PE20080351A1 - Compuesto peptidico antimicrobiano a partir de bacillus clausii su preparacion y composicion farmaceutica - Google Patents

Compuesto peptidico antimicrobiano a partir de bacillus clausii su preparacion y composicion farmaceutica

Info

Publication number
PE20080351A1
PE20080351A1 PE2007000409A PE2007000409A PE20080351A1 PE 20080351 A1 PE20080351 A1 PE 20080351A1 PE 2007000409 A PE2007000409 A PE 2007000409A PE 2007000409 A PE2007000409 A PE 2007000409A PE 20080351 A1 PE20080351 A1 PE 20080351A1
Authority
PE
Peru
Prior art keywords
ala
phe
dhb
gly
pharmaceutical composition
Prior art date
Application number
PE2007000409A
Other languages
English (en)
Inventor
Philippe Bressollier
Maria Attilia Brugo
Pascale Robineau
Jean-Marie Schmitter
Maria Camino Urdaci
Bernard Verneuil
Original Assignee
Sanofi Aventis Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38481126&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20080351(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanofi Aventis Spa filed Critical Sanofi Aventis Spa
Publication of PE20080351A1 publication Critical patent/PE20080351A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Abstract

SE REFIERE A UN COMPUESTO PEPTIDICO DE ACTIVIDAD ANTIMICROBIANA, OBTENIDA A PARTIR DE UN CULTIVO DE BACILLUS CLAUSII, EN DONDE DICHO COMPUESTO ES UN LANTIBIOTICO QUE TIENE UNA MASA MOLECULAR DE 2107,7 Da; PRESENTA PUENTES DE LANTOINA Y AMINOACIDOS VARIABLES; Y COMPRENDE LA SECUENCIA AMINOACIDICA: Phe-Dhb-Ala-Val-Dha-Phe-Ala-Abu-Pro-Gly-Ala-Gly-Glu-Dhb-Gly-Ala-Phe-Asn-Ala-Phe-Ala, EN DONDE Dhb ES UN DIDESHIDROAMINOBUTIRATO; Dha ES UN DIDESHIDROALANINA Y Abu ES UN AMINOBUTIRATO, SUS RESIDUOS AMINOACIDICOS SON ENANTIOMEROS (L) Y PRESENTA ACTIVIDAD FRENTE A GRAM POSITIVOS TAL COMO: S.AUREUS, ENTEROCOCCUS, CLOSTRIDIUM, ENTRE OTROS. TAMBIEN SE REFIERE A UN PROCEDIMIENTO DE PREPARACION Y UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON UTILES EN EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS Y EN EL TRATAMIENTO O PREVENCION DE DISMICROBISMO INTESTINAL Y/O DISVITAMINOSIS ENDOGENA, PARA LA RECUPERACION DE LA FLORA INTESTINAL
PE2007000409A 2006-04-06 2007-04-04 Compuesto peptidico antimicrobiano a partir de bacillus clausii su preparacion y composicion farmaceutica PE20080351A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000678A ITMI20060678A1 (it) 2006-04-06 2006-04-06 Composto peptidico ad attivita' b iologica sua preparazione e sue applicazioni

Publications (1)

Publication Number Publication Date
PE20080351A1 true PE20080351A1 (es) 2008-06-12

Family

ID=38481126

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2007000409A PE20080351A1 (es) 2006-04-06 2007-04-04 Compuesto peptidico antimicrobiano a partir de bacillus clausii su preparacion y composicion farmaceutica

Country Status (35)

