BR0317762A - Peptìdeos inibidores de ace a partir de materiais vegetais - Google Patents
Peptìdeos inibidores de ace a partir de materiais vegetaisInfo
- Publication number
- BR0317762A BR0317762A BR0317762-9A BR0317762A BR0317762A BR 0317762 A BR0317762 A BR 0317762A BR 0317762 A BR0317762 A BR 0317762A BR 0317762 A BR0317762 A BR 0317762A
- Authority
- BR
- Brazil
- Prior art keywords
- ace inhibitor
- inhibitor peptides
- plant materials
- sprinkle
- val
- Prior art date
Links
- 239000005541 ACE inhibitor Substances 0.000 title abstract 4
- 229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 239000000463 material Substances 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 235000013312 flour Nutrition 0.000 abstract 2
- RFCVXVPWSPOMFJ-STQMWFEESA-N Phe-Leu Chemical compound CC(C)C[C@@H](C(O)=O)NC(=O)[C@@H](N)CC1=CC=CC=C1 RFCVXVPWSPOMFJ-STQMWFEESA-N 0.000 abstract 1
- NZYNRRGJJVSSTJ-GUBZILKMSA-N Val-Ser-Val Chemical compound CC(C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(O)=O NZYNRRGJJVSSTJ-GUBZILKMSA-N 0.000 abstract 1
- 230000029087 digestion Effects 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 108010073101 phenylalanylleucine Proteins 0.000 abstract 1
- 239000005418 vegetable material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/14—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
- A23J1/142—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds by extracting with organic solvents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/14—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
- A23J1/148—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds by treatment involving enzymes or microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/346—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of vegetable proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/55—Linaceae (Flax family), e.g. Linum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2300/00—Processes
- A23V2300/34—Membrane process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Alternative & Traditional Medicine (AREA)
- Nutrition Science (AREA)
- Zoology (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
"PEPTìDEOS INIBIDORES DE ACE A PARTIR DE MATERIAIS VEGETAIS". A presente invenção refere-se a processos melhorados para a preparação de hidrolisados contendo peptídeo inibidor de ACE a partir de um material de planta tal como uma farinha ou um polvilho de semente. Em uma concretização, a farinha ou polvilho de semente é extraído com um solvente orgânico antes da digestão. Também são proporcionados peptídeos inibidores de ACE Val-Ser-Val e Phe-Leu.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43586602P | 2002-12-24 | 2002-12-24 | |
PCT/CA2003/002020 WO2004057976A1 (en) | 2002-12-24 | 2003-12-24 | Ace inhibitory peptides from plant materials |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0317762A true BR0317762A (pt) | 2005-11-22 |
Family
ID=32682288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0317762-9A BR0317762A (pt) | 2002-12-24 | 2003-12-24 | Peptìdeos inibidores de ace a partir de materiais vegetais |
Country Status (9)
Country | Link |
---|---|
US (1) | US7566690B2 (pt) |
EP (1) | EP1575375A1 (pt) |
JP (1) | JP4538326B2 (pt) |
CN (2) | CN1731934B (pt) |
AU (1) | AU2003289794A1 (pt) |
BR (1) | BR0317762A (pt) |
CA (1) | CA2508219C (pt) |
MX (1) | MXPA05006403A (pt) |
WO (1) | WO2004057976A1 (pt) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2869228B1 (fr) * | 2004-04-21 | 2008-09-05 | Vincience Sa | Utilisation d'un hydrolysat de proteines de cruciferes en tant qu'agent depigmentant dans ou pour une composition cosmetique et/ou pharmaceutique |
