PE20211816A1 - Proceso de elaboracion de alfa-cetoglutarato de calcio - Google Patents
Proceso de elaboracion de alfa-cetoglutarato de calcioInfo
- Publication number
- PE20211816A1 PE20211816A1 PE2021000354A PE2021000354A PE20211816A1 PE 20211816 A1 PE20211816 A1 PE 20211816A1 PE 2021000354 A PE2021000354 A PE 2021000354A PE 2021000354 A PE2021000354 A PE 2021000354A PE 20211816 A1 PE20211816 A1 PE 20211816A1
- Authority
- PE
- Peru
- Prior art keywords
- alpha
- ketoglutarate
- salt
- calcium
- cetoglutarate
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- KPGXRSRHYNQIFN-UHFFFAOYSA-L 2-oxoglutarate(2-) Chemical class [O-]C(=O)CCC(=O)C([O-])=O KPGXRSRHYNQIFN-UHFFFAOYSA-L 0.000 abstract 5
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 abstract 2
- 159000000007 calcium salts Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 102000013530 TOR Serine-Threonine Kinases Human genes 0.000 abstract 1
- 108010065917 TOR Serine-Threonine Kinases Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 abstract 1
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 abstract 1
- 230000002715 bioenergetic effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000005787 mitochondrial ATP synthesis coupled electron transport Effects 0.000 abstract 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/418—Preparation of metal complexes containing carboxylic acid moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736320P | 2018-09-25 | 2018-09-25 | |
| PCT/US2019/052498 WO2020068705A1 (en) | 2018-09-25 | 2019-09-23 | Process of making calcium alpha-ketoglutarate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20211816A1 true PE20211816A1 (es) | 2021-09-14 |
Family
ID=69952136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2021000354A PE20211816A1 (es) | 2018-09-25 | 2019-09-23 | Proceso de elaboracion de alfa-cetoglutarato de calcio |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11802103B2 (OSRAM) |
| EP (1) | EP3856166A4 (OSRAM) |
| JP (1) | JP7499259B2 (OSRAM) |
| KR (1) | KR102833111B1 (OSRAM) |
| CN (1) | CN112955139B (OSRAM) |
| AU (1) | AU2019350699B2 (OSRAM) |
| BR (1) | BR112021005668A2 (OSRAM) |
| CA (1) | CA3112205A1 (OSRAM) |
| CL (1) | CL2021000728A1 (OSRAM) |
| CO (1) | CO2021004529A2 (OSRAM) |
| IL (1) | IL281761B2 (OSRAM) |
| MX (1) | MX2021003482A (OSRAM) |
| MY (1) | MY203278A (OSRAM) |
| PE (1) | PE20211816A1 (OSRAM) |
| PH (1) | PH12021550403A1 (OSRAM) |
| SG (1) | SG11202102204PA (OSRAM) |
| TW (1) | TWI863930B (OSRAM) |
| WO (1) | WO2020068705A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11802103B2 (en) | 2018-09-25 | 2023-10-31 | Ponce De Leon Health Designated Activity Company | Process of making calcium alpha-ketoglutarate |
| CN112941116B (zh) * | 2021-01-04 | 2022-12-02 | 上海朴颐化学科技有限公司 | 一种酶法制备α-酮戊二酸钙的方法 |
| CN114105761B (zh) * | 2021-11-19 | 2024-06-21 | 广东派特埃尔生物科技有限公司 | 一种α-酮戊二酸钠盐的合成工艺 |
| CN115974679A (zh) * | 2022-12-20 | 2023-04-18 | 绍兴市精益生物化工有限公司 | α-酮戊二酸钙盐制备方法 |
| CN119977789A (zh) * | 2025-02-12 | 2025-05-13 | 江苏惠利生物科技有限公司 | 一种离子交换树脂制备高纯度α-酮戊二酸钙的方法 |
