BR112013012100B8 - Composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula para uso no tratamento de distúrbios intestinais, e, processo para preparar uma composição farmacêutica - Google Patents

Composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula para uso no tratamento de distúrbios intestinais, e, processo para preparar uma composição farmacêutica

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Publication number
BR112013012100B8
BR112013012100B8 BR112013012100A BR112013012100A BR112013012100B8 BR 112013012100 B8 BR112013012100 B8 BR 112013012100B8 BR 112013012100 A BR112013012100 A BR 112013012100A BR 112013012100 A BR112013012100 A BR 112013012100A BR 112013012100 B8 BR112013012100 B8 BR 112013012100B8
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BR
Brazil
Prior art keywords
pharmaceutical composition
tablet
agent
oral administration
intestinal
Prior art date
Application number
BR112013012100A
Other languages
English (en)
Other versions
BR112013012100B1 (pt
BR112013012100A2 (pt
Inventor
Claude Savoir Vilboeuf John
Bernardo Escudero Roberto
Original Assignee
Posi Visionary Solutions Llp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46084557&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013012100(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Posi Visionary Solutions Llp filed Critical Posi Visionary Solutions Llp
Publication of BR112013012100A2 publication Critical patent/BR112013012100A2/pt
Publication of BR112013012100B1 publication Critical patent/BR112013012100B1/pt
Publication of BR112013012100B8 publication Critical patent/BR112013012100B8/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
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    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4826—Trypsin (3.4.21.4) Chymotrypsin (3.4.21.1)
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    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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    • A—HUMAN NECESSITIES
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    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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    • C—CHEMISTRY; METALLURGY
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    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01022—Alpha-galactosidase (3.2.1.22)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pretreatment Of Seeds And Plants (AREA)

Abstract

composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula para prevenção ou tratamento de distúrbios intestinais, processo para preparar a composição ou formulação farmacêutica e uso de uma composição ou formulação farmacêutica uma composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula na prevenção ou tratamento de distúrbios intestinais tais como a síndrome do intestino irritável, também conhecida como síndrome de cólon irritável, à base de um modificador da motilidade intestinal, de um agente que previne a retenção de gases, de enzimas digestivas, de um agente aglutinante, de um agente diluente, de um agente adsorvente, de um agente desintegrante, de um agente lubrificante e de um agente deslizante, efetiva para normalizar o trânsito intestinal, para conseguir uma atividade analgésica, para conseguir uma atividade antiespasmódica e para reduzir os sintomas relacionados com o gás intestinal tais como, a distensão, a dor abdominal e a flatulência.
BR112013012100A 2010-11-16 2011-11-15 Composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula para uso no tratamento de distúrbios intestinais, e, processo para preparar uma composição farmacêutica BR112013012100B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
MXMX/A/2010/012479 2010-11-16
MX2010012479A MX2010012479A (es) 2010-11-16 2010-11-16 Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion.
PCT/MX2011/000138 WO2012067481A2 (es) 2010-11-16 2011-11-15 Composición farmacéutica de administración oral para el tratamiento del síndrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retención de gases y enzimas digestivas y proceso para su preparación

Publications (3)

Publication Number Publication Date
BR112013012100A2 BR112013012100A2 (pt) 2016-08-16
BR112013012100B1 BR112013012100B1 (pt) 2021-11-09
BR112013012100B8 true BR112013012100B8 (pt) 2022-01-11

Family

ID=46084557

Family Applications (1)

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BR112013012100A BR112013012100B8 (pt) 2010-11-16 2011-11-15 Composição ou formulação farmacêutica adaptada para administração oral em forma de comprimido, comprimido revestido ou cápsula para uso no tratamento de distúrbios intestinais, e, processo para preparar uma composição farmacêutica

Country Status (28)

Country Link
US (2) US20130344145A1 (pt)
EP (1) EP2641598B1 (pt)
JP (2) JP6166179B2 (pt)
KR (1) KR101958031B1 (pt)
CN (1) CN103429237A (pt)
AR (1) AR083888A1 (pt)
AU (1) AU2011329916B2 (pt)
BR (1) BR112013012100B8 (pt)
CA (1) CA2818129C (pt)
CL (1) CL2013001331A1 (pt)
CO (1) CO6731095A2 (pt)
CR (1) CR20130219A (pt)
DO (1) DOP2013000107A (pt)
EC (1) ECSP13012642A (pt)
ES (1) ES2685784T3 (pt)
GT (1) GT201300119A (pt)
MA (1) MA34729B1 (pt)
MX (1) MX2010012479A (pt)
PE (2) PE20171321A1 (pt)
PL (1) PL2641598T3 (pt)
PT (1) PT2641598T (pt)
RS (1) RS57857B1 (pt)
RU (1) RU2581920C2 (pt)
TR (1) TR201812643T4 (pt)
UA (1) UA111480C2 (pt)
UY (1) UY33733A (pt)
WO (1) WO2012067481A2 (pt)
ZA (1) ZA201303518B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6385642B2 (ja) * 2013-02-28 2018-09-05 小林製薬株式会社 内服用組成物
US9402885B2 (en) * 2013-07-15 2016-08-02 Alfa Wassermann S.P.A. Method of treating GERD with alpha and beta galactosidases
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