ECSP066598A - Proceso para la preparación de amino alcoholes sustituidos - Google Patents

Proceso para la preparación de amino alcoholes sustituidos

Info

Publication number
ECSP066598A
ECSP066598A EC2006006598A ECSP066598A ECSP066598A EC SP066598 A ECSP066598 A EC SP066598A EC 2006006598 A EC2006006598 A EC 2006006598A EC SP066598 A ECSP066598 A EC SP066598A EC SP066598 A ECSP066598 A EC SP066598A
Authority
EC
Ecuador
Prior art keywords
preparation
amino substituted
substituted alcohols
haloalcohols
useful
Prior art date
Application number
EC2006006598A
Other languages
English (en)
Inventor
Arkadiy Rubezhov
Jean Schmid
Jay Thomas Afragola
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of ECSP066598A publication Critical patent/ECSP066598A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se suministra un proceso para la preparación de amino alcoholes sustituidos HO-(CH2)n-NR1R2 de haloalcoholes HO-(CH2)n-X, donde X es Cl, Br, o I, mediante la reacción con una amina HNR1R2, en agua como solvente a temperatura en el rango de aproximadamente 20°C a aproximadamente 90°C opcionalmente en la presencia de una cantidad catalítica de unos yoduros metálicos fuente de yoduro. Los haloalcoholes son útiles en la preparación de compuestos 6-[fenilo(sustituido)]-triazolopirimidina que son útiles en el tratamiento de cáncer.
EC2006006598A 2003-12-08 2006-06-02 Proceso para la preparación de amino alcoholes sustituidos ECSP066598A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52793003P 2003-12-08 2003-12-08

Publications (1)

Publication Number Publication Date
ECSP066598A true ECSP066598A (es) 2006-10-25

Family

ID=34676795

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2006006598A ECSP066598A (es) 2003-12-08 2006-06-02 Proceso para la preparación de amino alcoholes sustituidos

Country Status (21)

Country Link
US (1) US7521552B2 (es)
EP (1) EP1692091A2 (es)
JP (1) JP2007513186A (es)
KR (1) KR20060127402A (es)
CN (1) CN1890244A (es)
AR (1) AR046873A1 (es)
AU (1) AU2004297245A1 (es)
BR (1) BRPI0417442A (es)
CA (1) CA2546907A1 (es)
CO (1) CO5700758A2 (es)
EC (1) ECSP066598A (es)
GT (1) GT200400256A (es)
HN (1) HN2004000518A (es)
IL (1) IL176019A0 (es)
NO (1) NO20062647L (es)
PA (1) PA8619501A1 (es)
PE (1) PE20050672A1 (es)
RU (1) RU2006117985A (es)
TW (1) TW200524843A (es)
WO (1) WO2005056514A2 (es)
ZA (1) ZA200604685B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102203054B (zh) * 2008-11-05 2014-07-30 巴斯夫欧洲公司 生产n，n-取代的3-氨基丙-1-醇的方法
CN101784016A (zh) * 2009-01-16 2010-07-21 鸿富锦精密工业（深圳）有限公司 在数码相框上实现发送邮件的方法及系统
CZ2009385A3 (cs) * 2009-06-16 2010-07-28 Zentiva, K. S. Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu
WO2011097490A1 (en) * 2010-02-08 2011-08-11 Ndsu Research Foundation Method of producing polyalkylated oligoalkylenepolyamines
KR101675440B1 (ko) * 2014-10-14 2016-11-15 한국화학연구원 광학 활성 3-클로로-1-아릴프로판-1-올 유도체로부터 3-아미노-1-아릴프로판-1-올 유도체의 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1018868B (de) * 1954-11-06 1957-11-07 Rhone Poulenc Sa Verfahren zur Herstellung von Phenthiazinderivaten
GB783289A (en) 1954-11-12 1957-09-18 Rhone Poulenc Sa New phenthiazine derivatives and processes for their preparation
US4874785A (en) * 1985-10-01 1989-10-17 Ethyl Corporation Quaternary ammonium compounds
CA2324154C (en) * 1998-03-23 2008-03-18 American Cyanamid Company Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
CA2419238A1 (en) * 2000-08-16 2002-02-21 University Of Alberta Non-pressurized methods for the preparation of conjugated solid supports for boronic acids

Also Published As

Publication number Publication date
KR20060127402A (ko) 2006-12-12
NO20062647L (no) 2006-09-06
GT200400256A (es) 2005-08-18
PE20050672A1 (es) 2005-10-24
RU2006117985A (ru) 2008-01-20
CO5700758A2 (es) 2006-11-30
IL176019A0 (en) 2006-10-05
JP2007513186A (ja) 2007-05-24
CA2546907A1 (en) 2005-06-23
EP1692091A2 (en) 2006-08-23
AU2004297245A1 (en) 2005-06-23
US7521552B2 (en) 2009-04-21
HN2004000518A (es) 2007-03-26
AR046873A1 (es) 2005-12-28
CN1890244A (zh) 2007-01-03
WO2005056514A3 (en) 2005-08-11
BRPI0417442A (pt) 2007-03-13
US20050124806A1 (en) 2005-06-09
WO2005056514A2 (en) 2005-06-23
PA8619501A1 (es) 2005-08-10
ZA200604685B (en) 2009-03-25
TW200524843A (en) 2005-08-01

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