Family Cites Families (71)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2776926A (en) | 1955-08-04 | 1957-01-08 | Eugene S Sharpe | Preparation of alpha-ketoglutaric acid by serratia marcescens |
| US2917528A (en) | 1956-08-24 | 1959-12-15 | Victor Chemical Works | Alkanolaminealkanephosphonic acids and salts thereof |
| US2841616A (en) * | 1956-10-30 | 1958-07-01 | Campbell Soup Co | Process for the recovery of alpha-ketoglutaric acid |
| US3875304A (en) | 1970-04-24 | 1975-04-01 | Schlitz Brewing Co J | Livestock feed composition and method of preparing the same |
| US4045585A (en) | 1976-05-19 | 1977-08-30 | Decel Corporation | Flavored animal food compositions |
| DE3151196A1 (de) * | 1981-12-23 | 1983-06-30 | Kurt Heinz Prof. Dr. 7800 Freiburg Bauer | Verfahren zur herstellung von gut loeslichen 5-aminosalicylsaeure-arzneimittelzubereitungen |
| US6451341B1 (en) | 1990-02-05 | 2002-09-17 | Thomas J. Slaga | Time release formulation of vitamins, minerals and other beneficial supplements |
| US5646187A (en) | 1992-05-20 | 1997-07-08 | Ab Erik Vinnars | Use of alpha-ketoglutarate |
| US6306430B1 (en) | 1998-04-16 | 2001-10-23 | The Iams Company | Process for decreasing adiposity using vitamin a as a dietary supplement |
| US6905707B2 (en) | 1998-05-28 | 2005-06-14 | Medical Research Institute | Controlled release arginine alpha ketoglutarate |
| CO5140079A1 (es) | 1998-10-14 | 2002-03-22 | Novartis Ag | Composicion farmaceutica de liberacion sostenida y metodo para liberar un agente farmaceuticamente activo de liberacion sostenida y metodo para liberar un agente far- maceuticamente activo |
| US6649654B1 (en) | 1999-11-23 | 2003-11-18 | The Regents Of The University Of California | Methods for identifying and using IKK inhibitors |
| JP4169596B2 (ja) | 2000-12-20 | 2008-10-22 | アルコン、インコーポレイテッド | 白内障を液化破壊により取り除くための溶液 |
| JP5049589B2 (ja) * | 2003-05-07 | 2012-10-17 | オステオロジックス エイ／エス | ストロンチウム塩含有の放出制御組成物 |
| US7589235B2 (en) * | 2004-05-06 | 2009-09-15 | Osteologix, A/S | High yield and rapid synthesis methods for producing metallo-organic salts |
| PL368572A1 (en) | 2004-06-17 | 2005-12-27 | Sgp & Sons Ab | Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections |
| EP1778616A1 (en) | 2004-08-09 | 2007-05-02 | Cancer Research Technology Limited | Alpha-ketoglutarates and their use as therapeutic agents |
| AU2005316295B2 (en) | 2004-12-17 | 2012-03-22 | Alan B. Cash | Method for extending lifespan and delaying the onset of age-related disease |
| US20060234250A1 (en) | 2005-04-15 | 2006-10-19 | Powers Ralph W Iii | Methods of screening and compositions for life span modulators |
| WO2007001883A2 (en) | 2005-06-20 | 2007-01-04 | Accera, Inc. | Method to reduce oxidative damage and improve mitochondrial efficiency |
| CA2628265A1 (en) | 2005-11-08 | 2007-05-18 | Multi Formulations Ltd. | The use of compositions comprising ketoacids and amino acids for increasing muscle mass and muscle performance |
| US8367121B2 (en) | 2005-11-23 | 2013-02-05 | Florida A & M University | Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease |
| PL379512A1 (pl) | 2006-04-21 | 2007-10-29 | Sgp & Sons Ab | Nowe metody i ich zastosowanie |
