MX2009012675A - Tensioactivos reconstituidos que tienen propiedades mejoradas. - Google Patents

Tensioactivos reconstituidos que tienen propiedades mejoradas.

Info

Publication number
MX2009012675A
MX2009012675A MX2009012675A MX2009012675A MX2009012675A MX 2009012675 A MX2009012675 A MX 2009012675A MX 2009012675 A MX2009012675 A MX 2009012675A MX 2009012675 A MX2009012675 A MX 2009012675A MX 2009012675 A MX2009012675 A MX 2009012675A
Authority
MX
Mexico
Prior art keywords
improved properties
directed
amino acid
reconstituted surfactants
polypeptide
Prior art date
Application number
MX2009012675A
Other languages
English (en)
Inventor
Jan Johansson
Tore Curstedt
Bengt Robertson
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of MX2009012675A publication Critical patent/MX2009012675A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

La presente invención se relaciona con un tensioactivo reconstituido que comprende un vehículo lípido, un análogo polipeptídico de la proteína de tensioactivo nativo SP-C y un polipéptido que comprende una secuencia de unidades repetidas constituidas de un número de residuos de aminoácidos hidrofóbicos comprendidos entre 3 y 8 y un residuo de aminoácido básico. La invención también se relaciona con sus composiciones farmacéuticas y con su uso para la profilaxis y/o tratamiento de RDS y otros trastornos respiratorios.
MX2009012675A 2007-06-01 2008-05-22 Tensioactivos reconstituidos que tienen propiedades mejoradas. MX2009012675A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07010857A EP1997502A1 (en) 2007-06-01 2007-06-01 Reconstituted surfactants having improved properties
PCT/EP2008/004097 WO2008145298A1 (en) 2007-06-01 2008-05-22 Reconstituted surfactants having improved properties

Publications (1)

Publication Number Publication Date
MX2009012675A true MX2009012675A (es) 2009-12-14

Family

ID=38421186

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012675A MX2009012675A (es) 2007-06-01 2008-05-22 Tensioactivos reconstituidos que tienen propiedades mejoradas.

Country Status (14)

Country Link
US (1) US7897577B2 (es)
EP (2) EP1997502A1 (es)
JP (1) JP5575639B2 (es)
KR (1) KR101516443B1 (es)
CN (1) CN101687006B (es)
AT (1) ATE544461T1 (es)
AU (1) AU2008256449B2 (es)
BR (1) BRPI0811320A2 (es)
CA (1) CA2689066C (es)
EA (1) EA017697B1 (es)
HK (1) HK1140420A1 (es)
MX (1) MX2009012675A (es)
WO (1) WO2008145298A1 (es)
ZA (1) ZA200908445B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021058A1 (it) 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
UA94477C2 (ru) 2006-10-13 2011-05-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Воспроизведенные сурфактанты, которые имеют улучшенные свойства
EP2022798A1 (en) 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides
US8551534B2 (en) 2007-10-10 2013-10-08 Parion Sciences, Inc. Inhaled hypertonic saline delivered by a heated nasal cannula
US8399406B2 (en) * 2009-06-05 2013-03-19 Chiesi Farmaceutici S.P.A. Reconstituted surfactant composition containing analogs of surfactant protein B (SP-B) and surfactant protein C (SP-C)
CA2838529C (en) 2011-06-07 2020-03-24 Parion Sciences, Inc. Methods of treatment
US8945605B2 (en) 2011-06-07 2015-02-03 Parion Sciences, Inc. Aerosol delivery systems, compositions and methods
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
SI2723323T1 (sl) 2012-03-28 2016-04-29 Discovery Laboratories, Inc. Liofilizacija sintetičnega liposomskega pulmonalnega surfaktanta
KR102109223B1 (ko) 2012-05-29 2020-05-11 패리온 사이언스 인코퍼레이티드 안구 건조 및 다른 점막 질환의 치료를 위한 나트륨 채널 차단제 활성을 보유하는 덴드리머 유사 아미노 아미드
RU2018138195A (ru) 2012-12-17 2018-12-18 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4- фенилбутил)карбамимидоил)пиразин-2-карбоксамида
PE20151054A1 (es) 2012-12-17 2015-08-07 Parion Sciences Inc Derivados de cloro-pirazin carboxamida con actividad bloqueadora sobre los canales de sodio epiteliales
CA2896686A1 (en) 2012-12-17 2014-06-26 Parion Sciences, Inc. 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds
KR20170065583A (ko) * 2014-10-01 2017-06-13 플랜트 헬스 케어, 인코포레이티드 과민성 반응 유발제 펩타이드 및 이의 용도
WO2016054342A1 (en) 2014-10-01 2016-04-07 Plant Health Care, Inc. Elicitor peptides having disrupted hypersensitive response box and use thereof
CN108883148A (zh) 2016-04-06 2018-11-23 植物保健公司 过敏反应激发子来源的肽及其用途
BR112018069945A2 (pt) 2016-04-06 2019-02-05 Plant Health Care Inc micróbios benéficos para distribuição de peptídeos ou proteínas efetoras e uso dos mesmos
PL3558376T3 (pl) 2016-12-22 2022-02-14 Chiesi Farmaceutici S.P.A. Kombinacja terapeutyczna zawierająca surfaktant płucny i steroid do leczenia rozwijającej się BPD
MX2020011127A (es) 2018-04-23 2021-01-15 Chiesi Farm Spa Combinacion terapeutica que comprende agente tensioactivo pulmonar y esteroide para la profilaxis de displasia broncopulmonar (bpd).
US20230097886A1 (en) * 2021-07-30 2023-03-30 Ayuvis Research, Inc. Compositions and methods for the treatment of bronchopulmonary dysplasia (bpd) and bpd-associated pulmonary hypertension

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
IT1308180B1 (it) 1999-02-12 2001-12-07 Chiesi Farma Spa Peptidi sintetici aventi la capacita' di diminuire la tensionesuperficiale e loro impiego nella preparazione di un surfattante
CA2372558A1 (en) * 1999-06-11 2000-12-21 Byk Gulden Lomberg Chemische Fabrik Gmbh Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c)
IL164795A0 (en) * 2002-04-25 2005-12-18 Scripps Research Inst Treatment and prevention of pulmonary conditions
ITMI20021058A1 (it) * 2002-05-17 2003-11-17 Chiesi Farma Spa Miscele di lipidi sintetici ottimizzate per la preparazione di un surfattante ricostituito
EP1481665A1 (en) * 2003-05-30 2004-12-01 CHIESI FARMACEUTICI S.p.A. Novel lipid mixtures for synthetic surfactants
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
UA94477C2 (ru) * 2006-10-13 2011-05-10 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Воспроизведенные сурфактанты, которые имеют улучшенные свойства
EP2022798A1 (en) * 2007-08-09 2009-02-11 CHIESI FARMACEUTICI S.p.A. Synthetic pulmonary surfactant peptides

Also Published As

Publication number Publication date
CN101687006A (zh) 2010-03-31
ZA200908445B (en) 2011-02-23
AU2008256449B2 (en) 2012-09-13
EA017697B1 (ru) 2013-02-28
CA2689066A1 (en) 2008-12-04
WO2008145298A1 (en) 2008-12-04
AU2008256449A1 (en) 2008-12-04
HK1140420A1 (en) 2010-10-15
KR101516443B1 (ko) 2015-05-07
EP2152288A1 (en) 2010-02-17
CA2689066C (en) 2016-03-29
CN101687006B (zh) 2013-10-16
US20090088379A1 (en) 2009-04-02
BRPI0811320A2 (pt) 2014-10-21
JP2010528997A (ja) 2010-08-26
EA200901459A1 (ru) 2010-06-30
US7897577B2 (en) 2011-03-01
ATE544461T1 (de) 2012-02-15
EP2152288B1 (en) 2012-02-08
JP5575639B2 (ja) 2014-08-20
EP1997502A1 (en) 2008-12-03
KR20100015802A (ko) 2010-02-12

Similar Documents

Publication Publication Date Title
MX2009012675A (es) Tensioactivos reconstituidos que tienen propiedades mejoradas.
TN2009000099A1 (en) Reconstituted surfactants having improved properties
TN2011000558A1 (en) Improved reconstituted surfactant composition containing analogs of surfactant protein b (sp-b) and surfactant protein c (sp-c)
IN2015DN02553A (es)
IL210668A (en) Glucagon-like peptide-2 (2-glp) analogues and their pharmaceutical preparations
EP3533461A3 (en) Prame derived peptides and immunogenic compositions comprising these
WO2008075369A3 (en) T-140 peptide analogs having cxcr4 super-agonist activity for bone marrow recovery
MX2008009493A (es) Peptido novedoso y uso del mismo.
UA100127C2 (ru) Пептид cdh3 и лекарственное средство, содержащее его
PH12019550241A1 (en) Mic-1 compounds and uses thereof
MX2021003109A (es) Proteina para el tratamiento de enfermedades inflamatorias.
MX2010001543A (es) Peptidos de surfactante pulmonar sintetico.
AU2003251728A8 (en) Placental growth factor as a target for the treatment of osteoporosis
RS20170169A1 (sr) Poboljšana rekonstituisana kompozicija sufraktanta koja sadrži analoge sufraktanta proteina b (sp-b) i surfaktanta proteina c (sp-c)
WO2005087809B1 (en) Peptides from vitronectin and their therapeutic exploitation for osteoblast adhesion
TH127104B (th) สารลดความตึงผิวที่ถูกประกอบขึ้นใหม่โดยมีคุณสมบัติที่ได้รับการปรับปรุงให้ดีขึ้น
UA96003C2 (en) PHARMACEUTICAL COMPOSITION [Aib8,35]hGLP-1(7-36)NH2

Legal Events

Date Code Title Description
HH Correction or change in general
FG Grant or registration