PE20020994A1 - Composicion antifungal con aumentada biodisponibilidad - Google Patents

Composicion antifungal con aumentada biodisponibilidad

Info

Publication number
PE20020994A1
PE20020994A1 PE2002000263A PE2002000263A PE20020994A1 PE 20020994 A1 PE20020994 A1 PE 20020994A1 PE 2002000263 A PE2002000263 A PE 2002000263A PE 2002000263 A PE2002000263 A PE 2002000263A PE 20020994 A1 PE20020994 A1 PE 20020994A1
Authority
PE
Peru
Prior art keywords
acid
liquid
biodavailability
triazol
refers
Prior art date
Application number
PE2002000263A
Other languages
English (en)
Spanish (es)
Inventor
David Harris
Stefan Sharpe
Joel Sequeira
Shashank Mahashabde
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23076102&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20020994(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20020994A1 publication Critical patent/PE20020994A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PE2002000263A 2001-04-03 2002-04-02 Composicion antifungal con aumentada biodisponibilidad PE20020994A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28113901P 2001-04-03 2001-04-03

Publications (1)

Publication Number Publication Date
PE20020994A1 true PE20020994A1 (es) 2002-11-01

Family

ID=23076102

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000263A PE20020994A1 (es) 2001-04-03 2002-04-02 Composicion antifungal con aumentada biodisponibilidad

Country Status (18)

Country Link
US (2) US20030055067A1 (enExample)
EP (2) EP1372394A1 (enExample)
JP (2) JP4308902B2 (enExample)
KR (1) KR100607742B1 (enExample)
CN (1) CN100415234C (enExample)
AR (1) AR033096A1 (enExample)
AU (1) AU2002257104B2 (enExample)
BR (1) BR0208626A (enExample)
CA (1) CA2443089C (enExample)
HU (1) HUP0400856A3 (enExample)
MX (1) MXPA03009021A (enExample)
NO (1) NO20034419L (enExample)
NZ (1) NZ528363A (enExample)
PE (1) PE20020994A1 (enExample)
PL (1) PL212985B1 (enExample)
TW (1) TWI311464B (enExample)
WO (1) WO2002080678A1 (enExample)
ZA (1) ZA200307684B (enExample)

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* Cited by examiner, † Cited by third party
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US20030072807A1 (en) * 2000-12-22 2003-04-17 Wong Joseph Chung-Tak Solid particulate antifungal compositions for pharmaceutical use
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
IL160570A0 (en) 2001-09-26 2004-07-25 Baxter Int Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US20060009469A1 (en) * 2004-05-28 2006-01-12 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmacutical compositions of posaconazole
US20060160823A1 (en) * 2004-05-28 2006-07-20 Leonore Witchey-Lakshmanan Particulate-stabilized injectable pharmaceutical compositions of Posaconazole
CA2567803A1 (en) * 2004-05-28 2005-12-15 Schering Corporation Injectable pharmaceutical suspension comprising posaconazole
US7473684B2 (en) * 2005-09-16 2009-01-06 Selamine Limited Bisphosphonate formulation
BRPI0712130A2 (pt) 2006-05-30 2012-01-17 Elan Pharma Int Ltd formulações de posaconazol em nanopartìculas
WO2007144362A1 (en) 2006-06-14 2007-12-21 Intervet International B.V. A suspension comprising benzimidazole carbamate and a polysorbate
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
FR2910323A1 (fr) * 2006-12-26 2008-06-27 Virbac Sa Sa Composition liquide anhydre destinee a etre incorporee a l'eau de boisson des animaux d'elevage.
DE102008004893A1 (de) * 2008-01-17 2009-07-23 Add Technologies Ltd. Trägerpellets, Verfahren zu deren Herstellung und deren Verwendung
PE20091778A1 (es) * 2008-04-15 2009-11-13 Schering Corp Composiciones de alta densidad que contienen posaconazol y formulaciones que lo comprenden
EP2278957A2 (en) * 2008-04-15 2011-02-02 Schering Corporation Oral pharmaceutical compositions in a solid dispersion comprising preferably posaconazole and hpmcas
EP2130540A1 (en) 2008-06-02 2009-12-09 Sandoz AG Pharmaceutical compositions containing a crystalline form of posaconazole
EP2141159A1 (en) 2008-07-03 2010-01-06 Sandoz AG A Crystalline form of posaconazole
EP2451805A1 (en) 2009-07-09 2012-05-16 Sandoz AG A crystalline form of posaconazole
AU2011254657B2 (en) 2010-05-19 2016-02-04 Sandoz Ag Preparation of posaconazole intermediates
CA2798010C (en) 2010-05-19 2018-09-25 Sandoz Ag Purification of posaconazole and of posaconazole intermediates
RU2588570C2 (ru) 2010-05-19 2016-07-10 Сандоз Аг Способ получения хиральных гидразидов
RU2585760C2 (ru) 2010-05-19 2016-06-10 Сандоз Аг Способ получения хиральных триазолонов
CA2838051C (en) 2011-06-16 2019-09-24 Sandoz Ag Process for the preparation of a chiral compound
CN104379132A (zh) 2012-06-14 2015-02-25 桑多斯股份公司 包含结晶泊沙康唑的药物组合物
CA2963625C (en) 2014-12-05 2023-08-22 Pulmocide Limited 4-(4-(4-(((3r,5r)-5-((1h-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl)piperazin-1-yl)-n-(4-fluorophenyl)benzamide or salts thereof, and use to treat mycoses
ES2790723T3 (es) * 2015-05-21 2020-10-29 Pulmocide Ltd Antifúngico 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-il)metil)-5-(2,4-difluorofenil)tetrahidrofurano-3-il)metoxi)-3-metilfenil)piperazina-1-il)-N -(2-hidroxiciclohexil)benzamida, o una sal farmacéuticamente aceptable del mismo
CN105030668B (zh) * 2015-06-26 2018-03-27 济川药业集团有限公司 泊沙康唑口服混悬剂及其制备方法
CN106333925B (zh) * 2015-07-10 2019-06-18 上海美悦生物科技发展有限公司 一种泊沙康唑液体混悬剂及其制备方法
MX376201B (es) * 2015-12-30 2025-03-07 Nqp 1598 Ltd Compuestos inhibidores de metaloenzima.
CN106389390A (zh) * 2016-06-30 2017-02-15 重庆华邦制药有限公司 泊沙康唑涂膜剂及其制备方法
CN107625729A (zh) * 2017-09-29 2018-01-26 重庆华邦制药有限公司 泊沙康唑口服混悬液及其制备方法
CN110507609B (zh) * 2018-05-21 2021-09-17 上海医药工业研究院 泊沙康唑口服混悬剂的制备方法
GB201917867D0 (en) 2019-12-06 2020-01-22 Pulmocide Ltd Polymorphs
KR20230009946A (ko) * 2020-05-12 2023-01-17 셀릭스 바이오 프라이빗 리미티드 트라이아졸 화합물의 염의 제조 방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4533254A (en) 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5399363A (en) 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5552160A (en) 1991-01-25 1996-09-03 Nanosystems L.L.C. Surface modified NSAID nanoparticles
AU642066B2 (en) 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
US5661151A (en) * 1993-12-21 1997-08-26 Schering Corporation Tetrahydrofuran antifungals
AU681753B2 (en) * 1993-12-21 1997-09-04 Merck Sharp & Dohme Corp. Tetrahydrofuran antifungals
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5580579A (en) * 1995-02-15 1996-12-03 Nano Systems L.L.C. Site-specific adhesion within the GI tract using nanoparticles stabilized by high molecular weight, linear poly (ethylene oxide) polymers
AU7587496A (en) * 1995-11-20 1997-06-11 Banyu Pharmaceutical Co., Ltd. Antifungal composition
US5834472A (en) * 1996-05-24 1998-11-10 Schering Corporation Antifungal composition with enhanced bioavailability
US5846971A (en) 1996-06-28 1998-12-08 Schering Corporation Oral antifungal composition
WO1998051281A1 (en) * 1997-05-14 1998-11-19 Senju Pharmaceutical Co., Ltd. Aqueous suspension preparations with excellent redispersibility
DE69914742T2 (de) 1998-05-29 2004-11-25 Skyepharma Canada Inc., Verdun Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug

Also Published As

Publication number Publication date
AU2002257104B2 (en) 2006-02-09
BR0208626A (pt) 2004-03-09
US8263600B2 (en) 2012-09-11
NO20034419D0 (no) 2003-10-02
MXPA03009021A (es) 2004-02-12
KR20030087052A (ko) 2003-11-12
ZA200307684B (en) 2005-03-30
JP2004527525A (ja) 2004-09-09
PL212985B1 (pl) 2012-12-31
EP2090165A3 (en) 2012-03-28
EP1372394A1 (en) 2004-01-02
JP4308902B2 (ja) 2009-08-05
KR100607742B1 (ko) 2006-08-01
CA2443089C (en) 2011-11-01
EP2090165A2 (en) 2009-08-19
NO20034419L (no) 2003-12-02
CN100415234C (zh) 2008-09-03
CA2443089A1 (en) 2002-10-17
HUP0400856A3 (en) 2012-09-28
AR033096A1 (es) 2003-12-03
US20030055067A1 (en) 2003-03-20
NZ528363A (en) 2005-04-29
WO2002080678A1 (en) 2002-10-17
HUP0400856A2 (hu) 2004-08-30
JP2008120836A (ja) 2008-05-29
PL363965A1 (en) 2004-11-29
TWI311464B (en) 2009-07-01
CN1499930A (zh) 2004-05-26
US20110244004A1 (en) 2011-10-06

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