| PL226695B1 (pl) | 2006-07-03 | 2017-08-31 | Danuta Kruszewska | Środek do zastosowania w zapobieganiu i/lub hamowaniu kolonizacji Helicobacter pylori, zastosowanie soli kwasu alfa‑ketoglutarowego z metalami alkalicznymi i ziem alkalicznych do wytwarzania środka leczniczego oraz dodatku do żywności do zapobiegania i/lub hamowania kolonizacji Helicobacter pylori |
| EP2626077A3 (en) | 2007-03-19 | 2013-11-20 | Metaproteomics, LLC | Compositions for promoting bone and joint health |
| CA2691746C (en) | 2007-07-02 | 2016-02-02 | Entress Ab | Use of alpha-ketoglutarate in the treatment of hypertension |
| EP2033623A1 (en) | 2007-09-07 | 2009-03-11 | Cutech S.R.L. | Compositions comprising ornithine ketoglutarate (OKG) |
| JP5406643B2 (ja) | 2008-09-22 | 2014-02-05 | 日本合成化学工業株式会社 | α−オキソカルボン酸の金属塩の製造方法 |
| CN101759553A (zh) | 2008-11-21 | 2010-06-30 | 扬子江药业集团北京海燕药业有限公司 | α-酮酸钙的制备方法 |
| DE102009016119A1 (de) | 2009-04-03 | 2010-10-14 | Evonik Degussa Gmbh | Nahrungsergänzungsmittel enthaltend alpha-Ketosäuren zur Unterstützung der Diabetestherapie |
| KR20130128018A (ko) | 2009-04-10 | 2013-11-25 | 하이얀 치 | 새로운 노화 방지 물질 및 그 확인 방법 |
| EA023913B1 (ru) | 2009-05-11 | 2016-07-29 | БЕРГ ФАРМА ЭлЭлСи | Способы лечения метаболических нарушений, использующие эпиметаболические переключатели, многоаспектные внутриклеточные молекулы или факторы влияния |
| US20100303968A1 (en) | 2009-05-28 | 2010-12-02 | Gregory Dean Sunvold | Pet Food in the Form of a Coated Kibble |
| AU2010258356B2 (en) | 2009-06-12 | 2017-01-19 | Generex Pharmaceuticals, Inc. | Compositions and methods for prevention and treatment of brain diseases and conditions |
| ES2600909T3 (es) | 2009-06-30 | 2017-02-13 | Derman Biomedicine Co. Ltd. | Composiciones que contienen berberina o análogos de la misma para tratar rosácea o trastornos de la piel relacionados con enrojecimiento de la cara |
| US9283257B2 (en) | 2009-11-12 | 2016-03-15 | Nox Technologies, Inc. | Compositions comprising solanum tuberosum for lowering cytosolic NADH level to mimic calorie restriction |
| US20140065099A1 (en) | 2011-02-15 | 2014-03-06 | Ecole Polytechnique Federale De Lausanne (Epfl) | Methods of Treating Mitochondrial Dysfunction |
| JP2014519483A (ja) | 2011-04-18 | 2014-08-14 | ネステク ソシエテ アノニム | α−ヒドロキシイソカプロン酸を含有する栄養組成物 |
| US9248185B2 (en) | 2011-06-16 | 2016-02-02 | President And Fellows Of Harvard College | Methods of increasing satellite cell proliferation |
| CN102586347B (zh) * | 2012-03-06 | 2014-04-09 | 江南大学 | 一种两阶段pH控制高产a-酮戊二酸的方法 |
| US9532997B2 (en) | 2012-04-03 | 2017-01-03 | Whitehead Institute For Biomedical Research | Compositions and methods for promoting intestinal stem cell function |
| ITBO20120226A1 (it) | 2012-04-24 | 2013-10-25 | Alfa Wassermann Spa | Composizioni comprendenti ornitina alfa-chetoglutarato, processi per il loro ottenimento e il loro uso. |
| JP6029058B2 (ja) | 2012-09-14 | 2016-11-24 | 国立研究開発法人農業・食品産業技術総合研究機構 | シュウ酸カルシウムを含む氷核活性剤 |
| AU2013318686B2 (en) | 2012-09-19 | 2017-11-30 | Grespo Ab | Compositions for improvement of brain function |
