PE20000537A1 - Composicion farmaceutica dispersable que contiene antagonistas de sustancia p de piperidina - Google Patents
Composicion farmaceutica dispersable que contiene antagonistas de sustancia p de piperidinaInfo
- Publication number
- PE20000537A1 PE20000537A1 PE1999000436A PE00043699A PE20000537A1 PE 20000537 A1 PE20000537 A1 PE 20000537A1 PE 1999000436 A PE1999000436 A PE 1999000436A PE 00043699 A PE00043699 A PE 00043699A PE 20000537 A1 PE20000537 A1 PE 20000537A1
- Authority
- PE
- Peru
- Prior art keywords
- weight
- substance
- antagonist
- fatty acid
- oil
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title abstract 4
- 239000003890 substance P antagonist Substances 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 abstract 3
- -1 POLYOXYETHYLENE Polymers 0.000 abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 239000000194 fatty acid Substances 0.000 abstract 2
- 229930195729 fatty acid Natural products 0.000 abstract 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 abstract 1
- WZKSXHQDXQKIQJ-UHFFFAOYSA-N F[C](F)F Chemical group F[C](F)F WZKSXHQDXQKIQJ-UHFFFAOYSA-N 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- DOOTYTYQINUNNV-UHFFFAOYSA-N Triethyl citrate Chemical compound CCOC(=O)CC(O)(C(=O)OCC)CC(=O)OCC DOOTYTYQINUNNV-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 235000005687 corn oil Nutrition 0.000 abstract 1
- 239000002285 corn oil Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000002105 nanoparticle Substances 0.000 abstract 1
- 239000003921 oil Substances 0.000 abstract 1
- 235000019198 oils Nutrition 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000002269 spontaneous effect Effects 0.000 abstract 1
- 239000001069 triethyl citrate Substances 0.000 abstract 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 abstract 1
- 235000013769 triethyl citrate Nutrition 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Immunology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9811200.6A GB9811200D0 (en) | 1998-05-26 | 1998-05-26 | Organic compounds |
| GBGB9818105.0A GB9818105D0 (en) | 1998-08-19 | 1998-08-19 | Organic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000537A1 true PE20000537A1 (es) | 2000-07-10 |
Family
ID=26313736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000436A PE20000537A1 (es) | 1998-05-26 | 1999-05-25 | Composicion farmaceutica dispersable que contiene antagonistas de sustancia p de piperidina |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US20020156099A1 (enExample) |
| EP (1) | EP1082119B1 (enExample) |
| JP (1) | JP4083985B2 (enExample) |
| KR (1) | KR20010043669A (enExample) |
| CN (1) | CN1270714C (enExample) |
| AR (1) | AR018376A1 (enExample) |
| AT (1) | ATE257380T1 (enExample) |
| AU (1) | AU755134B2 (enExample) |
| BE (1) | BE1012143A5 (enExample) |
| BR (1) | BR9910696A (enExample) |
| CA (1) | CA2333154C (enExample) |
| DE (2) | DE19983247T1 (enExample) |
| DK (1) | DK1082119T3 (enExample) |
| ES (1) | ES2214859T3 (enExample) |
| FR (1) | FR2779145B1 (enExample) |
| GB (1) | GB2353473A (enExample) |
| HU (1) | HUP0102202A3 (enExample) |
| ID (1) | ID27096A (enExample) |
| IL (1) | IL139501A0 (enExample) |
| IT (1) | IT1313551B1 (enExample) |
| NO (1) | NO20005920L (enExample) |
| NZ (1) | NZ508325A (enExample) |
| PE (1) | PE20000537A1 (enExample) |
| PL (1) | PL344245A1 (enExample) |
| PT (1) | PT1082119E (enExample) |
| RU (1) | RU2240121C2 (enExample) |
| SK (1) | SK17752000A3 (enExample) |
| TR (1) | TR200003502T2 (enExample) |
| TW (1) | TW537894B (enExample) |
| WO (1) | WO1999061025A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW537894B (en) | 1998-05-26 | 2003-06-21 | Novartis Ag | A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist |
| AU2003225260A1 (en) * | 2002-04-22 | 2003-11-03 | University Of Florida | Microemulsions for selective molecular separation |
| GB0220953D0 (en) | 2002-09-10 | 2002-10-23 | Novartis Ag | Organic compounds |
| US7842791B2 (en) | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
| FR2935001B1 (fr) * | 2008-08-14 | 2011-12-30 | Commissariat Energie Atomique | Emulsion fluorescente |
| FR2934953B1 (fr) | 2008-08-14 | 2011-01-21 | Commissariat Energie Atomique | Nanoemulsions de nanocristaux |
| FR2934955B1 (fr) | 2008-08-14 | 2011-07-08 | Commissariat Energie Atomique | Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions |
| FR2934954B1 (fr) | 2008-08-14 | 2011-07-22 | Commissariat Energie Atomique | Emulsion fluorescente de vert d'indocyanine |
| EP2938324B1 (en) | 2012-12-31 | 2023-11-08 | JRX Biotechnology, Inc. | Liquid topical pharmaceutical nano-emulsion formulations |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3305689A1 (de) | 1983-02-18 | 1984-08-23 | Mack Chem Pharm | Pharmazeutische zubereitung mit retardwirkung |
| US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
| MY110227A (en) * | 1991-08-12 | 1998-03-31 | Ciba Geigy Ag | 1-acylpiperindine compounds. |
| DE4220616C2 (de) | 1992-06-24 | 1994-12-22 | Byk Gulden Lomberg Chem Fab | Dexniguldipin zur intravenösen Verabreichung |
| ES2168271T3 (es) | 1992-09-25 | 2002-06-16 | Novartis Ag | Composiciones farmaceuticas que contienen ciclosporinas. |
| GB2278780B (en) * | 1993-05-27 | 1998-10-14 | Sandoz Ltd | Macrolide formulations |
| US5952004A (en) * | 1994-03-18 | 1999-09-14 | Shire Laboratories Inc. | Emulsified drug delivery systems |
| TW397825B (en) * | 1994-10-14 | 2000-07-11 | Novartis Ag | Aroyl-piperidine derivatives |
| GB2308545B (en) | 1994-10-26 | 1999-06-02 | Novartis Ag | Pharmaceutical microemulsion preconcentrates |
| IL115742A (en) * | 1994-10-26 | 2000-06-01 | Novartis Ag | Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant |
| FR2728165A1 (fr) * | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un antagoniste de substance p pour le traitement des rougeurs cutanees d'origine neurogene |
| FR2728169A1 (fr) * | 1994-12-19 | 1996-06-21 | Oreal | Utilisation d'un antagoniste de substance p pour le traitement des prurits et des dysesthesies oculaires ou palpebrales |
| WO1996030367A1 (en) * | 1995-03-27 | 1996-10-03 | Hisamitsu Pharmaceutical Co., Inc. | Piperidine derivatives |
| NZ280689A (en) | 1995-12-15 | 1997-08-22 | Bernard Charles Sherma Sherman | Pharmaceutical composition comprising a cyclosporipharmaceutical composition comprising a cyclosporin; a tocol, tocopherol or tocotrienol; and propylen; a tocol, tocopherol or tocotrienol; and propylene carbonate or polyethylene glycol ne carbonate or polyethylene glycol |
| GB9601120D0 (en) | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
| WO1997045119A1 (en) | 1996-05-24 | 1997-12-04 | Novartis Ag | Use of substance p antagonists for treating social phobia |
| TW537894B (en) | 1998-05-26 | 2003-06-21 | Novartis Ag | A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist |
-
1999
- 1999-05-24 TW TW088108449A patent/TW537894B/zh not_active IP Right Cessation
- 1999-05-24 AR ARP990102454A patent/AR018376A1/es not_active Application Discontinuation
- 1999-05-25 PE PE1999000436A patent/PE20000537A1/es not_active Application Discontinuation
- 1999-05-25 BE BE9900364A patent/BE1012143A5/fr not_active IP Right Cessation
- 1999-05-26 KR KR1020007012871A patent/KR20010043669A/ko not_active Ceased
- 1999-05-26 ES ES99927760T patent/ES2214859T3/es not_active Expired - Lifetime
- 1999-05-26 TR TR2000/03502T patent/TR200003502T2/xx unknown
- 1999-05-26 HU HU0102202A patent/HUP0102202A3/hu unknown
- 1999-05-26 SK SK1775-2000A patent/SK17752000A3/sk unknown