Country Link
US (1) US8691773B2 (es)
EP (1) EP2013234B1 (es)
JP (1) JP5196407B2 (es)
KR (1) KR101556414B1 (es)
CN (1) CN101415725B (es)
AR (1) AR060350A1 (es)
AT (1) ATE535540T1 (es)
AU (1) AU2007232210B2 (es)
BR (1) BRPI0710846A2 (es)
CA (1) CA2646892C (es)
CL (1) CL2007000955A1 (es)
CR (1) CR10302A (es)
DO (1) DOP2007000065A (es)
EA (1) EA015943B1 (es)
EC (1) ECSP088785A (es)
GE (1) GEP20115282B (es)
GT (1) GT200800204A (es)
HK (1) HK1128480A1 (es)
HN (1) HN2008001516A (es)
IL (1) IL194325A (es)
IT (1) ITMI20060678A1 (es)
JO (1) JO2739B1 (es)
MA (1) MA30465B1 (es)
ME (2) MEP31908A (es)
MX (1) MX2008012730A (es)
MY (1) MY151092A (es)
NI (1) NI200800265A (es)
NO (1) NO341813B1 (es)
NZ (1) NZ571477A (es)
PE (1) PE20080351A1 (es)
TN (1) TNSN08377A1 (es)
TW (1) TWI380994B (es)
UA (1) UA92793C2 (es)
WO (1) WO2007113691A2 (es)
ZA (1) ZA200808328B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU92906B1 (en) 2015-12-14 2017-06-20 Luxembourg Inst Science & Tech List Method for enzymatically modifying the tri-dimensional structure of a protein
CN106366168B (zh) * 2016-08-26 2020-09-15 上海交通大学 羊毛硫肽类抗菌肽及其脱氢衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69629691T2 (de) * 1995-06-23 2004-02-26 Ambi, Inc. Verfahren zur kontrolle von antibiotikaresistenten grampositiven bakterien und behandlung von infektionen
US5985823A (en) * 1997-06-09 1999-11-16 Ambi Inc. Method for the treatment of diarrheal disease and for eliminating particular bacterial populations from the colon
US5932469A (en) * 1997-06-10 1999-08-03 University Of Florida Antimicrobial polypeptide, nucleic acid, and methods of use
ITMI20021800A1 (it) * 2002-08-07 2004-02-08 Proge Farm Srl Composizione farmaceutica e/o nutraceutica comprendente una associazione di microorganismi probiotici non sporigeni e spore di bacillus subtilis e/o clausii.
CA2404356A1 (en) * 2002-09-18 2004-03-18 Canadian Inovatech Inc. Gram-positive antibacterial composition and method for use
US7354888B2 (en) * 2004-11-10 2008-04-08 Danisco A/S Antibacterial composition and methods thereof comprising a ternary builder mixture

Also Published As

Publication number Publication date
US8691773B2 (en) 2014-04-08
ZA200808328B (en) 2009-12-30
JO2739B1 (en) 2014-03-15
NZ571477A (en) 2011-09-30
US20090312262A1 (en) 2009-12-17
CA2646892A1 (en) 2007-10-11
NO20084671L (no) 2008-11-05
NO341813B1 (no) 2018-01-29
CL2007000955A1 (es) 2008-01-18
MX2008012730A (es) 2008-11-27
DOP2007000065A (es) 2007-11-30
JP2009532456A (ja) 2009-09-10
EP2013234B1 (en) 2011-11-30
MY151092A (en) 2014-04-15
CR10302A (es) 2009-01-27
ATE535540T1 (de) 2011-12-15
GEP20115282B (en) 2011-09-12
ECSP088785A (es) 2009-01-30
AR060350A1 (es) 2008-06-11
UA92793C2 (ru) 2010-12-10
KR20080110774A (ko) 2008-12-19
HK1128480A1 (en) 2009-10-30
TNSN08377A1 (en) 2009-12-29
TWI380994B (zh) 2013-01-01
EA015943B1 (ru) 2011-12-30
AU2007232210A1 (en) 2007-10-11
AU2007232210B2 (en) 2012-11-15
CN101415725A (zh) 2009-04-22
EP2013234A2 (en) 2009-01-14
IL194325A0 (en) 2011-08-01
EA200870414A1 (ru) 2009-02-27
TW200806688A (en) 2008-02-01
CN101415725B (zh) 2013-08-14
BRPI0710846A2 (pt) 2011-08-23
IL194325A (en) 2011-09-27
HN2008001516A (es) 2011-02-16
WO2007113691A2 (en) 2007-10-11
JP5196407B2 (ja) 2013-05-15
KR101556414B1 (ko) 2015-10-01
NI200800265A (es) 2011-01-10
MEP31908A (en) 2010-10-10
MA30465B1 (fr) 2009-06-01
ME00194B (me) 2010-10-10
ITMI20060678A1 (it) 2007-10-07
GT200800204A (es) 2010-04-05
WO2007113691A3 (en) 2007-12-27
CA2646892C (en) 2016-01-05

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Legal Events

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FG Grant, registration
FD Application declared void or lapsed