JP2006052171A (ja) * | 2004-08-12 | 2006-02-23 | Gunze Ltd | Ace阻害剤 |
WO2006037655A2 (en) * | 2004-10-07 | 2006-04-13 | Nestec S.A. | Bioactive compositions, natural methods of producing them and computational methods for designing natural production processes |
JP5011121B2 (ja) * | 2005-10-24 | 2012-08-29 | ロート製薬株式会社 | コラーゲンおよび/またはヒアルロン酸産生促進用組成物 |
JP4994093B2 (ja) * | 2006-04-13 | 2012-08-08 | ロート製薬株式会社 | 育毛剤 |
CN100456948C (zh) * | 2006-06-30 | 2009-02-04 | 北京三友汇智生物技术有限公司 | 一种燕麦肽及其提取方法 |
EP1967524A1 (en) * | 2007-03-06 | 2008-09-10 | Friesland Brands B.V. | Methods for producing ACE-inhibitory peptides from whey and peptides obtained thereby |
WO2008122138A1 (en) * | 2007-04-05 | 2008-10-16 | Givaudan Sa | Fermented ingredient |
US8211485B2 (en) * | 2007-06-06 | 2012-07-03 | North Carolina A&T State University | Process for preparing hypoallergenic and non-allergenic peanuts (Arachis hypogaea) utilizing an endopeptidase |
US8257753B2 (en) | 2007-07-20 | 2012-09-04 | Isp Investments Inc. | Use of an active principle originating from flax in a composition intended to reinforce the barrier function of the skin and to protect the skin and the appendages against external aggressions |
FR2918893B1 (fr) * | 2007-07-20 | 2012-10-19 | Vincience | Utilisation d'un principe actif issu du lin pour preparer une composition destinee a activer le cytochrome c |
JP2009073765A (ja) * | 2007-09-20 | 2009-04-09 | Nitsukoku Seifun Kk | アンジオテンシン変換酵素(ace)阻害剤組成物及びその製造方法 |
WO2009054504A1 (ja) * | 2007-10-24 | 2009-04-30 | Suntory Holdings Limited | ペルオキシソーム増殖剤応答性受容体(ppar)のリガンド剤 |
FR2925325B1 (fr) * | 2007-12-21 | 2010-02-26 | Vincience | Utilisation d'un hydrolysat de colza en tant que principe actif activateur de la synthese des aquaporines |
US8623445B2 (en) | 2008-05-16 | 2014-01-07 | Bio-Extraction Inc. | Protein concentrates and isolates, and processes for the production thereof |
ES2543782T3 (es) * | 2008-05-16 | 2015-08-21 | Siebte Pmi Verwaltungs Gmbh | Concentrados y aislados de proteínas de semillas oleaginosas y procedimientos para la producción de los mismos |
US8821955B2 (en) | 2008-05-16 | 2014-09-02 | Siebte Pmi Verwaltungs Gmbh | Protein concentrates and isolates, and processes for the production thereof |
JP2010163400A (ja) | 2009-01-19 | 2010-07-29 | Kikkoman Corp | 新規アンジオテンシン変換酵素阻害ペプチド |
WO2010087480A1 (ja) * | 2009-02-02 | 2010-08-05 | 国立大学法人京都大学 | ペプチドを含む医薬または食品 |
JP2010248134A (ja) * | 2009-04-16 | 2010-11-04 | Rheology Kino Shokuhin Kenkyusho:Kk | ペプチド組成物 |
CA2801536C (en) | 2009-11-11 | 2018-10-23 | Bioexx Specialty Proteins Ltd. | Protein concentrates and isolates, and processes for the production thereof from macroalgae and/or microalgae |
DK2498619T3 (en) | 2009-11-11 | 2017-08-07 | Siebte Pmi Verwaltungs Gmbh | PROTEIN CONCENTRATES AND ISOLATES, AND PROCEDURES FOR PRODUCING THEREOF FROM SHAKED OIL PREPARATION |
CN102125096A (zh) * | 2010-12-28 | 2011-07-20 | 江苏欣晖食品有限公司 | 一种降血压豌豆奶粉及其加工方法 |
JP5906560B2 (ja) * | 2011-02-24 | 2016-04-20 | 広島県 | 食品用豆類の製造方法及び食品 |
DE102011005288B4 (de) * | 2011-03-09 | 2018-10-11 | Technische Universität Dresden | Verfahren zur Herstellung eines Proteinhydrolysats mit ACE-hemmenden tryptophanhaltigen Dipeptiden |
WO2012155295A1 (zh) * | 2011-05-17 | 2012-11-22 | 中国食品发酵工业研究院 | 一种工业化生产玉米降压活性肽的方法 |
CA2859827A1 (en) * | 2011-12-19 | 2013-06-27 | Bernard Laarveld | Use of cyclic peptides from flaxseed for improving animal and human health |
JP6296722B2 (ja) * | 2012-07-31 | 2018-03-20 | サンスター株式会社 | 米糠酵素処理組成物 |
