AR046873A1 - Proceso para la preparacion de aminoalcoholes sustituidos - Google Patents

Proceso para la preparacion de aminoalcoholes sustituidos

Info

Publication number
AR046873A1
AR046873A1 ARP040104568A ARP040104568A AR046873A1 AR 046873 A1 AR046873 A1 AR 046873A1 AR P040104568 A ARP040104568 A AR P040104568A AR P040104568 A ARP040104568 A AR P040104568A AR 046873 A1 AR046873 A1 AR 046873A1
Authority
AR
Argentina
Prior art keywords
preparation
substituted
atoms
aminoalcoholes
alkyl
Prior art date
Application number
ARP040104568A
Other languages
English (en)
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of AR046873A1 publication Critical patent/AR046873A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Los haloalcoholes son útiles en la preparación de compuestos de 6-[fenil](sustituido)]-triazolopirimidina los cuales son útiles en el tratamiento del cáncer. Reivindicación 1: Un proceso para la preparación de un aminoalcohol sustituido de la fórmula HO-(CH2)n-NR1R2 en donde R1 y R2 son cada uno independientemente H o alquilo C1-3, o R1 y R2 cuando opcionalmente son tomados en forma conjunta con el átomo de N al cual cada uno está unido forman un anillo heterocíclico saturado de 4 a 6 miembros que tiene 1-2 átomos de N y 0-1 átomos de O o 0-1 átomos de S, y opcionalmente con R3; n es un número entero de 2 a 7; R3 es alquilo C1-3; el cual comprende la reacción de un haloalcohol de la fórmula HO-(CH2)n-X en donde X es Cl, Br, o I, con una amina NHR1R2, en agua como solvente a un rango de temperatura entre aproximadamente 20sC y aproximadamente 90sC.
ARP040104568A 2003-12-08 2004-12-07 Proceso para la preparacion de aminoalcoholes sustituidos AR046873A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52793003P 2003-12-08 2003-12-08

Publications (1)

Publication Number Publication Date
AR046873A1 true AR046873A1 (es) 2005-12-28

Family

ID=34676795

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP040104568A AR046873A1 (es) 2003-12-08 2004-12-07 Proceso para la preparacion de aminoalcoholes sustituidos

Country Status (21)

Country Link
US (1) US7521552B2 (es)
EP (1) EP1692091A2 (es)
JP (1) JP2007513186A (es)
KR (1) KR20060127402A (es)
CN (1) CN1890244A (es)
AR (1) AR046873A1 (es)
AU (1) AU2004297245A1 (es)
BR (1) BRPI0417442A (es)
CA (1) CA2546907A1 (es)
CO (1) CO5700758A2 (es)
EC (1) ECSP066598A (es)
GT (1) GT200400256A (es)
HN (1) HN2004000518A (es)
IL (1) IL176019A0 (es)
NO (1) NO20062647L (es)
PA (1) PA8619501A1 (es)
PE (1) PE20050672A1 (es)
RU (1) RU2006117985A (es)
TW (1) TW200524843A (es)
WO (1) WO2005056514A2 (es)
ZA (1) ZA200604685B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2590457T3 (es) * 2008-11-05 2016-11-22 Basf Se Procedimiento para la producción de 3-aminopropano-1-oles N,N-sustituidos
CN101784016A (zh) * 2009-01-16 2010-07-21 鸿富锦精密工业(深圳)有限公司 在数码相框上实现发送邮件的方法及系统
CZ2009385A3 (cs) * 2009-06-16 2010-07-28 Zentiva, K. S. Zpusob výroby (S)-4-methylamino-3-(3,4-dichlorfenyl)butan-1-olu
WO2011097490A1 (en) * 2010-02-08 2011-08-11 Ndsu Research Foundation Method of producing polyalkylated oligoalkylenepolyamines
KR101675440B1 (ko) * 2014-10-14 2016-11-15 한국화학연구원 광학 활성 3-클로로-1-아릴프로판-1-올 유도체로부터 3-아미노-1-아릴프로판-1-올 유도체의 제조방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1018868B (de) * 1954-11-06 1957-11-07 Rhone Poulenc Sa Verfahren zur Herstellung von Phenthiazinderivaten
GB783289A (en) 1954-11-12 1957-09-18 Rhone Poulenc Sa New phenthiazine derivatives and processes for their preparation
US4874785A (en) * 1985-10-01 1989-10-17 Ethyl Corporation Quaternary ammonium compounds
CN100339378C (zh) * 1998-03-23 2007-09-26 巴斯福股份公司 杀真菌的6-(2-卤代-4-烷氧基苯基)-三唑并嘧啶
AU2001287399A1 (en) * 2000-08-16 2002-02-25 University Of Alberta Non-pressurized methods for the preparation of conjugated solid supports for boronic acids

Also Published As

Publication number Publication date
RU2006117985A (ru) 2008-01-20
CA2546907A1 (en) 2005-06-23
PA8619501A1 (es) 2005-08-10
CO5700758A2 (es) 2006-11-30
ECSP066598A (es) 2006-10-25
PE20050672A1 (es) 2005-10-24
CN1890244A (zh) 2007-01-03
BRPI0417442A (pt) 2007-03-13
HN2004000518A (es) 2007-03-26
US20050124806A1 (en) 2005-06-09
TW200524843A (en) 2005-08-01
JP2007513186A (ja) 2007-05-24
ZA200604685B (en) 2009-03-25
IL176019A0 (en) 2006-10-05
KR20060127402A (ko) 2006-12-12
US7521552B2 (en) 2009-04-21
NO20062647L (no) 2006-09-06
WO2005056514A3 (en) 2005-08-11
AU2004297245A1 (en) 2005-06-23
WO2005056514A2 (en) 2005-06-23
EP1692091A2 (en) 2006-08-23
GT200400256A (es) 2005-08-18

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