PE20110386A1 - Patron de transcripcion sanguinea de la infeccion por mycobacterium tuberculosis - Google Patents

Patron de transcripcion sanguinea de la infeccion por mycobacterium tuberculosis

Info

Publication number
PE20110386A1
PE20110386A1 PE2010001182A PE2010001182A PE20110386A1 PE 20110386 A1 PE20110386 A1 PE 20110386A1 PE 2010001182 A PE2010001182 A PE 2010001182A PE 2010001182 A PE2010001182 A PE 2010001182A PE 20110386 A1 PE20110386 A1 PE 20110386A1
Authority
PE
Peru
Prior art keywords
data
modules
infection
mycobacterium tuberculosis
tuberculosis infection
Prior art date
Application number
PE2010001182A
Other languages
English (en)
Inventor
Jacques F Banchereau
Damien Chaussabel
Anne O'garra
Matthew Berry
Onn Min Kon
Original Assignee
Baylor Res Inst
Nat Inst For Medical Res
Imp College Healthcare Nhs Trust
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor Res Inst, Nat Inst For Medical Res, Imp College Healthcare Nhs Trust filed Critical Baylor Res Inst
Publication of PE20110386A1 publication Critical patent/PE20110386A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

REFERIDA A UN METODO PARA DIFERENCIAR UNA INFECCION POR MYCOBACTERIUM TUBERCULOSIS ACTIVA DE UNA LATENTE EN UN PACIENTE, QUE COMPRENDE OBTENER UN CONJUNTO DE DATOS DE EXPRESION GENICA DE UNA MUESTRA DE SANGRE ENTERA DE UN PACIENTE Y DETERMINAR LA EXPRESION DIFERENCIAL DE UNO O MAS MODULOS DE EXPRESION GENICA QUE DISTINGUEN ENTRE INDIVIDUOS INFECTADOS Y NO INFECTADOS, DONDE EL CONJUNTO DE DATOS DEMUESTRA UN CAMBIO AGREGADO EN LOS NIVELES DE POLINUCLEOTIDOS EN UNO O MAS MODULOS DE EXPRESION GENICA DE TRANSCRIPCION PARA INDIVIDUOS INFECTADOS. EL MODULO COMPRENDE UN CONJUNTO DE DATOS DE LOS GENES EN LOS MODULOS M1.2, M1.3, M1.4, M1.5, M1.8, M2.1, M2.4, M2.8, M3.1, M3.2, M3.3, M3.4, M3.6, M3.7, M3.8 O M3.9 PARA DETECTAR LA INFECCION PULMONAR ACTIVA Y PARA DETECTAR UNA INFECCION LATENTE, EL MODULO COMPRENDE UN CONJUNTO DE DATOS DE LOS GENES EN LOS MODULOS M1.5, M2.1, M2.6, M2.10, M3.2 O M3.3
PE2010001182A 2008-06-25 2009-06-25 Patron de transcripcion sanguinea de la infeccion por mycobacterium tuberculosis PE20110386A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7572808P 2008-06-25 2008-06-25

Publications (1)

Publication Number Publication Date
PE20110386A1 true PE20110386A1 (es) 2011-07-03

Family

ID=41445303

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2010001182A PE20110386A1 (es) 2008-06-25 2009-06-25 Patron de transcripcion sanguinea de la infeccion por mycobacterium tuberculosis

Country Status (17)

Country Link
US (1) US20110196614A1 (es)
EP (1) EP2300823A4 (es)
JP (1) JP2011526152A (es)
KR (1) KR20110036590A (es)
CN (1) CN102150043A (es)
AP (1) AP2011005546A0 (es)
AU (1) AU2009262112A1 (es)
CA (1) CA2729000A1 (es)
EA (1) EA201170088A1 (es)
IL (1) IL210121A0 (es)
MX (1) MX2010014556A (es)
NZ (1) NZ590341A (es)
PE (1) PE20110386A1 (es)
SG (1) SG182951A1 (es)
TW (1) TW201022492A (es)
WO (1) WO2009158521A2 (es)
ZA (1) ZA201009307B (es)

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Also Published As

Publication number Publication date
SG182951A1 (en) 2012-08-30
US20110196614A1 (en) 2011-08-11
EP2300823A2 (en) 2011-03-30
AP2011005546A0 (en) 2011-02-28
NZ590341A (en) 2012-07-27
CN102150043A (zh) 2011-08-10
EA201170088A1 (ru) 2011-10-31
TW201022492A (en) 2010-06-16
EP2300823A4 (en) 2012-03-14
CA2729000A1 (en) 2009-12-30
MX2010014556A (es) 2011-07-28
JP2011526152A (ja) 2011-10-06
WO2009158521A3 (en) 2010-05-14
WO2009158521A2 (en) 2009-12-30
IL210121A0 (en) 2011-02-28
ZA201009307B (en) 2012-10-31
KR20110036590A (ko) 2011-04-07
AU2009262112A1 (en) 2009-12-30

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