US10264805B2 (en) * | 2015-04-23 | 2019-04-23 | Nutriati, Inc. | Dry fractionation for plant based protein extraction |
CN104789629B (zh) * | 2015-04-30 | 2018-10-26 | 中国食品发酵工业研究院 | 一种鹰嘴豆低聚肽及其制备方法 |
CA3004512C (en) | 2015-11-13 | 2023-07-04 | Unilever Plc | Process for the manufacture of an aqueous dispersion comprising mustard bran and oil-in-water emulsion containing such dispersion |
CN107557420B (zh) * | 2017-08-22 | 2020-05-05 | 无锡初晨生物科技有限公司 | 一种亚麻籽粕多肽的制备方法 |
CN109206479B (zh) * | 2017-09-18 | 2021-10-29 | 北京中医药大学 | 一种醋豆谷蛋白源降压肽及其应用 |
CN107460224A (zh) * | 2017-09-28 | 2017-12-12 | 山西琪尔康翅果生物制品有限公司 | 一种翅果低聚肽的制备方法 |
SG11202003642PA (en) * | 2017-11-03 | 2020-05-28 | Cargill Inc | Pea protein hydrolysate |
MX2021008863A (es) | 2019-02-03 | 2021-10-13 | Terviva Inc | Metodos para controlar a la sigatoka negra en los platanos mediante el uso del aceite de millettia y las formulaciones para ello. |
CN111471732A (zh) * | 2020-04-24 | 2020-07-31 | 上海交通大学 | 一种新型富硒茶源ace抑制肽及其制备方法 |
CN112626155B (zh) * | 2020-06-09 | 2022-02-18 | 南京泛成生物科技有限公司 | 一种豌豆肽的制备方法 |
CN111732630B (zh) * | 2020-08-24 | 2021-01-05 | 烟台双塔食品股份有限公司 | 一种降低血压的豌豆寡肽及其制备方法和应用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4175075A (en) * | 1978-07-07 | 1979-11-20 | The Procter & Gamble Company | Isolation of protein from vegetable seeds |
US4739076A (en) | 1985-03-15 | 1988-04-19 | Southwick Philip L | Substituted 3-pyrroline-2-one amino blocking reagents and intermediates therefor |
JP3088491B2 (ja) | 1991-05-29 | 2000-09-18 | 日清製粉株式会社 | ペプチド混合物の製造方法 |
JPH0616568A (ja) * | 1991-09-17 | 1994-01-25 | Chiba Seifun Kk | アンジオテンシン変換酵素阻害剤 |
JPH08269087A (ja) * | 1992-03-02 | 1996-10-15 | Fumio Yamauchi | 新規なテトラペプチド、ペンタペプチドその製法およびそれらを有効成分とする血圧降下剤 |
US5306133A (en) * | 1993-01-21 | 1994-04-26 | Miles J. Willard | Dough sheet rotary cutting system |
US5705618A (en) | 1995-03-31 | 1998-01-06 | Agriculture And Agri-Food Canada | Process for extracting lignans from flaxseed |
KR0156678B1 (ko) | 1996-01-11 | 1998-10-15 | 이상윤 | 안지오텐신 전환효소 저해제 |
US6919314B1 (en) | 1998-06-17 | 2005-07-19 | New Zealand Dairy Board | Bioactive whey protein hydrolysate |
JP4053686B2 (ja) | 1999-04-28 | 2008-02-27 | 仙味エキス株式会社 | 生理活性健康食品 |
-
2003
- 2003-12-24 JP JP2004562417A patent/JP4538326B2/ja not_active Expired - Fee Related
- 2003-12-24 WO PCT/CA2003/002020 patent/WO2004057976A1/en active Application Filing
- 2003-12-24 BR BR0317762-9A patent/BR0317762A/pt not_active Application Discontinuation
- 2003-12-24 CN CN200380107565XA patent/CN1731934B/zh not_active Expired - Fee Related
- 2003-12-24 MX MXPA05006403A patent/MXPA05006403A/es unknown
- 2003-12-24 CA CA2508219A patent/CA2508219C/en not_active Expired - Fee Related
- 2003-12-24 CN CN2007101429739A patent/CN101139625B/zh not_active Expired - Fee Related
- 2003-12-24 US US10/538,951 patent/US7566690B2/en not_active Expired - Fee Related
- 2003-12-24 EP EP03782043A patent/EP1575375A1/en not_active Withdrawn
- 2003-12-24 AU AU2003289794A patent/AU2003289794A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1575375A1 (en) | 2005-09-21 |
CN101139625B (zh) | 2012-11-28 |
MXPA05006403A (es) | 2005-12-05 |
US7566690B2 (en) | 2009-07-28 |
AU2003289794A1 (en) | 2004-07-22 |
WO2004057976A1 (en) | 2004-07-15 |
CN1731934A (zh) | 2006-02-08 |
JP2006512371A (ja) | 2006-04-13 |
JP4538326B2 (ja) | 2010-09-08 |
CA2508219C (en) | 2012-12-18 |
US20060217318A1 (en) | 2006-09-28 |
CN101139625A (zh) | 2008-03-12 |
CN1731934B (zh) | 2010-04-28 |
CA2508219A1 (en) | 2004-07-15 |
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