| CN102976927A (zh) * | 2012-12-26 | 2013-03-20 | 天津天成制药有限公司 | α-酮戊二酸钙的制备方法 |
| WO2014103475A1 (ja) | 2012-12-27 | 2014-07-03 | 株式会社林原 | アンチエイジング用皮膚外用組成物及びその製造方法 |
| WO2014116985A1 (en) | 2013-01-25 | 2014-07-31 | Winning The Fight Inc. | Composition for treatment of neurodegenerative disease |
| US9511057B2 (en) | 2013-03-15 | 2016-12-06 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for treating denervation-induced muscle atrophy |
| MY180761A (en) | 2013-03-19 | 2020-12-08 | Univ South Florida | Compositions and methods for producing elevated and sustained ketosis |
| US20160263092A1 (en) | 2013-12-19 | 2016-09-15 | Twi Biotechnology, Inc. | Therapeutic uses of berberine formulations |
| WO2015123229A1 (en) | 2014-02-12 | 2015-08-20 | The Regents Of The University Of California | Compositions and methods for treating aging and age-related diseases and symptoms |
| WO2015171723A1 (en) | 2014-05-06 | 2015-11-12 | Research Development Foundation | Methods for treating insulin resistance and for sensitizing patients to glp1 agonist therapy |
| AU2015284409B2 (en) | 2014-06-30 | 2020-06-25 | The Regents Of The University Of California | Ketobutyrate compounds and compositions for treating age-related symptoms and diseases |
| CA3194562C (en) | 2014-07-29 | 2026-03-17 | Shenzhen Hightide Biopharmaceutical, Ltd. | Berberine-ursodeoxycholic salt, method of preparation and application therof |
| WO2016019224A1 (en) | 2014-07-31 | 2016-02-04 | Indiana University Research And Technology Corporation | Antithetical regulation of endothelial ace and ace2 by brg1-foxm1 complex underlies pathological cardiac hypertrophy |
| CN104529755B (zh) * | 2014-12-29 | 2016-01-06 | 精晶药业股份有限公司 | 一种从转化液中分离α-酮戊二酸的方法 |
| WO2016161921A1 (en) | 2015-04-06 | 2016-10-13 | Shenzhen Hightide Biopharmaceutical, Ltd. | Conjugate compounds of ursodeoxycholic, berberine or l-carnitine, and compositions and methods thereof |
| KR20180021784A (ko) | 2015-06-10 | 2018-03-05 | 엘리시움 헬스, 인크. | 피부병의 치료를 위한 니코틴아미드 리보시드 및 프테로스틸벤 조성물 및 방법 |
| US20180193458A1 (en) | 2015-07-08 | 2018-07-12 | Unity Biotechnology, Inc. | Compositions and methods for treating senescence-associated diseases and disorders |
| KR20190080875A (ko) | 2016-09-30 | 2019-07-08 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 모발 성장 자극을 위한 알파-케토부티레이트, 알파-케토글루타레이트, 및 2-하이드록시부티레이트 |
| PL231635B1 (pl) | 2017-01-03 | 2019-03-29 | Politechnika Poznanska | Sposób produkcji kwasu alfa-ketoglutarowego (AKG) z jednoskładnikowych roztworów wodnych |
| MX2017004010A (es) | 2017-03-27 | 2018-02-09 | Antonio Hernandez Miramontes Jorge | Mezcla de oxalacetato, alfacetoglutarato, ácido tartánico y sales de lactato de calcio y sodio, para tratar pacientes con insuficiencia renal crónica. |
| WO2018200736A2 (en) | 2017-04-25 | 2018-11-01 | The Buck Institute For Research On Aging | Formulations for extending lifespan and healthspan |
| US20200253907A1 (en) | 2017-08-21 | 2020-08-13 | The Regents Of The University Of California | Compositions and Methods for Treating Neurodegenerative Diseases |
