PE23298A1 - Forma cristalina alternativa de tazofelona - Google Patents

Forma cristalina alternativa de tazofelona

Info

Publication number
PE23298A1
PE23298A1 PE1996000641A PE00064196A PE23298A1 PE 23298 A1 PE23298 A1 PE 23298A1 PE 1996000641 A PE1996000641 A PE 1996000641A PE 00064196 A PE00064196 A PE 00064196A PE 23298 A1 PE23298 A1 PE 23298A1
Authority
PE
Peru
Prior art keywords
crystalline form
tazofelona
year
refers
values
Prior art date
Application number
PE1996000641A
Other languages
English (en)
Inventor
Marvin Martin Hansen
Allen Robert Harkness
Susan Marie Reutzel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of PE23298A1 publication Critical patent/PE23298A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

SE REFIERE A LA FORMA CRISTALINA II, DEL COMPUESTO ANTIINFLAMATORIO (�)-5-{[3,5-BIS(1,1-DIMETIL ETIL)-4-HIDROXIFENIL]METIL}-4-TIAZOLIDINONA, DE FORMULA (A), CARACTERIZADO POR UN PATRON DE DIFRACCION EN POLVO DE RAYOS X, OBTENIDO CON UNA RADIACION DE CuKO, QUE COMPRENDE 5 VALORES (d) ESPACIO INTERPLANAR, TALES COMO: 5,64 A�; 5,16 A�; 4,90 A�; 4,66 A�; 4,49 A�. TAMBIEN SE REFIERE AL PROCESO DE OBTENCION DE LA FORMA II, QUE COMPRENDE: 1) SUSPENDER LA FORMA CRISTALINA (I) [ QUE COMPRENDE 3 VALORES (d): 7,20 A�; 4,84 A�; 4,76 A� ] EN UN DISOLVENTE ORGANICO, TAL COMO: (ACETATO DE ETILO, TOLUENO o HEPTANO):ACETATO DE ETILO 1:1, A TEMPERATURA AMBIENTE; 2) AGITAR LA SUSPENSION
PE1996000641A 1995-09-07 1996-09-02 Forma cristalina alternativa de tazofelona PE23298A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US335695P 1995-09-07 1995-09-07

Publications (1)

Publication Number Publication Date
PE23298A1 true PE23298A1 (es) 1998-05-05

Family

ID=21705475

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000641A PE23298A1 (es) 1995-09-07 1996-09-02 Forma cristalina alternativa de tazofelona

Country Status (29)

Country Link
EP (1) EP0761656B1 (es)
JP (1) JPH11514978A (es)
KR (1) KR19990044453A (es)
CN (1) CN1082958C (es)
AR (2) AR003483A1 (es)
AT (1) ATE198476T1 (es)
AU (1) AU716684B2 (es)
BR (1) BR9610201A (es)
CA (1) CA2231132A1 (es)
CO (1) CO4750653A1 (es)
CZ (1) CZ68098A3 (es)
DE (1) DE69611407T2 (es)
DK (1) DK0761656T3 (es)
EA (1) EA000258B1 (es)
ES (1) ES2153081T3 (es)
GR (1) GR3035656T3 (es)
HU (1) HUP9901458A3 (es)
IN (1) IN182320B (es)
MY (1) MY132351A (es)
NO (1) NO309719B1 (es)
NZ (1) NZ316810A (es)
PE (1) PE23298A1 (es)
PL (1) PL325602A1 (es)
PT (1) PT761656E (es)
SI (1) SI0761656T1 (es)
TR (1) TR199800398T1 (es)
TW (1) TW460471B (es)
WO (1) WO1997009320A1 (es)
ZA (1) ZA967422B (es)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US538690A (en) * 1895-05-07 Automatic watering-trough for animals
IL96654A (en) * 1989-12-21 1995-06-29 Lilly Co Eli Sutral derivatives containing hydroxybenzyl and sulfur-converted, and pharmaceutical preparations containing them
US5216002A (en) * 1989-12-21 1993-06-01 Eli Lilly And Company Method of treating inflammatory bowel disease

Also Published As

Publication number Publication date
HUP9901458A3 (en) 2000-05-29
GR3035656T3 (en) 2001-06-29
HUP9901458A2 (hu) 1999-09-28
TR199800398T1 (xx) 1998-05-21
CO4750653A1 (es) 1999-03-31
AU6912796A (en) 1997-03-27
AR003484A1 (es) 1998-08-05
CN1200730A (zh) 1998-12-02
CZ68098A3 (cs) 1998-08-12
ES2153081T3 (es) 2001-02-16
EA000258B1 (ru) 1999-02-25
AU716684B2 (en) 2000-03-02
SI0761656T1 (en) 2001-06-30
EP0761656B1 (en) 2001-01-03
ZA967422B (en) 1998-03-02
DE69611407D1 (de) 2001-02-08
NO980913L (no) 1998-03-03
WO1997009320A1 (en) 1997-03-13
MX9801705A (es) 1998-05-31
PL325602A1 (en) 1998-08-03
JPH11514978A (ja) 1999-12-21
DE69611407T2 (de) 2001-06-13
IN182320B (es) 1999-03-20
AR003483A1 (es) 1998-08-05
ATE198476T1 (de) 2001-01-15
CA2231132A1 (en) 1997-03-13
BR9610201A (pt) 1998-08-11
NO980913D0 (no) 1998-03-03
CN1082958C (zh) 2002-04-17
NO309719B1 (no) 2001-03-19
EP0761656A1 (en) 1997-03-12
TW460471B (en) 2001-10-21
MY132351A (en) 2007-10-31
PT761656E (pt) 2001-04-30
DK0761656T3 (da) 2001-02-05
NZ316810A (en) 1999-07-29
KR19990044453A (ko) 1999-06-25
EA199800275A1 (ru) 1998-08-27

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed