PT2128612E - Monitorização imunológica baseada em ip-10 - Google Patents

Monitorização imunológica baseada em ip-10 Download PDF

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Publication number
PT2128612E
PT2128612E PT09170735T PT09170735T PT2128612E PT 2128612 E PT2128612 E PT 2128612E PT 09170735 T PT09170735 T PT 09170735T PT 09170735 T PT09170735 T PT 09170735T PT 2128612 E PT2128612 E PT 2128612E
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PT
Portugal
Prior art keywords
cmi
present
invention further
immunological monitoring
relates
Prior art date
Application number
PT09170735T
Other languages
English (en)
Inventor
Jesper Eugen-Olsen
Morten Ruhwald
Pernille Ravn
Original Assignee
Hvidovre Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hvidovre Hospital filed Critical Hvidovre Hospital
Publication of PT2128612E publication Critical patent/PT2128612E/pt

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56927—Chlamydia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/32—Mycobacterium
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/02—Hepadnaviridae, e.g. hepatitis B virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/295—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Chlamydiales (o)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/44—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from protozoa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Toxicology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT09170735T 2006-09-05 2007-09-05 Monitorização imunológica baseada em ip-10 PT2128612E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200601145 2006-09-05
DKPA200700262 2007-02-20

Publications (1)

Publication Number Publication Date
PT2128612E true PT2128612E (pt) 2011-07-06

Family

ID=38716188

Family Applications (1)

Application Number Title Priority Date Filing Date
PT09170735T PT2128612E (pt) 2006-09-05 2007-09-05 Monitorização imunológica baseada em ip-10

Country Status (17)

Country Link
US (2) US8026076B2 (pt)
EP (4) EP2261658B1 (pt)
JP (1) JP5805368B2 (pt)
KR (1) KR101248491B1 (pt)
CN (1) CN101523217B (pt)
AT (1) ATE504000T1 (pt)
AU (1) AU2007294293B2 (pt)
BR (1) BRPI0714744B8 (pt)
CA (1) CA2662429C (pt)
DE (1) DE602007013620D1 (pt)
DK (2) DK2261658T3 (pt)
EA (1) EA020412B1 (pt)
IN (1) IN2015DN03125A (pt)
PL (1) PL2128612T3 (pt)
PT (1) PT2128612E (pt)
WO (1) WO2008028489A2 (pt)
ZA (1) ZA200902297B (pt)

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WO2010009494A1 (en) * 2008-07-25 2010-01-28 Cellestis Limited A diagnostic method
CN102246040B (zh) * 2008-12-15 2014-11-05 安特鲁姆生物技术（私人）有限公司 用于诊断结核病的方法和装置
GB0906215D0 (en) 2009-04-09 2009-05-20 Lalvani Ajit Diagnostic test
ES2413437T3 (es) * 2010-03-10 2013-07-16 Institut Pasteur HMGB1 y anticuerpos anti-HMGB1 en pacientes infectados por VIH especialmente con trastornos neurológicos
US20130078657A1 (en) * 2010-05-04 2013-03-28 Hvidovre Hospital Hyperthermia augmented in-vitro immune recognition
US20140087363A1 (en) * 2010-12-09 2014-03-27 Hvidovre Hospital Method for generating, storing, transporting, eluting and detecting clinical relevant information in plasma using filter paper
WO2012139591A1 (en) 2011-04-13 2012-10-18 Hvidovre Hospital Monitoring liver fibrosis in a hepatitis c infected patient
CN103619880A (zh) * 2011-04-29 2014-03-05 百时美施贵宝公司 Ip-10抗体剂量递增方法
CN103122033B (zh) * 2011-11-21 2015-08-19 厦门大学 一种嵌合重组抗原及其用途
US20140342936A1 (en) * 2011-12-15 2014-11-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and kits for diagnosing latent tuberculosis infection
WO2013168876A1 (ko) 2012-05-11 2013-11-14 가톨릭대학교 산학협력단 이식 후 면역 상태를 모니터링 하는 키트 및 이를 이용한 면역 상태의 모니터링 방법
JP6102438B2 (ja) 2012-05-30 2017-03-29 三菱化学株式会社 軸受部材、端部部材、感光体ドラムユニット、プロセスカートリッジ、及び軸受部材の製造方法
JP6020237B2 (ja) 2013-02-15 2016-11-02 三菱化学株式会社 軸受部材、端部部材、感光体ドラムユニット、及び軸受部材の製造方法
US10449228B2 (en) 2013-09-10 2019-10-22 Immusant, Inc. Dosage of a gluten peptide composition
KR101542510B1 (ko) 2014-01-15 2015-08-18 대한민국 초기 hiv-1 감염자에서 급속한 aids 질환 진행을 예측하기 위한 ip-10의 용도
CN106461675B (zh) * 2014-02-26 2019-07-12 斯坦陵布什大学 用于诊断肺结核的方法
KR101590324B1 (ko) * 2014-04-24 2016-02-01 연세대학교 산학협력단 향상된 결핵 진단 방법
AU2015249592A1 (en) * 2014-04-24 2016-12-15 Immusant, Inc. Use of Interleukin-2 for diagnosis of Celiac disease
EP3699930B1 (en) 2014-08-14 2024-02-07 MeMed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
KR101748296B1 (ko) 2014-09-04 2017-06-19 연세대학교 산학협력단 마이코박테리움 압세수스 복합체 감염 폐질환 진단용 바이오마커 조성물
WO2016054038A1 (en) 2014-09-29 2016-04-07 Immusant, Inc. Use of hla genetic status to assess or select treatment of celiac disease
EP3221344A2 (en) 2014-11-21 2017-09-27 Immusant Inc. Peptides for use in treatment and diagnosis of type 1 diabetes
CN104897893A (zh) * 2015-06-10 2015-09-09 复旦大学附属华山医院 一种基于结核特异性il-31检测的诊断结核分枝杆菌感染的试剂盒
CN108699583B (zh) 2016-03-03 2022-11-01 米密德诊断学有限公司 用于区分细菌和病毒感染的rna决定子
EP3482200B1 (en) 2016-07-10 2022-05-04 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
EP3482201B1 (en) * 2016-07-10 2022-12-14 Memed Diagnostics Ltd. Early diagnosis of infections
WO2018060998A1 (en) 2016-09-29 2018-04-05 Memed Diagnostics Ltd. Methods of prognosis and treatment
US11353456B2 (en) 2016-09-29 2022-06-07 Memed Diagnostics Ltd. Methods of risk assessment and disease classification for appendicitis
CN108548917B (zh) * 2018-03-01 2021-07-06 广州市雷德生物科技有限公司 一种记忆性免疫细胞的检测体系及其应用
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WO2021255237A1 (en) 2020-06-19 2021-12-23 Mikrogen Gmbh Method of detecting infection with pathogens causing tuberculosis
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WO2022240887A1 (en) * 2021-05-10 2022-11-17 Icahn School Of Medicine At Mount Sinai Methods for detecting and staging cellular viral immune responses

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Also Published As

Publication number Publication date
EP2059816A2 (en) 2009-05-20
DE602007013620D1 (de) 2011-05-12
BRPI0714744B1 (pt) 2018-10-16
US20120015386A1 (en) 2012-01-19
EP2261658A2 (en) 2010-12-15
EP2128612B1 (en) 2011-03-30
US8026076B2 (en) 2011-09-27
CA2662429C (en) 2016-06-28
EP2228651A1 (en) 2010-09-15
CA2662429A1 (en) 2008-03-13
BRPI0714744A8 (pt) 2016-04-05
AU2007294293A1 (en) 2008-03-13
BRPI0714744A2 (pt) 2013-05-07
EA200970246A1 (ru) 2009-10-30
ZA200902297B (en) 2015-10-28
KR101248491B1 (ko) 2013-04-03
EP2261658A3 (en) 2011-05-11
KR20090074026A (ko) 2009-07-03
WO2008028489A3 (en) 2008-05-15
EP2128612A3 (en) 2009-12-09
IN2015DN03125A (pt) 2015-10-02
DK2128612T3 (da) 2011-07-18
WO2008028489A2 (en) 2008-03-13
CN101523217B (zh) 2014-03-19
JP5805368B2 (ja) 2015-11-04
EP2128612A2 (en) 2009-12-02
EA020412B1 (ru) 2014-11-28
US20100086950A1 (en) 2010-04-08
EP2261658B1 (en) 2015-01-28
JP2010502200A (ja) 2010-01-28
PL2128612T3 (pl) 2011-09-30
BRPI0714744B8 (pt) 2021-07-27
ATE504000T1 (de) 2011-04-15
CN101523217A (zh) 2009-09-02
AU2007294293B2 (en) 2013-06-27
DK2261658T3 (en) 2015-04-27

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