| US11802103B2 (en) | 2018-09-25 | 2023-10-31 | Ponce De Leon Health Designated Activity Company | Process of making calcium alpha-ketoglutarate |
| WO2020086733A1 (en) | 2018-10-24 | 2020-04-30 | Ponce De Leon Health Designated Activity Company | Nicotinamide riboside compositions for healthspan extension |
| CA3142781A1 (en) | 2019-06-10 | 2020-12-17 | Buck Institute For Research On Aging | Methods and compositions for altering senescence associated secretory phenotype |
| EP3980001B1 (en) | 2019-06-10 | 2025-08-27 | Ponce de Leon Health Designated Activity Company | Sustained-release compositions of alpha-ketoglutarate |
| US20230255912A1 (en) | 2020-07-02 | 2023-08-17 | Ponce De Leon Health Designated Activity Company | Compositions and methods for treating crp-mediated diseases |
| CN112941116B (zh) * | 2021-01-04 | 2022-12-02 | 上海朴颐化学科技有限公司 | 一种酶法制备α-酮戊二酸钙的方法 |
| CN115974679A (zh) * | 2022-12-20 | 2023-04-18 | 绍兴市精益生物化工有限公司 | α-酮戊二酸钙盐制备方法 |
-
2019
- 2019-09-23 US US17/277,752 patent/US11802103B2/en active Active
- 2019-09-23 SG SG11202102204PA patent/SG11202102204PA/en unknown
- 2019-09-23 IL IL281761A patent/IL281761B2/en unknown
- 2019-09-23 JP JP2021540377A patent/JP7499259B2/ja active Active
- 2019-09-23 CN CN201980073655.2A patent/CN112955139B/zh active Active
- 2019-09-23 KR KR1020217010402A patent/KR102833111B1/ko active Active
- 2019-09-23 MX MX2021003482A patent/MX2021003482A/es unknown
- 2019-09-23 WO PCT/US2019/052498 patent/WO2020068705A1/en not_active Ceased
- 2019-09-23 AU AU2019350699A patent/AU2019350699B2/en active Active
- 2019-09-23 CA CA3112205A patent/CA3112205A1/en active Pending
- 2019-09-23 EP EP19866432.8A patent/EP3856166A4/en active Pending
- 2019-09-23 MY MYPI2021001576A patent/MY203278A/en unknown
- 2019-09-23 PE PE2021000354A patent/PE20211816A1/es unknown
- 2019-09-23 BR BR112021005668-8A patent/BR112021005668A2/pt unknown
- 2019-09-25 TW TW108134655A patent/TWI863930B/zh active
-
2021
- 2021-02-26 PH PH12021550403A patent/PH12021550403A1/en unknown
- 2021-03-24 CL CL2021000728A patent/CL2021000728A1/es unknown
- 2021-04-11 CO CONC2021/0004529A patent/CO2021004529A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11202102204PA (en) | 2021-04-29 |
| MX2021003482A (es) | 2021-06-18 |
| AU2019350699B2 (en) | 2024-05-23 |
| CL2021000728A1 (es) | 2021-10-22 |
| US20210371368A1 (en) | 2021-12-02 |
| TW202024013A (zh) | 2020-07-01 |
| CN112955139A (zh) | 2021-06-11 |
| TWI863930B (zh) | 2024-12-01 |
| US11802103B2 (en) | 2023-10-31 |
| AU2019350699A1 (en) | 2021-04-08 |
| MY203278A (en) | 2024-06-21 |
| CA3112205A1 (en) | 2020-04-02 |
| IL281761B1 (en) | 2025-05-01 |
| BR112021005668A2 (pt) | 2021-06-22 |
| JP2022502489A (ja) | 2022-01-11 |
| IL281761B2 (en) | 2025-09-01 |
| EP3856166A1 (en) | 2021-08-04 |
| EP3856166A4 (en) | 2022-06-22 |
| CN112955139B (zh) | 2025-04-18 |
| KR20210065120A (ko) | 2021-06-03 |
| KR102833111B1 (ko) | 2025-07-10 |
| PH12021550403A1 (en) | 2021-10-04 |
| JP7499259B2 (ja) | 2024-06-13 |
| CO2021004529A2 (es) | 2021-04-30 |
| WO2020068705A1 (en) | 2020-04-02 |
| IL281761A (en) | 2021-05-31 |
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