PE20171321A1 - Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion - Google Patents

Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion

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Publication number
PE20171321A1
PE20171321A1 PE2017001077A PE2017001077A PE20171321A1 PE 20171321 A1 PE20171321 A1 PE 20171321A1 PE 2017001077 A PE2017001077 A PE 2017001077A PE 2017001077 A PE2017001077 A PE 2017001077A PE 20171321 A1 PE20171321 A1 PE 20171321A1
Authority
PE
Peru
Prior art keywords
treatment
modifier
retention
gases
prevents
Prior art date
Application number
PE2017001077A
Other languages
English (en)
Inventor
Roberto Bernardo Escudero
Vilboeuf John Claude Savoir
Original Assignee
Posi Visionary Solutions Llp
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46084557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20171321(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Posi Visionary Solutions Llp filed Critical Posi Visionary Solutions Llp
Publication of PE20171321A1 publication Critical patent/PE20171321A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
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    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
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    • A61K38/482—Serine endopeptidases (3.4.21)
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • C12Y—ENZYMES
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Referido un metodo de preparacion de una formulacion farmaceutica que comprende (1) mezclar y tamizar trimebutina, dimeticona, alfa-D-galactosidasa, y una solucion aglutinante para obtener una mezcla; y (2) moler, secar, y tamizar la mezcla para obtener una mezcla molida, seca y tamizada, en donde la formulacion farmaceutica es una tableta, tableta recubierta o capsula. Tambien se refiere a una formulacion farmaceutica en donde los ingredientes activos de la composicion consisten de trimebutina, simeticona, y alfa-D-galactosidasa, siendo util en el tratamiento del sindrome de intestino irritable.
PE2017001077A 2010-11-16 2011-11-15 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion PE20171321A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MX2010012479A MX2010012479A (es) 2010-11-16 2010-11-16 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion.

Publications (1)

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PE20171321A1 true PE20171321A1 (es) 2017-09-07

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PE2013001060A PE20140380A1 (es) 2010-11-16 2011-11-15 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion
PE2017001077A PE20171321A1 (es) 2010-11-16 2011-11-15 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion

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PE2013001060A PE20140380A1 (es) 2010-11-16 2011-11-15 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion

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US (2) US20130344145A1 (es)
EP (1) EP2641598B1 (es)
JP (2) JP6166179B2 (es)
KR (1) KR101958031B1 (es)
CN (1) CN103429237A (es)
AR (1) AR083888A1 (es)
AU (1) AU2011329916B2 (es)
BR (1) BR112013012100B8 (es)
CA (1) CA2818129C (es)
CL (1) CL2013001331A1 (es)
CO (1) CO6731095A2 (es)
CR (1) CR20130219A (es)
DO (1) DOP2013000107A (es)
EC (1) ECSP13012642A (es)
ES (1) ES2685784T3 (es)
GT (1) GT201300119A (es)
MA (1) MA34729B1 (es)
MX (1) MX2010012479A (es)
PE (2) PE20140380A1 (es)
PL (1) PL2641598T3 (es)
PT (1) PT2641598T (es)
RS (1) RS57857B1 (es)
RU (1) RU2581920C2 (es)
TR (1) TR201812643T4 (es)
UA (1) UA111480C2 (es)
UY (1) UY33733A (es)
WO (1) WO2012067481A2 (es)
ZA (1) ZA201303518B (es)

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JP6385642B2 (ja) * 2013-02-28 2018-09-05 小林製薬株式会社 内服用組成物
US9402885B2 (en) * 2013-07-15 2016-08-02 Alfa Wassermann S.P.A. Method of treating GERD with alpha and beta galactosidases
US10993996B2 (en) * 2013-08-09 2021-05-04 Allergan Pharmaceuticals International Limited Digestive enzyme composition suitable for enteral administration
WO2016114734A1 (en) * 2015-01-16 2016-07-21 Biofarma Ilaç Sanayi Ve Ticaret A. Ş. Pharmaceutical formulation of trimebutine maleate and simethicone comprising acidifying agent
IT201700006355A1 (it) * 2017-01-20 2018-07-20 Neilos S R L Composizione per il trattamento dei disturbi gastrointestinali
CN109200278A (zh) * 2018-10-08 2019-01-15 毛玉坤 腔镜去粘液消泡剂及其制备方法

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