- 1999-05-26 AU AU45008/99A patent/AU755134B2/en not_active Ceased
- 1999-05-26 AT AT99927760T patent/ATE257380T1/de not_active IP Right Cessation
- 1999-05-26 RU RU2000133308/15A patent/RU2240121C2/ru not_active IP Right Cessation
- 1999-05-26 IT IT1999MI001164A patent/IT1313551B1/it active
- 1999-05-26 PL PL99344245A patent/PL344245A1/xx unknown
- 1999-05-26 PT PT99927760T patent/PT1082119E/pt unknown
- 1999-05-26 JP JP2000550485A patent/JP4083985B2/ja not_active Expired - Fee Related
- 1999-05-26 CN CNB998066036A patent/CN1270714C/zh not_active Expired - Fee Related
- 1999-05-26 NZ NZ508325A patent/NZ508325A/xx unknown
- 1999-05-26 FR FR9906629A patent/FR2779145B1/fr not_active Expired - Fee Related
- 1999-05-26 EP EP99927760A patent/EP1082119B1/en not_active Expired - Lifetime
- 1999-05-26 GB GB0028506A patent/GB2353473A/en not_active Withdrawn
- 1999-05-26 DK DK99927760T patent/DK1082119T3/da active
- 1999-05-26 ID IDW20002316A patent/ID27096A/id unknown
- 1999-05-26 DE DE19983247T patent/DE19983247T1/de not_active Withdrawn
- 1999-05-26 DE DE69914077T patent/DE69914077T2/de not_active Expired - Lifetime
- 1999-05-26 WO PCT/EP1999/003623 patent/WO1999061025A1/en not_active Ceased
- 1999-05-26 CA CA002333154A patent/CA2333154C/en not_active Expired - Fee Related
- 1999-05-26 BR BR9910696-5A patent/BR9910696A/pt not_active Application Discontinuation
- 1999-05-26 IL IL13950199A patent/IL139501A0/xx unknown
-
2000
- 2000-11-23 NO NO20005920A patent/NO20005920L/no not_active Application Discontinuation
-
2002
- 2002-04-10 US US10/119,549 patent/US20020156099A1/en not_active Abandoned
-
2003
- 2003-03-04 US US10/379,345 patent/US6949257B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR102407735B1 (ko) | 나노에멀젼 전달 시스템의 조성물 | |
| DE4308282C2 (de) | Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices | |
| CN106691888B (zh) | 一种高皮肤滞留光甘草定纳米组合物及其制备方法和用途 | |
| US20060110418A1 (en) | Water-in-oil emulsions and methods | |
| EP0347306B1 (fr) | Composition parfumante, à phase aqueuse continue, ayant une forte concentration en parfum | |
| TW201714605A (zh) | 具有可逆的連續及分散相之奈米乳液 | |
| PE20000537A1 (es) | Composicion farmaceutica dispersable que contiene antagonistas de sustancia p de piperidina | |
| CA2518200A1 (fr) | Poudre impregnee ameliorant la biodisponibilite et/ou la solubilite et procede de fabrication | |
| RU2013145709A (ru) | Офтальмическая композиция | |
| AU2014359195A1 (en) | Lipid microcapsules preferably comprising a lipophilic active substance and composition containing same, method for the production thereof, and use of same in dermatology and in cosmetics | |
| CN102906317A (zh) | 纳米纤维 | |
| RU2010104979A (ru) | Композиция эмульсии "масло в воде" и способ ее получения | |
| CN1582140A (zh) | 具有改善的皮肤和材料柔软的护肤品 | |
| NZ600999A (en) | Cutaneous composition comprising vitamin d analogue and a mixture of solvent and surfactants | |
| RU2015131700A (ru) | Фармацевтические композиции, включающие производное камптотецина | |
| JP2010531684A5 (enExample) | ||
| JP2008273881A (ja) | 多層被覆油粒子、その水分散液、及びそれらの製造方法 | |
| JP2012523408A (ja) | ジクロフェナクの安定な医薬組成物 | |
| Jaromin et al. | Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum | |
| Kichou et al. | Efficiency of emulsifier‐free emulsions in delivering caffeine and α‐tocopherol to human skin | |
| Khalil et al. | Influence of formulation parameters on the physicochemical properties of meloxicam-loaded solid lipid nanoparticles | |
| RU2007137182A (ru) | Микроэмульсии соединений, связывающихся с каннабиноидными рецепторами | |
| KR100350179B1 (ko) | Sedds로 제제화한 발기부전치료용 주입액제 | |
| US20190388543A1 (en) | Formulations and methods for compositions used in wearable drug delivery devices | |
| KR20190026816A (ko) | 약제학적 조성물 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |