PE20050672A1 - Proceso para la preparacion de aminoalcoholes sustituidos - Google Patents

Proceso para la preparacion de aminoalcoholes sustituidos

Info

Publication number
PE20050672A1
PE20050672A1 PE2004001202A PE2004001202A PE20050672A1 PE 20050672 A1 PE20050672 A1 PE 20050672A1 PE 2004001202 A PE2004001202 A PE 2004001202A PE 2004001202 A PE2004001202 A PE 2004001202A PE 20050672 A1 PE20050672 A1 PE 20050672A1
Authority
PE
Peru
Prior art keywords
aminoalcohols
replaced
preparation
alkyl
manufacturing
Prior art date
Application number
PE2004001202A
Other languages
English (en)
Inventor
Yanzhong Wu
Arkadiy Rubezhov
Jean Schmid
Jay Thomas Afragola
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PE20050672A1 publication Critical patent/PE20050672A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

REFERIDA AL PROCESO DE FABRICACION DE UNA 6-[FENIL(SUSTITUIDO)]-TRIAZOLOPIRIMIDINA DE FORMULA I DONDE R1 Y R2 SON CADA UNO H, ALQUILO C1-C3, ENTRE OTROS; R4 ES H, ALQUILO C1-C3; R5 ES CF3, C2F5; n ES 2-4; X ES Br, I, ENTRE OTROS; DICHA FABRICACION SE REALIZA MEDIANTE REACCION CON UNA AMINA EN AGUA COMO SOLVENTE A UNA TEMPERATURA DE 20-90°C EN PRESENCIA OPCIONAL DE YODUROS METALICOS COMO CATALITICOS OBTENIENDOSE COMPUESTOS INHIBIDORES DE TUBULINA CON UTILIDAD EN CASOS DE CANCER
PE2004001202A 2003-12-08 2004-12-07 Proceso para la preparacion de aminoalcoholes sustituidos PE20050672A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52793003P 2003-12-08 2003-12-08

Publications (1)

Publication Number Publication Date
PE20050672A1 true PE20050672A1 (es) 2005-10-24

Family

ID=34676795

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2004001202A PE20050672A1 (es) 2003-12-08 2004-12-07 Proceso para la preparacion de aminoalcoholes sustituidos

Country Status (21)

Country Link
US (1) US7521552B2 (es)
EP (1) EP1692091A2 (es)
JP (1) JP2007513186A (es)
KR (1) KR20060127402A (es)
CN (1) CN1890244A (es)
AR (1) AR046873A1 (es)
AU (1) AU2004297245A1 (es)
BR (1) BRPI0417442A (es)
CA (1) CA2546907A1 (es)
CO (1) CO5700758A2 (es)
EC (1) ECSP066598A (es)
GT (1) GT200400256A (es)
HN (1) HN2004000518A (es)
IL (1) IL176019A0 (es)
NO (1) NO20062647L (es)
PA (1) PA8619501A1 (es)
PE (1) PE20050672A1 (es)
RU (1) RU2006117985A (es)
TW (1) TW200524843A (es)
WO (1) WO2005056514A2 (es)
ZA (1) ZA200604685B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2522761C2 (ru) * 2008-11-05 2014-07-20 Басф Се Способ получения n, n-замещенных 3-аминопропан-1-олов
CN101784016A (zh) * 2009-01-16 2010-07-21 鸿富锦精密工业（深圳）有限公司 在数码相框上实现发送邮件的方法及系统
CZ301920B6 (cs) * 2009-06-16 2010-07-28 Zentiva, K. S. Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu
CN102753517A (zh) * 2010-02-08 2012-10-24 北达科他州立大学研究基金会 制备多烷基化的低聚亚烷基多胺的方法
KR101675440B1 (ko) * 2014-10-14 2016-11-15 한국화학연구원 광학 활성 3-클로로-1-아릴프로판-1-올 유도체로부터 3-아미노-1-아릴프로판-1-올 유도체의 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1018868B (de) * 1954-11-06 1957-11-07 Rhone Poulenc Sa Verfahren zur Herstellung von Phenthiazinderivaten
GB783289A (en) 1954-11-12 1957-09-18 Rhone Poulenc Sa New phenthiazine derivatives and processes for their preparation
US4874785A (en) * 1985-10-01 1989-10-17 Ethyl Corporation Quaternary ammonium compounds
EP1066291B8 (en) * 1998-03-23 2005-09-14 Basf Aktiengesellschaft Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
US20040039129A1 (en) * 2000-08-16 2004-02-26 Hall Dennis G. Non-pressurized methods for the preparation of conjugrated solid supports for boronic acids

Also Published As

Publication number Publication date
GT200400256A (es) 2005-08-18
PA8619501A1 (es) 2005-08-10
NO20062647L (no) 2006-09-06
AR046873A1 (es) 2005-12-28
BRPI0417442A (pt) 2007-03-13
US7521552B2 (en) 2009-04-21
AU2004297245A1 (en) 2005-06-23
KR20060127402A (ko) 2006-12-12
CO5700758A2 (es) 2006-11-30
IL176019A0 (en) 2006-10-05
CA2546907A1 (en) 2005-06-23
WO2005056514A2 (en) 2005-06-23
US20050124806A1 (en) 2005-06-09
CN1890244A (zh) 2007-01-03
HN2004000518A (es) 2007-03-26
RU2006117985A (ru) 2008-01-20
JP2007513186A (ja) 2007-05-24
TW200524843A (en) 2005-08-01
ZA200604685B (en) 2009-03-25
ECSP066598A (es) 2006-10-25
EP1692091A2 (en) 2006-08-23
WO2005056514A3 (en) 2005-08-11

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