 2010-09-29 PL PL10820564T patent/PL2484669T3/pl unknown
- 2010-09-29 EP EP10820564.2A patent/EP2484669B1/en active Active
-
2012
- 2012-03-07 IL IL218519A patent/IL218519A/en active IP Right Grant
- 2012-03-14 ZA ZA2012/01895A patent/ZA201201895B/en unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12012500643A1 (en) | Novel phenol derivative | |
| MX2009005217A (es) | Compuestos heterociclicos que contienen nitrogeno y metodos de uso de los mismos. | |
| MX2009004441A (es) | Derivados de indazol utiles como inhibidores de las isoformas de higado. | |
| PT1940839E (pt) | Inibidores de piridopirimidinona pi3k alfa | |
| TW200833675A (en) | Nicotinamide derivatives | |
| MX2011013771A (es) | Derivados de imidazolidin-2-ona 1,3-disustituida como inhibidores de cyp17. | |
| MX2011011136A (es) | Eteres diarilicos. | |
| TW200618800A (en) | Heterocyclic compounds | |
| MY149622A (en) | Pyrazoles as 11-beta-hsd-1 | |
| WO2009016460A8 (en) | Pyrazole compounds and their use as raf inhibitors | |
| UA89787C2 (ru) | Фторгликозидные производные пиразолов, лекарственное средство, которое содержит их, и их применение | |
| MX2009008540A (es) | Inhibidores de virus de hepatitis c macrociclicos sustituidos con pirimidina. | |
| MX2007003546A (es) | Derivados de indozolona como inhibidores de 11-beta- hidroxiesteroide-deshidrogenasa. | |
| TNSN08191A1 (en) | Kinase inhibitors | |
| MX2010009922A (es) | Activadores de piridazinona glucocinasa. | |
| TNSN06377A1 (en) | Combinations of glycopyrrolate and beta2 adrenoceptor agonists | |
| MX2007012212A (es) | 1h-pirazol 4-carboxilamidas, su preparacion y su uso como 11-beta-hidroxiesteroide deshidrogenasa. | |
| TN2009000178A1 (en) | Substituted pyrazole and triazole compounds as ksp inhibitors | |
| MX2010001566A (es) | Derivado de aminopirazolamida. | |
| TW200745066A (en) | Novel PTP1B inhibitors | |
| ATE553106T1 (de) | Heteroarylpyrrolopyridinone als kinaseinhibitoren | |
| MX2007004248A (es) | Derivados heterociclicos de bisarilurea sustituidos como inhibidores de cinasa. | |
| TW200726764A (en) | N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | |
| TW200728298A (en) | Thiophene compounds and thrombopoietin receptor activators | |
| WO2007017728A3 (en) | Novel heterocyclic compounds |